Podcast
Questions and Answers
What is the ultimate source of variation and novelty in evolution?
What is the ultimate source of variation and novelty in evolution?
In eukaryotes, where can mutations occur but are not inherited?
In eukaryotes, where can mutations occur but are not inherited?
Which type of mutation usually leads to a dominant gain of function?
Which type of mutation usually leads to a dominant gain of function?
What does SNP stand for in genetics?
What does SNP stand for in genetics?
Signup and view all the answers
Which type of mutation refers to either an insertion or deletion?
Which type of mutation refers to either an insertion or deletion?
Signup and view all the answers
What type of mutation involves a change in the location of nucleotides?
What type of mutation involves a change in the location of nucleotides?
Signup and view all the answers
What is the repair pathway involved in fixing double strand breaks in DNA?
What is the repair pathway involved in fixing double strand breaks in DNA?
Signup and view all the answers
Which type of radiation can cause T-T dimerization leading to deletions or insertions in DNA?
Which type of radiation can cause T-T dimerization leading to deletions or insertions in DNA?
Signup and view all the answers
What type of agents can substitute for purines or pyrimidines during nucleic acid biosynthesis?
What type of agents can substitute for purines or pyrimidines during nucleic acid biosynthesis?
Signup and view all the answers
Which repair mechanism involves adding nucleotides to fill in gaps after alignment of DNA ends?
Which repair mechanism involves adding nucleotides to fill in gaps after alignment of DNA ends?
Signup and view all the answers
Which mutagenic agent reacts with nucleic acids to cause mutations?
Which mutagenic agent reacts with nucleic acids to cause mutations?
Signup and view all the answers
What is the high-energy source that can knock off electrons and cause mutations in DNA?
What is the high-energy source that can knock off electrons and cause mutations in DNA?
Signup and view all the answers
Which process is responsible for the base change due to the repositioning of hydrogen in a DNA molecule?
Which process is responsible for the base change due to the repositioning of hydrogen in a DNA molecule?
Signup and view all the answers
What type of mutation occurs due to hydrolysis of a purine (A or G) in a DNA molecule?
What type of mutation occurs due to hydrolysis of a purine (A or G) in a DNA molecule?
Signup and view all the answers
Which mutation type results from the removal of an amine group in either C or A, leading to U or hypoxanthine formation, respectively?
Which mutation type results from the removal of an amine group in either C or A, leading to U or hypoxanthine formation, respectively?
Signup and view all the answers
Which mutation arises from denaturation of the new DNA strand during replication, followed by renaturation in a different location?
Which mutation arises from denaturation of the new DNA strand during replication, followed by renaturation in a different location?
Signup and view all the answers
What is the process that allows DNA replication past DNA lesions with low fidelity on undamaged templates?
What is the process that allows DNA replication past DNA lesions with low fidelity on undamaged templates?
Signup and view all the answers
What is the term for the error-prone replication bypass process that often results in the insertion of wrong bases?
What is the term for the error-prone replication bypass process that often results in the insertion of wrong bases?
Signup and view all the answers
What type of mutations result from intercalating agents?
What type of mutations result from intercalating agents?
Signup and view all the answers
Which repair mechanism involves the excision of damaged DNA by a light-dependent enzyme?
Which repair mechanism involves the excision of damaged DNA by a light-dependent enzyme?
Signup and view all the answers
What is the main activity of DNA polymerase I in excision repair?
What is the main activity of DNA polymerase I in excision repair?
Signup and view all the answers
Which type of mutation can alkylating agents cause?
Which type of mutation can alkylating agents cause?
Signup and view all the answers
What is the result of oxidative damage by oxygen radicals on DNA?
What is the result of oxidative damage by oxygen radicals on DNA?
Signup and view all the answers
Which enzyme is responsible for repairing mismatched bases in DNA?
Which enzyme is responsible for repairing mismatched bases in DNA?
Signup and view all the answers
What type of mutation causes a change in amino acid transcribed and alters protein function?
What type of mutation causes a change in amino acid transcribed and alters protein function?
Signup and view all the answers
Which type of mutation does NOT alter protein function and results in a shift in the reading frame?
Which type of mutation does NOT alter protein function and results in a shift in the reading frame?
Signup and view all the answers
At a twofold degenerate site, how many possible changes are nonsynonymous?
At a twofold degenerate site, how many possible changes are nonsynonymous?
Signup and view all the answers
Which type of mutation results in no change in the amino acid transcribed?
Which type of mutation results in no change in the amino acid transcribed?
Signup and view all the answers
What is the effect of a nonsense mutation?
What is the effect of a nonsense mutation?
Signup and view all the answers
What can cause a frameshift mutation?
What can cause a frameshift mutation?
Signup and view all the answers
