NAPLEX Mnemonics Flashcards

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Questions and Answers

Which drugs are negative chronotropes?

  • Beta blockers (correct)
  • Calcium channel blockers (correct)
  • Amiodarone (correct)
  • Digoxin (correct)

Which beta blockers are B1 selective?

  • Atenolol (correct)
  • Metoprolol (correct)
  • Esmolol (correct)
  • Bisoprolol (correct)
  • Acebutolol (correct)
  • Bystolic (correct)
  • Betaxolol (correct)

Which beta blockers come in IV form?

  • Metoprolol (correct)
  • Labetalol (correct)
  • Propranolol (correct)
  • Atenolol
  • Sotalol
  • Esmolol (correct)

Which beta blockers have intrinsic sympathomimetic activity?

<p>Pindolol (A), Acebutolol (B), Penbutolol (C)</p> Signup and view all the answers

Which beta blockers are primarily excreted through renal pathways?

<p>Nadolol (A), Sotalol (B), Atenolol (C), Labetalol (D), Bisoprolol (E)</p> Signup and view all the answers

What are the common side effects of beta blockers?

<p>Bradycardia, bronchospasm, increased lipids, decreased libido, orthostatic hypotension, conduction abnormalities, constriction of peripheral vasculature, exhaustion, emotional depression, reduced recognition of hypoglycemia.</p> Signup and view all the answers

What are the 4 treatment considerations for CHF?

<p>Diuretics, diet, digoxin (or any + inotrope), dilators.</p> Signup and view all the answers

What are the common side effects of ACE inhibitors?

<p>Cough, angioedema, hyperkalemia, taste change, orthostasis, rash, bilateral renal stenosis, leukocytosis.</p> Signup and view all the answers

What are the common side effects of amiodarone?

<p>Pulmonary toxicity, bradycardia, thyroid dysfunction, corneal micro-deposits, photosensitivity, electrolyte abnormalities.</p> Signup and view all the answers

Which medications increase lipid levels?

<p>Protease inhibitors, antipsychotics, SGLT-2 inhibitors, beta-blockers, loop diuretics, thiazides.</p> Signup and view all the answers

Which pathway is blocked by warfarin?

<p>Extrinsic pathway.</p> Signup and view all the answers

What are the colors for warfarin tablets?

<p>1 mg: pink, 2 mg: lavender, 2.5 mg: green, 3 mg: tan, 4 mg: blue, 5 mg: peach, 6 mg: teal/greenish-blue, 7.5 mg: yellow, 10 mg: white.</p> Signup and view all the answers

What medications are given for the initial management of acute coronary syndrome (ACS)?

<p>Morphine, oxygen, nitrates, aspirin, antiplatelets, beta blocker, ACE inhibitor, statin.</p> Signup and view all the answers

What are the statin dose equivalents for 38% LDL reduction?

<p>Pitavastatin = 2 mg, Rosuvastatin = 5 mg, Atorvastatin = 10 mg, Simvastatin = 20 mg, Lovastatin = 40 mg, Pravastatin = 40 mg, Fluvastatin = 80 mg.</p> Signup and view all the answers

Which statins should be given at night?

<p>Simvastatin (A), Fluvastatin (B), Lovastatin (C)</p> Signup and view all the answers

What are the major side effects / important cautions with statins?

<p>Hepatotoxicity, myopathy, increased glucose levels, ocular effects, alopecia.</p> Signup and view all the answers

Which statins are metabolized by CYP3A4?

<p>Atorvastatin (A), Lovastatin (B), Simvastatin (C)</p> Signup and view all the answers

Which statins are metabolized by CYP2C9?

<p>Rosuvastatin (A), Fluvastatin (B)</p> Signup and view all the answers

What are the generic names for the different vitamin B's?

<p>Thiamine (B1), riboflavin (B2), niacin (B3), pyridoxine (B6), folic acid (B9), cyanocobalamin (B12).</p> Signup and view all the answers

What are the common causes of high anion gap metabolic acidosis?

<p>Methanol, uremia, diabetic ketoacidosis, paraldehyde, iron/INH, lactic acidosis, ethylene glycol/EtOH, salicylate.</p> Signup and view all the answers

What is the #1 cause of hyperthyroidism?

<p>Graves Disease.</p> Signup and view all the answers

Flashcards

Negative Chronotropes

Drugs that decrease heart rate.

B1 Selective Beta Blockers

Beta blockers that selectively target B1 receptors.

Beta Blockers in IV Form

Beta Blockers available in IV formulation

Beta Blockers with Intrinsic Sympathomimetic Activity

Beta blockers that possess some agonist activity in addition to antagonist effects.

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Renally Cleared Beta Blockers

Beta blockers that are primarily cleared through the kidneys.

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Side Effects of Beta Blockers

Common side effects that arise from taking beta blockers.

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CHF Treatment Considerations

Treatment considerations that are vital when treating Congestive Heart Failure.

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Side Effects of ACE Inhibitors

Common side effects associated with ACE inhibitors.

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Side Effects of Amiodarone

Common side effects from taking amiodarone.

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Medications Increasing Lipids

Medications that are known to increase the level of lipids.

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Warfarin's Mechanism

It inhibits vitamin K epoxide reductase, affecting clotting factors II, VII, IX, and X.

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Initial Management of Acute Coronary Syndrome (ACS)

Management plan for patients who are experiencing Acute Coronary Syndrome.

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Statin Dose Equivalents

Statin doses equivalent for moderate LDL reduction.

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Statins Administered at Night

Statins that are best administered at night.

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Side Effects/Cautions with Statins

Primary side effects and cautions to be aware of when using statins.

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Statins Metabolized by CYP3A4

Statins that are metabolized by CYP3A4.

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Statins Metabolized by CYP2C9

Statins that are metabolized by CYP2C9.

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Vitamin B Complex - Generic Names

Generic names of the vitamins that make up Vitamin B complex.

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Causes of High Anion Gap Metabolic Acidosis

Common causes that are associated with high anion gap metabolic acidosis.

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Primary Cause of Hyperthyroidism

The primary reason someone may have hyperthyroidism.

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Study Notes

Negative Chronotropes

  • Key drugs include amiodarone, beta blockers, calcium channel blockers, and digoxin (ABCD).

B1 Selective Beta Blockers

  • Memorization acronym: AMEBBBA.
  • Includes atenolol, metoprolol, esmolol, bisoprolol, betaxolol, Bystolic, and acebutolol.

Beta Blockers in IV Form

  • Recognized with the acronym "MAPLES".
  • Medications are metoprolol, atenolol, propranolol, labetalol, esmolol, and sotalol.

Beta Blockers with Intrinsic Sympathomimetic Activity

  • Include acebutolol, penbutolol, and pindolol (APP).

Renally Cleared Beta Blockers

  • Significant drugs include bisoprolol, nadolol, atenolol, labetalol, and sotalol (BreNALS).

Common Side Effects of Beta Blockers

  • Remember the acronym "BLOCKER":
    • Bradycardia/bronchospasm
    • Increased lipids/decreased libido
    • Orthostatic hypotension
    • Conduction abnormalities
    • Konstriction of peripheral vasculature
    • Exhaustion/emotional depression
    • Reduced recognition of hypoglycemia

Treatment Considerations for CHF

  • Utilize the 4 D's: Diuretics, diet, digoxin (or inotropes), dilators.

Common Side Effects of ACE Inhibitors

  • Remember "CAPTOPRIL":
    • Cough
    • Angioedema
    • Hyperkalemia
    • Taste change
    • Orthostasis
    • Risk in pregnancy
    • Rash
    • Increased potassium
    • Leukocytosis (specific to captopril)

Common Side Effects of Amiodarone

  • Acronym "AMIODARONE":
    • Pulmonary toxicity/AV block
    • Iodine issues affecting TSH
    • Corneal micro-deposits
    • Drug interactions (LFT checks)
    • Photosensitivity
    • Non-PVC infusion requirements
    • Electrolyte imbalances

Medications Increasing Lipids

  • Use acronym "PAS BLT":
    • Protease inhibitors, antipsychotics, SGLT-2, beta blockers, loop diuretics, thiazides.

Warfarin's Mechanism and Monitoring

  • Blocks the extrinsic pathway, affecting factors 2, 7, 9, and 10.
  • Measured by PT/INR (prothrombin time, international normalized ratio).

Warfarin Tablet Colors

  • Mnemonic: "party like girls then bring peaches to your wedding":
    • 1 mg: pink
    • 2 mg: lavender
    • 2.5 mg: green
    • 3 mg: tan
    • 4 mg: blue
    • 5 mg: peach
    • 6 mg: teal/greenish-blue
    • 7.5 mg: yellow
    • 10 mg: white

Initial Management of Acute Coronary Syndrome (ACS)

  • Treatment acronym: MONAA BAS (morphine, oxygen, nitrates, aspirin, antiplatelets, beta blocker, ACE inhibitor, statin).
  • Avoid beta blockers in cocaine-induced myocardial infarction and NSAIDs due to CV risks.
  • Discharge acronym: NAABAS.

Statin Dose Equivalents for Moderate LDL Reduction

  • "Passionate Real Americans Simply Love Playing Football":
    • Pitavastatin = 2 mg, Rosuvastatin = 5 mg, Atorvastatin = 10 mg, Simvastatin = 20 mg, Lovastatin = 40 mg, Pravastatin = 40 mg, Fluvastatin = 80 mg.

Statins Administered at Night

  • Remember "Simply Love F*cking" for drugs: Simvastatin, Lovastatin, Fluvastatin.

Major Side Effects/Cautions with Statins

  • Use acronym "HMG-CoA":
    • Hepatotoxicity
    • Myopathy/memory loss
    • Category X in pregnancy; risk of increased glucose
    • Upper respiratory infections
    • Increased risk of cataracts
    • Ocular effects; alopecia.

Statins Metabolized by CYP3A4

  • The three drugs are Atorvastatin, Simvastatin, and Lovastatin.
  • Grapefruit juice is a major CYP3A4 inhibitor.

Statins Metabolized by CYP2C9

  • Includes Rosuvastatin and Fluvastatin.

Generic Names for Vitamin B Complex

  • Mnemonic: "The Rabbi Needs Prayer For Comfort":
    • Thiamine (B1), Riboflavin (B2), Niacin (B3), Pyridoxine (B6), Folic acid (B9), Cyanocobalamin (B12).

Common Causes of High Anion Gap Metabolic Acidosis

  • Remember the acronym "MUDPILES":
    • Methanol, uremia, DKA, paraldehyde, iron/INH, lactic acidosis, ethylene glycol/EtOH, salicylate.

Primary Cause of Hyperthyroidism

  • Graves Disease is the leading cause, noted with the phrase: "Graves caused Credence to go HYPERnova".

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