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Questions and Answers
What is myocarditis?
What is myocarditis?
- A condition where the muscular walls of the heart become enlarged
- A condition where the blood vessels of the heart become blocked
- A condition where the heart beats irregularly
- A condition where the muscular walls of the heart become inflamed (correct)
What are some common causes of myocarditis in children?
What are some common causes of myocarditis in children?
- Viral infections (correct)
- Excessive exercise
- Bacterial infections
- Genetic predisposition
Which of the following viruses is NOT commonly involved in causing myocarditis in children?
Which of the following viruses is NOT commonly involved in causing myocarditis in children?
- Parvovirus
- Adenovirus
- Influenza virus
- Hepatitis A virus (correct)
What can activate the innate immune response in myocarditis?
What can activate the innate immune response in myocarditis?
What is the role of Coxsackie-adenovirus receptor in myocarditis pathogenesis?
What is the role of Coxsackie-adenovirus receptor in myocarditis pathogenesis?
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Study Notes
Myocarditis Overview
- Myocarditis is an inflammatory disease of the myocardium, the heart muscle.
Causes of Myocarditis in Children
- Common causes of myocarditis in children include viral infections, specifically:
- Coxsackievirus
- Adenovirus
- Parvovirus
- Influenza virus
- Epstein-Barr virus
- Note: Enterovirus is NOT commonly involved in causing myocarditis in children.
Innate Immune Response
- The innate immune response in myocarditis can be activated by:
- Recognition of viral pathogen-associated molecular patterns (PAMPs)
- Activation of pattern recognition receptors (PRRs)
Coxsackie-Adenovirus Receptor
- The Coxsackie-adenovirus receptor (CAR) plays a crucial role in myocarditis pathogenesis by:
- Facilitating viral entry into cardiac cells
- Mediating viral-induced inflammation and cardiac damage
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