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Questions and Answers

What initiates the process of synaptic transmission at the axon terminal?

  • Decaying of the graded potential
  • Binding of neurotransmitters to receptors
  • Release of neurotransmitters from vesicles
  • Conclusion of the action potential (correct)
  • Which type of channel is primarily responsible for allowing the influx of calcium ions during neurotransmitter release?

  • Voltage-gated Na+ channels
  • Voltage-gated K+ channels
  • Ligand-gated ion channels
  • Voltage-gated Ca2+ channels (correct)
  • What effect does the high concentration of Ca2+ in the presynaptic cell have?

  • Depolarization of the postsynaptic membrane
  • Promotion of endocytosis
  • Inhibition of neurotransmitter release
  • Exocytosis of neurotransmitters (correct)
  • What is the role of neurotransmitters after they are released into the synaptic cleft?

    <p>They bind to ligand-gated ion channels on the postsynaptic membrane</p> Signup and view all the answers

    What outcome occurs if the summated graded potentials reach the neuron threshold potential?

    <p>An action potential is generated</p> Signup and view all the answers

    What is the main function of the somatic nervous system?

    <p>Control of voluntary motor action</p> Signup and view all the answers

    Which type of PNS sensory neuron is responsible for detecting changes in temperature?

    <p>Thermoreceptors</p> Signup and view all the answers

    Which part of the nervous system includes the brain and spinal cord?

    <p>Central Nervous System</p> Signup and view all the answers

    Electroreceptors are predominantly responsible for the reception of which type of stimuli?

    <p>Light, electrical, and magnetic stimuli</p> Signup and view all the answers

    What type of neurons are responsible for carrying signals from the periphery to the central nervous system?

    <p>Sensory (Afferent) neurons</p> Signup and view all the answers

    What does the autonomic nervous system control?

    <p>Involuntary actions</p> Signup and view all the answers

    Which type of receptor is specifically responsive to pain stimuli?

    <p>Nociceptors</p> Signup and view all the answers

    The peripheral nervous system primarily consists of which of the following?

    <p>Nerves branching off the central nervous system</p> Signup and view all the answers

    What occurs during repolarization of the membrane potential?

    <p>K+ ions move out of the cell</p> Signup and view all the answers

    What is hyperpolarization in the context of membrane potential?

    <p>Membrane potential becomes more negative than resting potential</p> Signup and view all the answers

    During which phase is it impossible to trigger a second action potential?

    <p>Absolute Refractory Period</p> Signup and view all the answers

    During the relative refractory period, what is the state of the Na+ channels?

    <p>Na+ channels are closed but not inactivated</p> Signup and view all the answers

    What primarily drives the repolarization of the membrane during an action potential?

    <p>Opening of voltage-gated K+ channels</p> Signup and view all the answers

    What describes the state of K+ channels during the Absolute Refractory Period?

    <p>K+ channels are open and repolarizing the membrane</p> Signup and view all the answers

    What results from voltage-gated Na+ channels closing during an action potential?

    <p>Membrane potential begins to repolarize</p> Signup and view all the answers

    Which statement is true about the refractory periods of action potentials?

    <p>The relative refractory period allows for normal action potential generation</p> Signup and view all the answers

    What role does the sodium/potassium ATPase pump play after an action potential?

    <p>It helps maintain the resting membrane potential</p> Signup and view all the answers

    Which phase could potentially lead to a state where the membrane potential is less than -70 mV?

    <p>Hyperpolarization Phase</p> Signup and view all the answers

    What structure is primarily responsible for transferring sound from the middle ear to the inner ear?

    <p>Stapes</p> Signup and view all the answers

    Which part of the ear begins the transformation of sound waves into electrical impulses?

    <p>Cochlea</p> Signup and view all the answers

    Which taste receptor cell is NOT one of the five primary taste types?

    <p>Savory</p> Signup and view all the answers

    What is the function of the tympanic membrane?

    <p>Transfers sounds from the outer ear to the middle ear</p> Signup and view all the answers

    Which structure helps the cochlea to expand and vibrate?

    <p>Round Window</p> Signup and view all the answers

    Which part of the ear is specifically responsible for carrying sound waves to the inner ear?

    <p>Ossicles</p> Signup and view all the answers

    How does the cochlea convert mechanical signals into neural signals?

    <p>Using fluid and hair cells</p> Signup and view all the answers

    What is the role of the semicircular canals in the inner ear?

    <p>Convey information about movement</p> Signup and view all the answers

    What is the primary function of olfactory receptor cells?

    <p>Receive 'smell' molecules and send signals to the olfactory cortex</p> Signup and view all the answers

    Which part of the brain do olfactory signals specifically transmit to?

    <p>Olfactory cortex</p> Signup and view all the answers

    What type of sensory information do olfactory receptor cells mainly process?

    <p>Smell (olfactory) information</p> Signup and view all the answers

    Which of the following best describes the role of the olfactory cortex?

    <p>It processes olfactory signals</p> Signup and view all the answers

    In what way do olfactory receptor cells originally interact with their environment?

    <p>By receiving 'smell' molecules</p> Signup and view all the answers

    Which of the following statements is true about olfactory receptor cells?

    <p>They transmit signals to the olfactory cortex</p> Signup and view all the answers

    What type of molecular signals do olfactory receptor cells primarily process?

    <p>Chemical signals</p> Signup and view all the answers

    What happens to the signals received by olfactory receptor cells in the brain?

    <p>They are processed and interpreted as smells.</p> Signup and view all the answers

    Which sensory system is primarily responsible for the sense of smell?

    <p>Olfactory system</p> Signup and view all the answers

    Where are olfactory receptor cells located?

    <p>In the nasal cavity</p> Signup and view all the answers

    What type of neuron is responsible for detecting painful stimuli?

    <p>Nociceptors</p> Signup and view all the answers

    Which part of the autonomic nervous system is primarily responsible for the 'fight or flight' response?

    <p>Sympathetic nervous system</p> Signup and view all the answers

    How do the preganglionic and postganglionic neurons differ in the sympathetic nervous system?

    <p>Preganglionic neurons are long and postganglionic neurons are short</p> Signup and view all the answers

    Which neurotransmitter is released by the postganglionic neuron in the sympathetic nervous system to target effector organs?

    <p>Norepinephrine or epinephrine</p> Signup and view all the answers

    What primary role does the parasympathetic nervous system serve in the body?

    <p>Relaxing the body and promoting digestion</p> Signup and view all the answers

    Which of the following effects is NOT associated with an active sympathetic nervous system?

    <p>Relaxation of muscles</p> Signup and view all the answers

    Acetylcholine is utilized as a neurotransmitter in which part of the autonomic nervous system?

    <p>Both sympathetic and parasympathetic systems</p> Signup and view all the answers

    What is the primary function of acetylcholinesterase in the autonomic nervous system?

    <p>To hydrolyze and deactivate acetylcholine</p> Signup and view all the answers

    What effect does an active parasympathetic nervous system have on heart rate?

    <p>Decreases heart rate</p> Signup and view all the answers

    Which statement about ganglia is true?

    <p>Ganglia contain synapses between preganglionic and postganglionic neurons</p> Signup and view all the answers

    Which type of sensory neurons detects changes in temperature?

    <p>Thermoreceptors</p> Signup and view all the answers

    Why is the sympathetic nervous system sometimes referred to as the 'fight or flight' system?

    <p>It activates bodily functions to escape a threat</p> Signup and view all the answers

    What physiological change is NOT induced by the sympathetic nervous system?

    <p>Increased gastrointestinal activity</p> Signup and view all the answers

    Which pathway initiates hormonal release from the adrenal medulla in the sympathetic nervous system?

    <p>Preganglionic neuron to adrenal medulla</p> Signup and view all the answers

    Study Notes

    The Neuron

    • Neurons are the functional units of the nervous system
    • Key structures include the soma (cell body), dendrites (receiving signals), axon (sending signals), axon terminals (synaptic signal transmission), axon hillock (connection between soma and axon) , myelin sheath (fatty insulation for axon, increases speed), oligodendrocytes (CNS), Schwann cells (PNS), nodes of Ranvier (gaps in myelin), and saltatory conduction (action potential jumps across nodes).

    Action Potentials: Part 1

    • Action potentials are rapid changes in membrane potential across a membrane
    • Governed by relative ion ratios in intracellular and extracellular spaces
    • Resting potential is ~-70mV maintained by Na+/K+ ATPases, which actively transport ions against their concentration gradient, requiring ATP cleavage.
    • Depolarization occurs when the membrane potential reaches -55mV threshold, voltage-gated Na+ channels open, allowing Na+ to flow into the cell.
    • Neuron threshold potential is -55 mV
    • Steps of an Action Potential: resting state, depolarization, repolarization, hyperpolarization, and return to resting state.

    Action Potentials: Part 2

    • Repolarization: voltage-gated K+ channels open, allowing K+ out of the cell, returning the membrane potential to negative values
    • Absolute refractory period: impossible to trigger a second action potential due to Na+ channels inactivation
    • Relative refractory period: very difficult to trigger a second action potential due to membrane hyperpolarization (potential below -70mV) with Na+ channels closed but not inactivated.

    Synaptic Transmission

    • Synaptic transmission is the transmission of chemical signals between neurons across a synapse
    • The synapse is the space between two neurons, including the presynaptic and postsynaptic neurons
    • Neurotransmitters (NTs) are messenger molecules released by the presynaptic neuron and received by the postsynaptic neuron at ligand-gated ion channels
    • Excitatory postsynaptic potentials (EPSPs): depolarize the membrane (open Na+ channels)
    • Inhibitory postsynaptic potentials (IPSPs): hyperpolarize the membrane (open K+ channels)
    • Summation of EPSPs and IPSPs at the axon hillock determines if an action potential is generated
    • Examples of neurotransmitters: Glutamate (main excitatory NT in the CNS), Dopamine (reward motivation), Epinephrine and Norepinephrine (fight or flight), Acetylcholine (muscle signaling).
    • Action potential finishes at the axon terminal causing voltage-gated Calcium channels to open allowing a large influx of Ca2+ into the presynaptic cell.
    • The high concentration of Ca2+ triggers exocytosis of NTs from transport vesicles
    • The NTs cross the synaptic cleft and bind to ligand-gated ion channels on the postsynaptic membrane.
    • Either an excitatory or inhibitory postsynaptic graded potential results from this interaction
    • All newly formed graded potentials summate at the axon hillock

    Central Nervous System: Part 1

    • The central nervous system (CNS) consists of the brain and spinal cord.
    • Embryonic development stages of the brain include forebrain (telencephalon and diencephalon), midbrain (mesencephalon), and hindbrain (metencephalon and myelencephalon).
    • These regions develop into specific parts of the mature brain, some examples include: forebrain -> cerebrum, midbrain -> midbrain, hindbrain -> pons, cerebellum, and medulla oblongata

    Central Nervous System: Part 2

    • The developed brain cortex has four lobes (frontal, temporal, occipital, and parietal)
    • The cerebellum coordinates movement
    • Main components of the brainstem are the midbrain, pons, medulla oblongata, and reticular formations
    • The limbic system is responsible for emotions, memory, learning, and motivation
    • Key components of the limbic system include the thalamus, hypothalamus, hippocampus, and amygdala.
    • Spinal cord is the nervous tissue that connects the brain to the body
    • Meninges are three layers of protective membrane (dura mater, arachnoid, and pia mater)

    Peripheral Nervous System: Part 1

    • The peripheral nervous system (PNS) extends from the CNS
    • PNS contains both sensory (afferent) and motor (efferent) neurons
    • Sensory neurons are associated with mechanoreceptors, nociceptors (pain), thermoreceptors, chemoreceptors, and electroreceptors.
    • Motor neurons associated with somatic nervous system; involved with voluntary actions of skeletal muscles and autonomic nervous system; involved in involuntary actions of smooth muscles, cardiac muscle, and effector organs

    Peripheral Nervous System: Part 2

    • Autonomic nervous system is divided into sympathetic and parasympathetic systems
    • Sympathetic and parasympathetic nervous systems use acetylcholine
    • Ganglia are clusters of nerve cell bodies in the PNS.

    Special Senses: Audition + Gustation

    • Audition (hearing): outer ear (takes in sound waves), middle ear (tympanic membrane transfers sound, three bony ossicles (malleus, incus, stapes for transferring and amplifying), inner ear (cochlea converting sound to neural signals via transduction)
    • Gustation (taste): taste receptor cells, signals sent to the thalamus and gustatory cortex

    Special Senses: Vision + Olfaction

    • Vision: cornea (protects and focuses light), iris and pupil (control light entering), lens (focuses the image onto the retina), retina (contains photoreceptors rods and cones (low light and color, respectively), fovea (high acuity vision), optic nerve (transmits visual signals to brain), optic disc (blind spot), sclera (protective outer layer), choroid (vascular layer between sclera and retina)
    • Olfaction (smell): olfactory receptor cells that sense smell and send signals to olfactory cortex and thalamus

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