Podcast
Questions and Answers
It pertains to the prevention of Blood loss.
It pertains to the prevention of Blood loss.
Causes: local myogenic spasm, autacoids (Thromboxane A2), and nervous
reflexes.
Causes: local myogenic spasm, autacoids (Thromboxane A2), and nervous reflexes.
The cells responsible are the Platelets.
The cells responsible are the Platelets.
Blood Coagulation
Process which is initiated by either a traumatized
tissue (A. extrinsic way) or the platelets that have
been exposed to a traumatized vessel (B. intrinsic
way) to stimulate the prothrombin activator; this in
turn, triggers a series of processes (an example of a
positive feedback mechanism which is beneficial to
the body)
Blood Coagulation Process which is initiated by either a traumatized tissue (A. extrinsic way) or the platelets that have been exposed to a traumatized vessel (B. intrinsic way) to stimulate the prothrombin activator; this in turn, triggers a series of processes (an example of a positive feedback mechanism which is beneficial to the body)
Signup and view all the answers
The platelets that have been exposed to a traumatized vessel.
The platelets that have been exposed to a traumatized vessel.
Signup and view all the answers
A traumatized tissue
A traumatized tissue
Signup and view all the answers
It stimulates the prothrombin activator (it started from tissue trauma/damaged vessel)
It stimulates the prothrombin activator (it started from tissue trauma/damaged vessel)
Signup and view all the answers
It stimulates prothrombin activator and it started from the traumatized blood cells (platelets) upon contact with exposed collagen in the damaged vessel.
It stimulates prothrombin activator and it started from the traumatized blood cells (platelets) upon contact with exposed collagen in the damaged vessel.
Signup and view all the answers
Deficiency in the number of platelets.
Deficiency in the number of platelets.
Signup and view all the answers
Any Liver diseases that destroy the liver hepatocytes; these tissues
are responsible for the production of _____ and _____.
Any Liver diseases that destroy the liver hepatocytes; these tissues are responsible for the production of _____ and _____.
Signup and view all the answers
Accidental ingestion of anticoagulants like _____ and _____
(poisoning).
Accidental ingestion of anticoagulants like _____ and _____ (poisoning).
Signup and view all the answers
Individual suffering from bleeding tendency (Hemophilia) due
deficiency of Anti _____ factor.
Individual suffering from bleeding tendency (Hemophilia) due deficiency of Anti _____ factor.
Signup and view all the answers
Blood coagulation process requires the use of several substances called
_____ (which hastens the occurrence of the process) and in contrast, it is hindered by substances called _____.
Blood coagulation process requires the use of several substances called _____ (which hastens the occurrence of the process) and in contrast, it is hindered by substances called _____.
Signup and view all the answers
Examples of pro coagulants are listed below except:
Examples of pro coagulants are listed below except:
Signup and view all the answers
Anticoagulants are classified into:
Anticoagulants are classified into:
Signup and view all the answers
These are the substances normally present in the body that hinders the occurrence of coagulation process
Examples: Heparin, Antithrombin III, prostaglandins, Heparin co-factor, Protein C
These are the substances normally present in the body that hinders the occurrence of coagulation process Examples: Heparin, Antithrombin III, prostaglandins, Heparin co-factor, Protein C
Signup and view all the answers
These are the substances that can be bought in the market and commonly used in the laboratory. Examples: Heparin (both physiological and commercially available) Coumarin, Warfarin, EDTA, Ca EDT
These are the substances that can be bought in the market and commonly used in the laboratory. Examples: Heparin (both physiological and commercially available) Coumarin, Warfarin, EDTA, Ca EDT
Signup and view all the answers
Initiated by Fibroblast Stimulating Factor/Vascular Endothelial Growth Factor released by platelets.
Initiated by Fibroblast Stimulating Factor/Vascular Endothelial Growth Factor released by platelets.
Signup and view all the answers
They are the third group of blood cells that originate from the Megakaryocytes. They are regarded as the FRAGMENTS of MEGAKARYOCYTES (regarded as the 7th type of WBC).
They are the third group of blood cells that originate from the Megakaryocytes. They are regarded as the FRAGMENTS of MEGAKARYOCYTES (regarded as the 7th type of WBC).
Signup and view all the answers
Physical Properties of Platelets:
They are minute cells formed from the Megakaryocytes.
Physical Properties of Platelets: They are minute cells formed from the Megakaryocytes.
Signup and view all the answers
Physical Properties of Platelets:
They are called the "Fragments of Megakaryocytes".
Physical Properties of Platelets: They are called the "Fragments of Megakaryocytes".
Signup and view all the answers
Physical Properties of Platelets:
Life span in the circulation = 20 days
Physical Properties of Platelets: Life span in the circulation = 20 days
Signup and view all the answers
Physical Properties of Platelets:
Oval or coma-shaped cells.
Physical Properties of Platelets: Oval or coma-shaped cells.
Signup and view all the answers
Physical Properties of Platelets:
Pilable cells
Physical Properties of Platelets: Pilable cells
Signup and view all the answers
Physical Properties of Platelets:
Concentration – varies in different species
Physical Properties of Platelets: Concentration – varies in different species
Signup and view all the answers
Approximately = 150000- 200,000 per microliter of blood (normal values vary in different animals).
Approximately = 150000- 200,000 per microliter of blood (normal values vary in different animals).
Signup and view all the answers
Chemical/Functional Properties of Platelets:
They have contractile structures called Actin and Myosin molecules and
Thrombosthenin.
Chemical/Functional Properties of Platelets: They have contractile structures called Actin and Myosin molecules and Thrombosthenin.
Signup and view all the answers
Chemical/Functional Properties of Platelets:
They have residual of ER and Golgi apparatus that can synthesize various
enzymes and store large quantities of Iron.
Chemical/Functional Properties of Platelets: They have residual of ER and Golgi apparatus that can synthesize various enzymes and store large quantities of Iron.
Signup and view all the answers
Chemical/Functional Properties of Platelets
They have Mitochondria (produce ATP).
Chemical/Functional Properties of Platelets They have Mitochondria (produce ATP).
Signup and view all the answers
Chemical/Functional Properties of Platelets:
They have enzymes that synthesize Prostaglandins that causes vascular and
tissue reactions.
Chemical/Functional Properties of Platelets: They have enzymes that synthesize Prostaglandins that causes vascular and tissue reactions.
Signup and view all the answers
Chemical/Functional Properties of Platelets:
They release Fibrinogen-Stabilizing Factors
Chemical/Functional Properties of Platelets: They release Fibrinogen-Stabilizing Factors
Signup and view all the answers
Chemical/Functional Properties of Platelets:
They release vascular “Endothelial Cell Growth Factor”
Chemical/Functional Properties of Platelets: They release vascular “Endothelial Cell Growth Factor”
Signup and view all the answers
Chemical/Functional Properties of Platelets:
They have Glycoprotein on their surfaces. Glycoprotein repulses adherence of
platelets to normal endothelium but causes adherence to damaged/ injure
endothelial cells.
Chemical/Functional Properties of Platelets: They have Glycoprotein on their surfaces. Glycoprotein repulses adherence of platelets to normal endothelium but causes adherence to damaged/ injure endothelial cells.
Signup and view all the answers
Chemical/Functional Properties of Platelets:
They release Bilipids that activate multiple stages of blood clotting
process.
Chemical/Functional Properties of Platelets: They release Bilipids that activate multiple stages of blood clotting process.
Signup and view all the answers
