Muscle Standard
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Questions and Answers

Muscle tissue, one of the four principal types of tissue, consists chiefly of muscle cells that are highly specialized for:

  • Contraction (correct)
  • Lifting
  • Conduction
  • Shortening
  • Which of the following is NOT a type of muscle tissue?

  • Smooth
  • Skeletal
  • Cardiac
  • Vascular (correct)
  • Skeletal muscle tissue forms skeletal muscles, organs that also contain each of the following, EXCEPT:

  • Bones (correct)
  • Nerves
  • Connective tissues
  • Blood vessels
  • Each cell in skeletal muscle tissue is a:

    <p>Single muscle fibre</p> Signup and view all the answers

    Skeletal muscles perform each of the following functions, EXCEPT:

    <p>Moves contents of the digestive tract</p> Signup and view all the answers

    During development, groups of ______________ fuse together to form individual skeletal muscle fibres.

    <p>myoblasts</p> Signup and view all the answers

    What is another name for the cell membrane of a muscle fibre?

    <p>Sarcolemma</p> Signup and view all the answers

    Electrical impulses (action potentials) travel down _____________ into the muscle cells to efficiently trigger muscle fibre contraction.

    <p>Transverse (T) tubules</p> Signup and view all the answers

    What is the name for the cylindrical structures, which can actively shorten and thus are responsible for skeletal muscle fibre contraction?

    <p>Myofibrils</p> Signup and view all the answers

    Myofibrils consist of bundles of ______________, which are protein filaments composed primarily of thin filaments and thick filaments.

    <p>myofilaments</p> Signup and view all the answers

    The ______________________ is an intracellular membrane complex, containing Ca2+ ions.

    <p>Sarcoplasmic reticulum (SR)</p> Signup and view all the answers

    _____________ ions are released into the sarcoplasm on receiving electrical signals.

    <p>Calcium (Ca2+)</p> Signup and view all the answers

    Myofilaments are organized into repeating functional units called _______________________ and interactions between the thick and thin filaments of these functional units are responsible for muscle contraction.

    <p>sarcomeres</p> Signup and view all the answers

    A sarcomere contains each of the following except:

    <p>Proteins that regulate generation of thick and thin filaments</p> Signup and view all the answers

    Visually, when viewed microscopically, the sarcomeres have a banding pattern of A bands (dark bands) with a ____________ at the centre.

    <p>M line</p> Signup and view all the answers

    The ______________ marks the boundary between adjacent sarcomeres and is attached to thin filaments.

    <p>Z line</p> Signup and view all the answers

    In the _________________ thin filaments are situated between the thick filaments and they can slide across each other during contraction.

    <p>Zone of Overlap</p> Signup and view all the answers

    Strands of the protein ___________, which stretch from one Z line to the next M line, function to keep the thick and thin filaments in proper alignment, helps resist extreme stretching, and returns stretched muscles to resting length.

    <p>titin</p> Signup and view all the answers

    A strand of the protein __________________ lies alongside thin filaments (and is attached to the M line), which helps align thin filaments of the sarcomere.

    <p>Nebulin</p> Signup and view all the answers

    Under resting conditions, interaction between thick and thin filaments and thus muscle fibre contraction is prevented by the ___________________ complex.

    <p>Troponin-tropomyosin</p> Signup and view all the answers

    Muscle fibre contraction involves the interaction of ______________ of the thick filaments with binding sites (active sites) on the thin filaments.

    <p>Myosin heads</p> Signup and view all the answers

    Which strands are part of the thin filament and function to cover active sites thus preventing actin-myosin interaction?

    <p>Tropomyosin</p> Signup and view all the answers

    How many subunits does a troponin molecule have?

    <p>3</p> Signup and view all the answers

    When a skeletal muscle contracts:

    <p>The width of the A band remains constant</p> Signup and view all the answers

    During contraction, thin filaments slide towards the centre of each sarcomere alongside the thick filaments and sliding occurs in every sarcomere along a myofibril, thus the:

    <p>Myofibril gets shorter</p> Signup and view all the answers

    The model representing the physical changes that occur, which describes what happens to the sarcomere during contraction is called the:

    <p>Sliding filament theory</p> Signup and view all the answers

    Normal skeletal muscle contraction only occurs when skeletal muscle fibres are activated by motor neurons resulting in so-called:

    <p>Excitation-contraction coupling</p> Signup and view all the answers

    The first step in muscle contraction is the release of _________ into the sarcoplasm.

    <p>calcium ions</p> Signup and view all the answers

    After release from the sarcoplasmic reticulum, ions then trigger interactions between ___________________________, resulting in muscle fibre contraction.

    <p>Thick and thin filaments</p> Signup and view all the answers

    Interactions during contraction produce __________________ and consume energy.

    <p>tension</p> Signup and view all the answers

    When sarcomeres shorten in a contraction, they _________________ the muscle fibre:

    <p>Shorten</p> Signup and view all the answers

    __________________ produced by an individual muscle fibre, or indeed an entire skeletal muscle, can vary widely and can change moment to moment.

    <p>tension</p> Signup and view all the answers

    A muscle fibre is either contracting ('on') or relaxed ('off'), this is the ______________________ and when a fibre contracts it does so fully (although it may not shorten fully).

    <p>All-or-none principle</p> Signup and view all the answers

    A single stimulus-contraction-relaxation sequence in a muscle fibre is called a twitch, which can be measured as a:

    <p>Myogram</p> Signup and view all the answers

    Which of the following can NOT be used to describe part of a single twitch:

    <p>Tetanic phase</p> Signup and view all the answers

    If a skeletal muscle is stimulated a second time immediately after the relaxation phase has ended, the force will rise; if this happens repeatedly force rises like steps in a staircase, a phenomenon called:

    <p>Treppe</p> Signup and view all the answers

    If a second stimulus arrives before the relaxation phase has ended a second, more powerful contraction occurs, which is referred to as:

    <p>Wave summation</p> Signup and view all the answers

    _____________________ is induced in muscle when the stimulation rate is increased so much that the relaxation phase is completely eliminated.

    <p>Complete tetanus</p> Signup and view all the answers

    Which of these is not one of the three major types of skeletal muscle fibre:

    <p>Resistant</p> Signup and view all the answers

    What is generally considered in terms of power and endurance?

    <p>Muscle performance</p> Signup and view all the answers

    Study Notes

    Muscle Tissue and Functions

    • Muscle tissue is highly specialized for contraction.
    • There are three types of muscle tissue: smooth, cardiac, and skeletal.
    • Skeletal muscle tissue forms skeletal muscles which contain connective tissues, nerves, and blood vessels.
    • Each skeletal muscle cell is a single muscle fibre.
    • Skeletal muscles perform numerous functions including maintenance of posture, guarding entrances and exits, movement of digestive contents, and support of soft tissues.

    Muscle Fibre Structure

    • Muscle fibres are formed by fusion of myoblasts during development.
    • The cell membrane of a muscle fibre is called the sarcolemma.
    • Electrical impulses are transmitted through transverse (T) tubules into muscle cells to trigger contraction.
    • Myofibrils are cylindrical structures responsible for muscle fibre contraction.
    • Myofibrils are composed of myofilaments, which are protein filaments made up of thin and thick filaments.
    • The sarcoplasmic reticulum (SR) is an intracellular membrane complex containing Ca2+ ions.
    • Calcium (Ca2+) ions are released into the sarcoplasm upon receiving electrical signals.

    Sarcomere: The Functional Unit of Muscle Contraction

    • Myofilaments are organized into repeating units called sarcomeres, responsible for generating muscle contraction.
    • A sarcomere contains thin filaments, thick filaments, proteins that regulate filament generation, and proteins that stabilize filament positions.
    • Sarcomeres exhibit a banding pattern when viewed microscopically, with A bands (dark) and an M line at the center.
    • The Z line marks the boundary between adjacent sarcomeres and is attached to thin filaments.
    • The zone of overlap is the region where thin filaments interdigitate with thick filaments and sliding occurs during contraction.

    Protein Structure and Function in Sarcomeres

    • Titin is a protein that connects the Z line to the M line, maintaining alignment, resisting stretching, and returning stretched muscles to resting length.
    • Nebulin aligns thin filaments within the sarcomere.
    • Under resting conditions, the troponin-tropomyosin complex prevents interaction between thick and thin filaments, inhibiting muscle fibre contraction.

    Muscle Contraction Mechanisms

    • Muscle fibre contraction involves the interaction of myosin heads with binding sites on thin filaments.
    • Tropomyosin strands cover active sites on thin filaments, preventing actin-myosin interaction.
    • Troponin is a protein with three subunits, and it plays a role in regulating the interaction of tropomyosin with myosin.
    • During contraction, thin filaments slide towards the center of each sarcomere, shortening the myofibril.
    • The sliding filament theory describes the physical changes that occur within the sarcomere during contraction.

    Excitation-Contraction Coupling and Muscle Twitch

    • Normal skeletal muscle contraction is initiated by activation from motor neurons, a process called excitation-contraction coupling.
    • The initial step in muscle contraction is the release of calcium (Ca2+) ions into the sarcoplasm.
    • These ions then trigger interactions between thick and thin filaments, leading to muscle fibre contraction.
    • Muscle fibre contractions involve the production of tension and consume ATP.
    • A single stimulus-contraction-relaxation sequence in a muscle fibre is called a twitch and can be measured using a myogram.
    • A single twitch can be divided into a latent period, contraction phase, and relaxation phase.

    Muscle Twitch Summation and Tetanus

    • If a skeletal muscle is stimulated repeatedly, the force of contraction increases, a phenomenon known as treppe.
    • When a second stimulus arrives before the relaxation phase has ended, a more powerful contraction occurs, known as wave summation or temporal summation.
    • Complete tetanus occurs when the stimulation rate is high enough to eliminate the relaxation phase, resulting in a sustained contraction.

    Skeletal Muscle Fibre Classification

    • There are three major types of skeletal muscle fibres: slow, fast, and intermediate, each with different characteristics regarding power and endurance.

    Muscle Performance

    • Muscle fibre classification and fatigue are important aspects related to muscle performance.

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    Description

    This quiz explores the specialized structures and functions of muscle tissue, including the three types: smooth, cardiac, and skeletal. Discover how muscle fibres are formed and how they function in contraction and overall muscle operations. Ideal for students studying human anatomy and physiology.

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