Podcast
Questions and Answers
What is the primary purpose of the reticuloendothelial system (RES)?
What is the primary purpose of the reticuloendothelial system (RES)?
- To induce aggregation of intravenously administered nanomedicines
- To produce nanoparticle stabilization through electrostatic forces
- To facilitate the absorption of drugs through the gastrointestinal tract
- To remove immune complexes from the circulation (correct)
Which of the following is NOT a route of parenteral administration?
Which of the following is NOT a route of parenteral administration?
- Subcutaneous (SC or SQ)
- Intramuscular (IM)
- Oral (correct)
- Intravenous (IV)
What is the primary mechanism by which nonionic surfactants or polymers provide steric stabilization to nanoparticles?
What is the primary mechanism by which nonionic surfactants or polymers provide steric stabilization to nanoparticles?
- By facilitating the absorption of the nanoparticles through the gastrointestinal tract
- By inducing aggregation of the nanoparticles in the high ionic strength environment of the blood
- By adsorbing onto the particle surface and producing strong repulsion between particles (correct)
- By creating a high surface charge density that induces repulsion between particles
Why might intravenously administered nanomedicines be prone to aggregation?
Why might intravenously administered nanomedicines be prone to aggregation?
Which of the following is NOT a component of the reticuloendothelial system (RES)?
Which of the following is NOT a component of the reticuloendothelial system (RES)?
What is the primary function of electrostatic stabilization of nanoparticles?
What is the primary function of electrostatic stabilization of nanoparticles?
Which of the following statements about monocytes is correct?
Which of the following statements about monocytes is correct?
Which of the following is NOT a function of macrophages?
Which of the following is NOT a function of macrophages?
Which of the following factors does NOT influence the opsonization determinant of nanoparticles?
Which of the following factors does NOT influence the opsonization determinant of nanoparticles?
What is the primary strategy used to impart 'stealth characteristics' to nanocarriers, allowing them to evade immune recognition?
What is the primary strategy used to impart 'stealth characteristics' to nanocarriers, allowing them to evade immune recognition?
Which of the following is an example of a tissue-resident macrophage?
Which of the following is an example of a tissue-resident macrophage?
