36 Questions
What is the primary goal of using nanotechnology in medicine?
Achieving highly specific drug targeting and delivery
What is the comparative scale of a 1 nm marble to a 1 meter distance?
A 1 meter distance would be the size of the Earth
What is the primary challenge when using nanoparticles as a carrier in formulations?
The potential adverse effects of residual material
What is the main advantage of using nanotechnology in medicine?
Targeted drug delivery to the site of disease
What is the purpose of using nanoparticles as a therapeutic agent?
To deliver therapeutic agents to specific cells or tissues
What is the role of nanotechnology in reducing toxicity while maintaining therapeutic effects?
By delivering medications directly to the site of disease
Which type of lipid vesicles contain phospolipids and alcohol in relatively high concentrations?
Ethosomes
What is the unique characteristic of Cubosomes?
Cubic shape
Which inorganic particles are known for their function of conjugation to target-specific ligands?
Silica
What is the primary architectural feature of Dendrimers?
Branching monomers
Which nanoparticle type is commonly associated with a concern regarding stability due to hydrophobic surfaces?
Magnetic NP
What is the primary function of Virosomes?
Delivery of nucleic-acid free viral particles
What distinguishes Cochleates from other lipid vesicles?
Cigar-shaped
What sets apart Layered Double Hydroxide nanoparticles from other inorganic particles?
Layered structure
What is the most common material used in Metal-based nanoparticles?
Gold NPs
How do Dendrimers differ from most linear polymers in terms of control over their properties?
They can be incrementally grown in nm steps
What is one of the strategies mentioned in the text for increasing blood circulation time of nanoparticles?
Secondary reaction on grafted groups
What is unique about nanotubes and nanohorns in terms of their architecture?
They have layers of graphene
How can the biocompatibility of carbon nanotubes be improved according to the text?
By covalent anchoring of dendrimers
Which of the following is NOT mentioned as a mechanism for drug immobilization in carbon nanocarriers?
Direct injection into the bloodstream
What is the advantage of encapsulation over other mechanisms for drug immobilization in carbon nanocarriers according to the text?
Protection from degradation during transport
Which type of nanoparticles provides sustained release of drugs from the polymeric matrix according to the text?
Polymer-coated nanoparticles
What potential issue may arise due to slowly degradable or nondegradable nanoparticles at the site of delivery according to the text?
Accumulation resulting in chronic inflammation
What can cationic nanoparticles cause according to the text?
Hemolysis and blood clotting
What effect have silica nanoparticles shown according to the text at increasing doses and exposure times?
Increased oxidative stress
What effect have carbon based nanoparticles shown on macrophage cell lines according to the text?
Necrosis or apoptosis
Which nanoparticle-based product is known for its flexibility and ability to permeate intact through the dermal barrier?
Transfersome
Which type of nanoparticle is known for its biodegradable and biocompatible properties, as well as its potential for surface modification and functionalization with different ligands?
Polymeric nanoparticles
Which type of targeting strategy exploits the anatomical differences between normal and diseased tissues to deliver drugs?
Passive targeting
Which nanoparticle-based product is known for its ability to improve the stability of hydrophobic drugs and reduce adverse effects as a consequence of favored accumulation at target sites?
Polymeric nanoparticles
Which nanoparticle-based product is known for its ability to maintain higher intracellular drug levels than in cells treated with drug in solution or with unconjugated nanoparticles?
Transferrin-conjugated paclitaxel-loaded nanoparticles
Which nanoparticle-based product is known for its ability to improve the circulation time of drugs and is approved for the treatment of advanced ovarian cancer, metastatic breast cancer, and AIDS-related Kaposi's sarcoma?
DOXIL
Which type of nanoparticle-based product is known for its lower cost and higher chemical stability than its naturally occurring phospholipid counterparts?
Niosomes
Which type of targeting strategy requires conjugation of receptor-specific ligands that can promote site-specific targeting?
Active targeting
Which type of nanoparticle-based product is known for its ability to improve biodistribution and pharmacokinetics, resulting in improved efficacy and reduced adverse effects as a consequence of favored accumulation at target sites?
Polymeric nanoparticles
Which type of nanoparticle-based product is known for its ability to reduce toxicity using biocompatible nanomaterials and efficiently penetrate across barriers through small capillaries into individual cells?
Polymeric nanoparticles
Explore the applications of nanotechnology in medicine, targeting strategies, and examples of nanoparticles. Learn about the history of nanotechnology, coined by Norio Taniguchi in 1974, and understand the scale of nanometers in comparison to everyday objects like a sheet of newspaper or a marble.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
