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Questions and Answers
Which of the following best describes a natural product?
Which of the following best describes a natural product?
- A compound with a molecular weight greater than 150
- A synthetic compound used in pharmaceutical drug discovery
- A chemical compound found in nature with biological activity (correct)
- A large organic compound like a protein or carbohydrate
What types of compounds are usually considered as natural products?
What types of compounds are usually considered as natural products?
- Inorganic compounds and minerals
- Synthetic compounds and macromolecules
- Naturally-occurring small organic compounds, heterocyclic compounds, and peptides (correct)
- Large organic compounds like proteins, carbohydrates, and nucleic acids
How are natural products used in pharmaceutical drug discovery and drug design?
How are natural products used in pharmaceutical drug discovery and drug design?
- To isolate large organic compounds for drug development
- As a source of chemical compounds with potential pharmacological activity (correct)
- To synthesize proteins and nucleic acids for drug testing
- As building blocks for creating synthetic compounds
What is the molecular weight range for natural products?
What is the molecular weight range for natural products?
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Study Notes
Natural Products
- A natural product is a chemical compound or substance produced by a living organism, such as a plant, animal, or microorganism.
Types of Natural Products
- Natural products can be small molecules, such as alkaloids, glycosides, and terpenes, or biological macromolecules, like proteins and polysaccharides.
- They can also include complex mixtures, like crude extracts from plants or animals.
Use in Pharmaceutical Drug Discovery and Design
- Natural products have played a significant role in the discovery of new drugs, with many medicines being derived from or inspired by natural products.
- They serve as leads for drug design, providing a starting point for optimization and modification to create new pharmaceuticals.
Molecular Weight Range
- The molecular weight range for natural products is typically between 100-2,000 Da (dalton), with most falling in the 200-500 Da range.
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