Natural Selection and Coat Color in Mice

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What is the main focus of the lecture on genomics?

The genetic basis for phenotypic variation in closely related species

What is the purpose of a QTL analysis?

To analyze the genetic basis for phenotypic variation in closely related species

Why is the genetic basis for phenotypic variation considered limited in resolution?

Because it is not specific to individual genes

What is the significance of the differences in beak size among G.fortis and G. scandens?

It demonstrates the impact of natural selection on beak size

What does the term 'genomic basis' refer to?

Patterns in whole genome, not actually specific

How does natural selection impact beak size in G.fortis and G. scandens?

It results in differences in beak size based on environmental factors

What is the main focus of the text?

The process of natural selection and evolution.

In which habitat did the mice exhibit sand-colored coats?

White sands.

What was the purpose of studying the frequency of different EDA alleles in sticklebacks?

To determine the impact of environmental changes on allele frequency.

What does a selective sweep result in?

A decrease in genetic diversity.

What is the main difference between a hard sweep and a soft sweep?

The impact on genetic variation.

How does linkage disequilibrium affect genetic analysis?

It complicates determining associations between genes.

What does Fst measure in genetic analysis?

The genetic divergence between populations.

What is the implication of reduced genetic variation?

Increased adaptability to new environments.

What do soft sweeps mainly involve?

"Contributing to" alleles causing phenotypic effects.

What is a genetic marker?

A DNA sequence with a known location on a chromosome

What is the purpose of a QTL (Quantitative Trait Locus) experiment?

To analyze the genetic basis of complex traits and their association with genomic regions

What is the main advantage of using genetic markers in association studies?

They provide a way to track specific genomic regions associated with traits

What is the function of the EDA gene in stickleback fish?

It influences plate development and variation in stickleback fish

What is the significance of genomic association studies?

To understand the relationship between specific genomic regions and phenotypic traits

How does the QTL technique differ from traditional Mendelian genetics?

QTL technique involves mapping genes associated with complex traits, while traditional genetics studies simple traits

How do genetic markers aid in allele frequency studies?

They assist in identifying specific genomic regions responsible for allele frequency differences

What is the role of gene flow in shaping genetic variation within populations?

Gene flow leads to an increase in genetic diversity within populations

What is the significance of COL4A5 gene in studying beak length variations in birds?

It affects beak length variations among different bird species.

What does it mean when all individuals are homozygous for a specific gene?

There is no genetic variation at that locus within the population.

What does 'recombination' refer to in the context of genetics?

The exchange of genetic material between homologous chromosomes during meiosis.

What is the process of gene flow?

The transfer of genetic material from one population to another

What is the possible result of gene flow?

Hybridization between timerata and amarylsis

What does the text suggest about the gene flow process in heliconius butterflies?

They have different topology suggesting hybridization

What do the wing colour patterns in heliconius species indicate?

Hybridization

What is the main evidence for gene flow in heliconius butterflies?

Similarity in appearance

What is suggested by the hybridization between timerata and amarylsis?

Different topology indicating hybridization

What is the role of gene flow in the transfer of genetic material between populations?

The transfer of genetic material from one population to another

In what way are the genes between timerata and amarylsis different from expectations?

Different topology suggesting hybridization

What is the possible outcome when species are hybridizing?

Different topology indicating hybridization

This quiz covers the concept of natural selection in mice, focusing on the relationship between coat color and environmental factors such as sand color. It discusses classical studies, observed changes in coat color over time, and the role of selective pressure in shaping the traits of mice populations.

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