Questions and Answers
What is the brand name for Nebivolol?
What is the generic name for Bystolic?
Nebivolol
What is Nebivolol indicated for?
For the treatment of hypertension
The recommended starting dose of Nebivolol is ______ once daily.
Signup and view all the answers
What are the available strengths of Nebivolol tablets?
Signup and view all the answers
What class of medication does Nebivolol belong to?
Signup and view all the answers
How does Nebivolol primarily act in the body?
Signup and view all the answers
Which of the following drugs may increase plasma levels of Nebivolol?
Signup and view all the answers
Severe headache is a common side effect of Nebivolol.
Signup and view all the answers
What are some contraindications for using Nebivolol?
Signup and view all the answers
What should patients do if they miss a dose of Nebivolol?
Signup and view all the answers
Study Notes
Brand Information
- Brand name: Bystolic
- Generic name: Nebivolol
Indications
- Approved for treating hypertension
Dosing Guidelines
- Starting dose: 5 mg once daily
- Potential dose increase at 2-week intervals, max 40 mg once daily
- Applicable for monotherapy or in combination therapy
- Patients with severe renal or moderate hepatic impairment: starting dose 2.5 mg once daily
Available Strengths and Dosage Forms
- Tablet strengths: 2.5 mg, 5 mg, 10 mg, 20 mg
Medication Class
- Classified as an antihypertensive agent
Pharmacology
- Primarily acts as a β1-adrenergic blocker; acts as both β1 and β2 blocker in poor metabolizers and higher doses
- Results in decreased heart rate, reduced myocardial contractibility, vasodilation, and decreased peripheral resistance
- Suppresses renin activity and diminishes tonic sympathetic outflow
Drug Interactions
- CYP2D6 inhibitors (e.g., paroxetine, fluoxetine): may elevate plasma levels
- CYP2D6 inducers: may lower plasma levels
- Use with digitalis glycosides and non-dihydropyridine calcium channel blockers (e.g., verapamil, diltiazem): risk of excessive bradycardia
- No interactions classified as risk X/D
Side Effects
- Common effects include headache, nausea, fatigue, and dizziness
- None of the side effects exceed a 10% occurrence rate
Contraindications
- Not for use in severe bradycardia, first-degree heart block, cardiogenic shock, decompensated cardiac failure, and sick sinus syndrome (without a pacemaker)
- Avoid in severe hepatic impairment and hypersensitivity to any component
- Sudden discontinuation may worsen angina, myocardial infarction, or ventricular arrhythmias
- Caution advised for bronchospastic patients
- Can mask hypoglycemic symptoms in diabetic patients
- Classified as Pregnancy Category C
Patient Counseling
- Store in a cool, dry place away from light and children
- If a dose is missed, take as soon as possible; skip if it's near next dose time—do not double doses
- Consult a physician for severe or persistent side effects
- Do not stop taking without consulting a physician
- May cause drowsiness; exercise caution in activities requiring alertness
- Diabetic patients should be aware of symptom masking
- Avoid nonprescription cold, cough, and allergy medications unless directed
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
Description
Test your knowledge on Nebivolol with these flashcards. The cards cover various aspects such as brand name, indications for use, and dosing guidelines. Enhance your understanding of this medication and its applications in treating hypertension.
