18 Questions
What type of mutation results from the deamination of cytosine?
Transition mutation
Which of the following is a spontaneous mechanism that can lead to mutations?
Tautomeric shifts in nitrogenous bases
What is the potential consequence of the formation of an abasic (AP) site in DNA?
It can lead to a frameshift mutation if not repaired
Which of the following is a physical mutagen?
UV radiation
What is the purpose of the Ames test?
To determine the mutagenic potential of chemicals
Which of the following statements about tautomeric shifts is correct?
They can lead to abnormal base pairing during DNA replication
Which of the following is NOT a type of spontaneous mutation?
Exposure to UV radiation
The Ames Test is used to detect:
Mutagenic potential of chemicals
Which of the following is a result of deamination of cytosine?
Conversion of cytosine to uracil
Which of the following is NOT a mutagen?
DNA polymerase
Tautomeric shifts in DNA can lead to:
Mismatched base pairing
Which of the following is a type of hydrolysis reaction that can cause spontaneous mutations?
Depurination
What is the primary purpose of the Ames test?
To identify chemicals that can cause reversion of a histidine auxotrophic mutation in Salmonella
Which of the following is a type of spontaneous mutation that can result from the deamination of cytosine?
Transition
What is a potential consequence of the formation of an abasic (AP) site in DNA?
It can cause replication to stall
What is the potential consequence of tautomeric shifts in DNA?
They can lead to spontaneous mutations
Which of the following is an example of a spontaneous mechanism that can lead to mutations?
Deamination of cytosine
What is the purpose of the modified Ames test?
To assay for the mutagenic properties of chemicals processed through the liver
Explore the different types of mutations such as premature stop codon, pseudogene, inversion, and duplication, as well as the mechanisms for mutations including spontaneous and induced mutations. Learn how these genetic changes can impact genes and protein products.
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