Nebivolol Flashcards

Study Notes

Brand Information

Brand name: Bystolic
Generic name: Nebivolol

Indications

Approved for treating hypertension

Dosing Guidelines

Starting dose: 5 mg once daily
Potential dose increase at 2-week intervals, max 40 mg once daily
Applicable for monotherapy or in combination therapy
Patients with severe renal or moderate hepatic impairment: starting dose 2.5 mg once daily

Available Strengths and Dosage Forms

Tablet strengths: 2.5 mg, 5 mg, 10 mg, 20 mg

Medication Class

Classified as an antihypertensive agent

Pharmacology

Primarily acts as a β1-adrenergic blocker; acts as both β1 and β2 blocker in poor metabolizers and higher doses
Results in decreased heart rate, reduced myocardial contractibility, vasodilation, and decreased peripheral resistance
Suppresses renin activity and diminishes tonic sympathetic outflow

Drug Interactions

CYP2D6 inhibitors (e.g., paroxetine, fluoxetine): may elevate plasma levels
CYP2D6 inducers: may lower plasma levels
Use with digitalis glycosides and non-dihydropyridine calcium channel blockers (e.g., verapamil, diltiazem): risk of excessive bradycardia
No interactions classified as risk X/D

Side Effects

Common effects include headache, nausea, fatigue, and dizziness
None of the side effects exceed a 10% occurrence rate

Contraindications

Not for use in severe bradycardia, first-degree heart block, cardiogenic shock, decompensated cardiac failure, and sick sinus syndrome (without a pacemaker)
Avoid in severe hepatic impairment and hypersensitivity to any component
Sudden discontinuation may worsen angina, myocardial infarction, or ventricular arrhythmias
Caution advised for bronchospastic patients
Can mask hypoglycemic symptoms in diabetic patients
Classified as Pregnancy Category C

Patient Counseling

Store in a cool, dry place away from light and children
If a dose is missed, take as soon as possible; skip if it's near next dose time—do not double doses
Consult a physician for severe or persistent side effects
Do not stop taking without consulting a physician
May cause drowsiness; exercise caution in activities requiring alertness
Diabetic patients should be aware of symptom masking
Avoid nonprescription cold, cough, and allergy medications unless directed

Description

Test your knowledge on Nebivolol with these flashcards. The cards cover various aspects such as brand name, indications for use, and dosing guidelines. Enhance your understanding of this medication and its applications in treating hypertension.

Nebivolol Flashcards

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Questions and Answers

What is the brand name for Nebivolol?

What is the generic name for Bystolic?

What is Nebivolol indicated for?

The recommended starting dose of Nebivolol is ______ once daily.

What are the available strengths of Nebivolol tablets?

What class of medication does Nebivolol belong to?

How does Nebivolol primarily act in the body?

Which of the following drugs may increase plasma levels of Nebivolol?

Severe headache is a common side effect of Nebivolol.

What are some contraindications for using Nebivolol?

What should patients do if they miss a dose of Nebivolol?