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Questions and Answers

What are risks for pulmonary embolism?

  • After surgery (correct)
  • Long car ride (correct)
  • Hypercoagulable state (cancer, nephrotic) (correct)
  • None of the above
  • What are the indicators of STEMI on ECG?

    2mm ST elevation, T wave inversion after 6hrs, Q waves last forever, new LBBB

    What leads are associated with localized infarcts?

    V1-4 for anterior (LAD), I aVL V4-6 for lateral (Circumflex), II III aVF for inferior (RCA), V4 on right side ECG for RV (RCA)

    What are emergency reperfusion options?

    <p>Cath lab, thrombolytics within 6 hours</p> Signup and view all the answers

    What are the symptoms of RV infarct?

    <p>Low BP, tachycardia, clear lungs, JVD, no pulsus paradoxus</p> Signup and view all the answers

    What is the workup after EKG for STEMI?

    <p>Cardiac enzyme tests</p> Signup and view all the answers

    What is the diagnosis for normal ECG with elevated cardiac enzymes?

    <p>NSTEMI</p> Signup and view all the answers

    What are the three cardiac enzymes?

    <p>Myoglobin, CK-MB, Troponin I</p> Signup and view all the answers

    What is included in NSTEMI acute treatment?

    <p>Morphine, O2, Nitrites, ASA/clopidogrel, coronary angiography within 48 hours</p> Signup and view all the answers

    What is the first treatment option for STEMI?

    <p>PCI with stenting</p> Signup and view all the answers

    What medications should be included in NSTEMI discharge prescriptions?

    <p>Beta-blocker, ACEI if CHF or LV dysfunction, Statin, Heparin, nitrates</p> Signup and view all the answers

    What leads to a diagnosis of unstable angina?

    <p>Normal cardiac enzyme x 3 indicates unstable angina if both tests are negative.</p> Signup and view all the answers

    What to avoid before an exercise EKG?

    <p>Beta-blocker, CCB</p> Signup and view all the answers

    What are contraindications to exercise stress tests?

    <p>Old LBBB, baseline ST elevation, on Digoxin</p> Signup and view all the answers

    What medications are used for a chemical stress test?

    <p>Dobutamine, adenosine, thallium-dipyridamole</p> Signup and view all the answers

    What needs to be avoided before MUGA?

    <p>Caffeine, theophylline</p> Signup and view all the answers

    What is the acute treatment for unstable angina?

    <p>Beta-blocker, nitrate, ASA</p> Signup and view all the answers

    What is the most common cause of death post-MI?

    <p>Arrhythmias</p> Signup and view all the answers

    What murmur is associated with papillary muscle rupture post-MI?

    <p>Holosystolic murmur radiating to axilla</p> Signup and view all the answers

    What causes acute severe hypotension post-MI?

    <p>Ventricular free wall rupture</p> Signup and view all the answers

    What indicates a 'step up' in oxygen from RA to RV post-MI?

    <p>Ventricular septal rupture</p> Signup and view all the answers

    What is indicated by persistent ST elevation one month later post-MI?

    <p>Ventricular wall aneurysm</p> Signup and view all the answers

    What does 'Cannon A-waves' indicate?

    <p>AV-dissociation, either V-fib or 3rd degree heart block</p> Signup and view all the answers

    What is Dressler's syndrome?

    <p>Autoimmune pericarditis post-MI, treated with NSAIDs and ASA.</p> Signup and view all the answers

    What characterizes pericarditis in a young, healthy patient?

    <p>Worsens with inspiration, better with leaning forward, friction rub.</p> Signup and view all the answers

    What condition presents with chest pain that worsens with palpation?

    <p>Costochondriasis</p> Signup and view all the answers

    What characterizes chest pain with a vague history of viral infection?

    <p>More details needed to diagnose, potentially pericarditis.</p> Signup and view all the answers

    Study Notes

    Risks for Pulmonary Embolism (PE)

    • Increased risk after surgery, long car rides, or conditions leading to hypercoagulability (e.g., cancer, nephrotic syndrome).

    STEMI Indicators on ECG

    • 2mm ST elevation observed immediately.
    • T wave inversions appear within 6 hours and can last for years.
    • Q waves remain permanently.
    • New left bundle branch block (LBBB) with wide, flat QRS complexes can indicate STEMI.
    • Anterior infarct associated with the Left Anterior Descending artery (LAD), diagnosed with leads V1-V4.
    • Lateral infarct tied to the Circumflex artery, seen in leads I, aVL, V4-V6.
    • Inferior infarct linked to the Right Coronary Artery (RCA) with leads II, III, aVF.
    • Right Ventricular (RV) infarct noted with RCA, leads V4 on right side ECG.

    Emergency Reperfusion Options

    • Options include catheterization in the cath lab and thrombolytics, effective within 6 hours.
    • Contraindications include active bleeding, history of hemorrhagic stroke, and recent closed head trauma.

    Right Ventricular (RV) Infarct Presentation

    • Symptoms include low blood pressure, tachycardia, clear lung sounds, and jugular venous distention (JVD).
    • Absence of pulsus paradoxus.
    • Treatment involves vigorous fluid resuscitation to increase preload; nitroglycerin is contraindicated.

    STEMI Workup After ECG

    • Confirmation through cardiac enzyme testing.

    Normal ECG with Elevated Cardiac Enzymes

    • Diagnosis of NSTEMI (Non-ST Elevation Myocardial Infarction).
    • Repeat enzyme tests every 8 hours for 3 cycles to observe trends.

    Cardiac Enzyme Markers

    • Myoglobin: Rises first, peaks at 2 hours, normal by 24 hours.
    • CK-MB: Rises 4-8 hours, peaks at 24 hours, normal by 72 hours.
    • Troponin I: Rises 3-5 hours, peaks at 24-48 hours, normal by 7-10 days.

    NSTEMI Acute Treatment

    • Immediate management includes morphine, oxygen, nitrates, and ASA/clopidogrel.
    • Coronary angiography should be performed within 48 hours.

    Primary Treatment for STEMI and NSTEMI

    • First-line treatment involves percutaneous coronary intervention (PCI) with stenting.
    • CABG indicated in cases such as significant left main disease, multivessel disease, or persistent symptoms despite treatment.

    NSTEMI Discharge Medications

    • Post-discharge regimen includes beta-blockers (e.g., Metoprolol), ACE inhibitors for CHF or LV dysfunction, statins, and heparin during hospitalization.

    Criteria for Unstable Angina

    • Diagnosis confirmed with three normal cardiac enzyme tests; if both are negative, it indicates unstable angina.

    Unstable Angina Workup Process

    • Tests include exercise ECG, exercise echocardiogram, chemical stress tests (adenosine/dobutamine), and MUGA scan for heart perfusion.
    • Positive results warrant coronary angiography.

    Pre-Exercise ECG Preparations

    • Avoid beta-blockers and calcium channel blockers (CCB) prior to stress testing.

    Contraindications for Exercise Stress Testing

    • Includes old LBBB, baseline ST elevation, and patients on digoxin.

    Medications for Chemical Stress Testing

    • Utilizes dobutamine, adenosine, and thallium-dipyridamole to enhance coronary blood flow during testing.

    Pre-MUGA Considerations

    • Caffeine and theophylline should be avoided before undergoing a MUGA scan.

    Acute Treatment for Unstable Angina

    • Immediate management involves beta-blockers, nitrates, and aspirin (ASA).

    Post-MI Complications Overview

    • Arrhythmias, particularly ventricular fibrillation (VF), are the most common cause of death after a myocardial infarction.

    Post-MI Complications: Papillary Muscle Rupture

    • Manifests 5-7 days post-MI as a holosystolic murmur indicative of mitral regurgitation radiating to the axilla.

    Severe Hypotension After MI

    • Acute hypotension can arise from ventricular free wall rupture, indicating a critical condition.

    "Step Up" in Oxygen Saturation

    • Observed in ventricular septal rupture when there is a higher oxygen concentration in the right atrium compared to the right ventricle.

    Persistent ST Elevation Post-MI

    • Around one month later, may indicate a ventricular wall aneurysm accompanied by systolic mitral regurgitation murmur.

    Cannon A-Waves and JVP Findings

    • Associated with AV dissociation, potentially due to ventricular fibrillation or third-degree heart block.

    Delayed Pleuritic Chest Pain Post-MI

    • Occurring 5-10 weeks later may suggest Dressler's syndrome, an autoimmune form of pericarditis, treatable with NSAIDs and ASA.

    Pericarditis in Young Patients

    • Symptoms include chest pain exacerbated by inspiration, relieved by leaning forward, often displaying diffuse ST elevation on ECG; treated with NSAIDs.

    Costochondritis Presentation

    • Characterized by chest pain that worsens upon palpation, common in young, healthy individuals.

    Vague Chest Pain with Viral History

    • Indication of potential myocarditis or other viral-related cardiac conditions requiring further evaluation.

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