5 Questions
What is myocarditis?
A condition where the muscular walls of the heart become inflamed
What are some common causes of myocarditis in children?
Viral infections
Which of the following viruses is NOT commonly involved in causing myocarditis in children?
Hepatitis A virus
What can activate the innate immune response in myocarditis?
Death of infected cells
What is the role of Coxsackie-adenovirus receptor in myocarditis pathogenesis?
It activates the innate immune response
Study Notes
Myocarditis Overview
- Myocarditis is an inflammatory disease of the myocardium, the heart muscle.
Causes of Myocarditis in Children
- Common causes of myocarditis in children include viral infections, specifically:
- Coxsackievirus
- Adenovirus
- Parvovirus
- Influenza virus
- Epstein-Barr virus
- Note: Enterovirus is NOT commonly involved in causing myocarditis in children.
Innate Immune Response
- The innate immune response in myocarditis can be activated by:
- Recognition of viral pathogen-associated molecular patterns (PAMPs)
- Activation of pattern recognition receptors (PRRs)
Coxsackie-Adenovirus Receptor
- The Coxsackie-adenovirus receptor (CAR) plays a crucial role in myocarditis pathogenesis by:
- Facilitating viral entry into cardiac cells
- Mediating viral-induced inflammation and cardiac damage
Learn about myocarditis, a condition where the heart muscles become inflamed and can lead to poor heart function. Explore its causes, which include infections, medications, chemicals, and certain diseases. Understand the common viral infections that can cause myocarditis in children.
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