Mutation Information: Types and Mechanisms
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Questions and Answers

What type of mutation results from the deamination of cytosine?

  • Transition mutation (correct)
  • Nonsense mutation
  • Transversion mutation
  • Frameshift mutation

    • Which of the following is a spontaneous mechanism that can lead to mutations?

  • Treatment with mustard gas
  • Exposure to high temperatures
  • Exposure to X-rays
  • Tautomeric shifts in nitrogenous bases (correct)

    • What is the potential consequence of the formation of an abasic (AP) site in DNA?

  • It can result in a premature stop codon
  • It can lead to a frameshift mutation if not repaired (correct)
  • It can cause a transversion mutation
  • It can cause a gene duplication

    • Which of the following is a physical mutagen?

    <p>UV radiation</p> Signup and view all the answers

    What is the purpose of the Ames test?

    <p>To determine the mutagenic potential of chemicals</p> Signup and view all the answers

    Which of the following statements about tautomeric shifts is correct?

    <p>They can lead to abnormal base pairing during DNA replication</p> Signup and view all the answers

    Which of the following is NOT a type of spontaneous mutation?

    <p>Exposure to UV radiation</p> Signup and view all the answers

    The Ames Test is used to detect:

    <p>Mutagenic potential of chemicals</p> Signup and view all the answers

    Which of the following is a result of deamination of cytosine?

    <p>Conversion of cytosine to uracil</p> Signup and view all the answers

    Which of the following is NOT a mutagen?

    <p>DNA polymerase</p> Signup and view all the answers

    Tautomeric shifts in DNA can lead to:

    <p>Mismatched base pairing</p> Signup and view all the answers

    Which of the following is a type of hydrolysis reaction that can cause spontaneous mutations?

    <p>Depurination</p> Signup and view all the answers

    What is the primary purpose of the Ames test?

    <p>To identify chemicals that can cause reversion of a histidine auxotrophic mutation in Salmonella</p> Signup and view all the answers

    Which of the following is a type of spontaneous mutation that can result from the deamination of cytosine?

    <p>Transition</p> Signup and view all the answers

    What is a potential consequence of the formation of an abasic (AP) site in DNA?

    <p>It can cause replication to stall</p> Signup and view all the answers

    What is the potential consequence of tautomeric shifts in DNA?

    <p>They can lead to spontaneous mutations</p> Signup and view all the answers

    Which of the following is an example of a spontaneous mechanism that can lead to mutations?

    <p>Deamination of cytosine</p> Signup and view all the answers

    What is the purpose of the modified Ames test?

    <p>To assay for the mutagenic properties of chemicals processed through the liver</p> Signup and view all the answers

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