Muscle Physiology Quiz

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Questions and Answers

Which method is NOT a way in which a muscle fiber can acutely increase force output?

  • Decreasing firing rate of motor neurons (correct)
  • Recruiting more motor units
  • Preloading the muscle
  • Increasing speed of contraction

What is an example of an isometric muscle action?

  • Bicep curls
  • Lifting a weight
  • Doing a plank (correct)
  • Lowering a weight

As contraction speed increases, the force generated by a muscle fiber generally:

  • Increases
  • Becomes unpredictable
  • Decreases (correct)
  • Remains the same

Which type of contraction involves the muscle lengthening while producing force?

<p>Eccentric contraction (D)</p> Signup and view all the answers

When aiming to generate maximum force during concentric contractions, what speed should you focus on?

<p>Slow speeds (D)</p> Signup and view all the answers

Which term best defines contractions where muscle length changes and force is produced simultaneously?

<p>Dynamic (B)</p> Signup and view all the answers

What is true about the relationship between force generation and eccentric muscle actions?

<p>Force can be generated quickly without loss (D)</p> Signup and view all the answers

What defines isotonic contractions?

<p>Force remains constant while length changes (A)</p> Signup and view all the answers

What is the primary function of muscle spindles?

<p>To sense changes in muscle length and initiate the stretch reflex. (C)</p> Signup and view all the answers

How can more force be generated in a muscle without increasing the strength of the signal?

<p>By recruiting more motor units. (B)</p> Signup and view all the answers

What occurs during summation in muscle contractions?

<p>Increased frequency of stimuli prevents relaxation of muscle fibers. (C)</p> Signup and view all the answers

Where is isometric muscle action represented on the force velocity curve?

<p>At a velocity of zero. (C)</p> Signup and view all the answers

What role do Golgi tendon organs (GTOs) play in muscle contraction?

<p>They prevent excessive tension by signaling muscle relaxation. (D)</p> Signup and view all the answers

Power differs from force primarily because it includes which factor?

<p>The time component of the action. (A)</p> Signup and view all the answers

What sequence is involved in the neurophysiological model of the stretch reflex?

<p>Muscle spindle activation triggers signal to the spinal cord. (D)</p> Signup and view all the answers

What type of muscle contraction is considered the weakest?

<p>Concentric contraction. (A)</p> Signup and view all the answers

What is the role of the amortization phase in the stretch-shortening cycle (SSC)?

<p>To conduct a brief pause for optimal force production (C)</p> Signup and view all the answers

How does the Golgi tendon organ (GTO) activation benefit muscle stretching?

<p>Promotes muscle relaxation for better range of motion (B)</p> Signup and view all the answers

In what order does the General Adaptation Syndrome (GAS) process occur?

<p>Alarm, Resistance, Adaptation (B)</p> Signup and view all the answers

Which of the following best describes the eccentric phase of the SSC?

<p>Muscle lengthening under tension (B)</p> Signup and view all the answers

Which of the following is NOT a neural adaptation to strength training?

<p>Increased muscle fiber cross-sectional area (D)</p> Signup and view all the answers

Which type of training is primarily aimed at achieving hypertrophy?

<p>Performing 6 to 12 repetitions with 67-85% load (A)</p> Signup and view all the answers

What occurs during the concentric phase of the stretch-shortening cycle?

<p>Elastic energy from tendons is converted into kinetic energy (A)</p> Signup and view all the answers

Which of the following factors is NOT crucial for muscle adaptation in resistance training?

<p>Regular consumption of protein supplements (C)</p> Signup and view all the answers

What is the primary role of beta receptors in the bronchi?

<p>Relax bronchi to improve airflow (D)</p> Signup and view all the answers

Why do steroid hormones utilize intracellular receptors while peptide hormones do not?

<p>Steroid hormones can pass through cell membranes (D)</p> Signup and view all the answers

What pathway does epinephrine use to stimulate fat metabolism?

<p>Cyclic AMP pathway (C)</p> Signup and view all the answers

What is the main function of IGF-1 stimulated by growth hormone?

<p>Stimulate fat metabolism (A)</p> Signup and view all the answers

What differentiates the mechanism of action between steroid and peptide hormones?

<p>Peptide hormones bind to receptors on cell membranes (C)</p> Signup and view all the answers

During a graded exercise test (GXT), why do levels of epinephrine and norepinephrine increase?

<p>As a response to physical stress and activation of the sympathetic nervous system (B)</p> Signup and view all the answers

Which hormone is produced by the adrenal cortex that aids in protein metabolism?

<p>Cortisol (A)</p> Signup and view all the answers

What is the role of glucagon in glycogenolysis?

<p>Activates cyclic AMP pathway to initiate glycogen breakdown (B)</p> Signup and view all the answers

What is the effect of increasing the firing rate of motor neurons in muscle contraction?

<p>It can lead to a supramaximal force output. (B)</p> Signup and view all the answers

Which type of muscle fibers are primarily recruited for greater power outputs?

<p>Type 2b fibers (B)</p> Signup and view all the answers

What does hypertrophy refer to in muscle development?

<p>Increase in the size of muscle cells. (A)</p> Signup and view all the answers

Which adaptation occurs primarily in endurance athletes to improve VO2max?

<p>Increase in a-vo2 difference. (A)</p> Signup and view all the answers

During acute responses to exercise, what typically happens to heart rate (HR) and stroke volume (SV)?

<p>Both HR and SV increase. (B)</p> Signup and view all the answers

What is the role of RNA polymerase in transcription?

<p>It synthesizes mRNA from DNA. (B)</p> Signup and view all the answers

What is primarily responsible for the release of growth hormone (GH) from the pituitary gland?

<p>Growth releasing hormone from the hypothalamus. (D)</p> Signup and view all the answers

Which of the following statements about hyperplasia is correct?

<p>It refers to an increase in the number of muscle cells. (B)</p> Signup and view all the answers

What happens to blood glucose levels during exercise?

<p>They increase due to glycogen breakdown in the liver. (D)</p> Signup and view all the answers

What is a common chronic response to regular endurance training?

<p>Increased muscular density. (B)</p> Signup and view all the answers

What is the primary role of glucagon in the body?

<p>To promote the breakdown of glycogen to glucose (A)</p> Signup and view all the answers

Which hormone is primarily produced by adipose tissue and regulates body fat?

<p>Leptin (D)</p> Signup and view all the answers

Which of the following statements about the JAK/STAT pathway is true?

<p>STAT dimer regulates gene transcription after entering the nucleus. (C)</p> Signup and view all the answers

What adaptation occurs in response to aerobic training that contributes to improved cardiovascular efficiency?

<p>Enhanced capillary density (C)</p> Signup and view all the answers

How does activating the AMPK pathway during exercise benefit individuals with Type 2 diabetes?

<p>It enhances insulin sensitivity. (B)</p> Signup and view all the answers

What is the correct sequence of events in protein synthesis after a steroid hormone binds to its receptor?

<p>Steroid binds to receptor, initiates gene transcription, mRNA is translated. (A)</p> Signup and view all the answers

Which factor is NOT associated with an increased VO2max?

<p>Decreased capillary density (B)</p> Signup and view all the answers

Which of the following muscle adaptations occurs at rest after aerobic training?

<p>Lower excess post-exercise oxygen consumption (EPOC) (D)</p> Signup and view all the answers

Flashcards

Motor Unit Recruitment

The process of activating more motor units to increase muscle force. It's like adding more soldiers to your army to increase the strength of your force.

Summation Principle

Repeated activation of a muscle fiber before it can fully relax leads to an increase in tension, resulting in a stronger contraction and greater force output. It's like stacking up small pieces of muscle force to create a larger, more powerful force.

Motor Unit Type & Force

Type 1 motor units (slow twitch) are smaller and produce less force compared to Type 2 motor units (fast twitch) which are larger and generate more power. It's like comparing a small car to a large truck.

Preloading a Muscle

Activating the stretch reflex in a muscle by slightly stretching it before a contraction helps to increase force output. It's like pre-stretching a rubber band before launching it.

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Speed of Contraction & Force

As the speed of a muscle contraction increases, the force it generates generally decreases. It's like a car - the faster you drive, the less weight you can haul.

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Isometric Muscle Action

Muscle action that produces force without changing length. It's like pushing against a wall - you're using muscle force, but not moving.

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Dynamic Muscle Action

Muscle action that produces force with length changes. It's like lifting weights - you're using muscle force and changing the length of the muscle.

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Concentric & Eccentric Contractions

Concentric contractions shorten the muscle while producing force (lifting a weight), while eccentric contractions lengthen the muscle while producing force (lowering a weight). It's like pushing against a door opening or closing it.

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All-or-None Principle

A nerve or muscle fiber will either completely respond to a stimulus or not at all, regardless of its strength or duration.

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Summation

The addition of tension in a muscle during repeated stimulation, leading to a stronger contraction.

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Muscle Spindles

Sensory receptors located within muscles that detect changes in muscle length and initiate the stretch reflex.

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Golgi Tendon Organs (GTOs)

Sensory receptors located within tendons that detect changes in muscle tension and act as a protective mechanism against excessive force.

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Stretch Reflex

An involuntary muscle contraction in response to a rapid stretch, triggered by muscle spindles.

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Isometric Contraction

A muscle contraction where muscle length remains constant, generating force without movement.

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Eccentric Contraction

A muscle contraction where the muscle lengthens while generating force, often stronger than concentric contractions.

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VO2

The volume of oxygen consumed by the body during exercise. It reflects the rate at which your body is using oxygen.

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VO2max

The maximum amount of oxygen a person can utilize during strenuous physical activity. A higher VO2max indicates better aerobic fitness.

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a-vO2 difference

The difference in oxygen content between arterial blood (oxygenated blood) and venous blood (deoxygenated blood) during exercise. Reflects the amount of oxygen extracted by the working muscles.

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Mitochondrial Density

The number of mitochondria per unit of muscle tissue. Mitochondria are the powerhouses of the cells, responsible for energy production.

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Capillary Density

The number of capillaries per unit of muscle tissue. Capillaries are tiny blood vessels that deliver oxygen and nutrients to the muscles.

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Transcription

The process of converting genetic information encoded in DNA into messenger RNA (mRNA).

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Translation

The process of using mRNA to create a protein chain. This happens in the cytoplasm.

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Hypothalamus

A brain region that controls many physiological processes, including the release of growth hormone.

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Growth Hormone

A hormone that stimulates growth and muscle development.

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Catecholamines

A group of hormones that regulate various physiological processes, including the fight-or-flight response. They play a key role in the acute responses to exercise.

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Stretch-Shortening Cycle (SSC)

A sequence of movements involving an eccentric phase (muscle lengthening), an amortization phase (brief pause), and a concentric phase (muscle shortening) that utilizes elastic energy stored in tendons for powerful muscle contractions.

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Amortization Phase

The brief transition period between the eccentric and concentric phases of the SSC, where the muscle is briefly paused to allow for maximum energy transfer from the stretched tendons to the muscle.

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General Adaptation Syndrome (GAS)

A three-phase physiological response to stress, encompassing an alarm phase (initial stress), a resistance phase (adaptation), and an exhaustion phase (overtraining).

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Progressive Overload

The principle of gradually increasing the demands placed on the body during training to promote adaptation and improvement.

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Neural Adaptations

Changes in the nervous system that occur in response to resistance training, leading to increased muscle strength and power.

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Muscle Hypertrophy

The increase in size and volume of muscle fibers, primarily due to increased protein synthesis and enhanced myofibril density.

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Insulin's Role

Insulin lowers blood glucose levels by promoting glucose uptake by cells, glycogen synthesis in the liver and muscle, and inhibiting glucose production by the liver.

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Glucagon's Role

Glucagon raises blood glucose levels by stimulating glycogen breakdown in the liver, gluconeogenesis, and inhibiting glucose uptake by cells.

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AMPK Pathway in Type 2 Diabetes

Activating the AMPK pathway during exercise improves insulin sensitivity, increases glucose uptake by muscles, and promotes fat burning, which could help manage blood sugar levels in Type 2 diabetics.

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Steroid Hormone Action: Transcription

Steroid hormones, like testosterone, enter the cell and bind to a receptor, which then binds to DNA and initiates the transcription of mRNA.

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Steroid Hormone Action: Translation

The mRNA produced by transcription leaves the nucleus and is translated by ribosomes to create a protein.

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JAK/STAT Pathway: Step 1-2

Growth hormone binds to its receptor, activating JAK, which then phosphorylates STAT.

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JAK/STAT Pathway: Step 3-5

Two phosphorylated STAT molecules form a dimer, which enters the nucleus and activates gene transcription, resulting in the production of new proteins.

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Growth Hormone Release

Growth hormone (GH) is released from the pituitary gland. Factors stimulating GH release include exercise, sleep, and low blood glucose levels.

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Beta Receptor Stimulation

Activation of beta receptors in the body leads to various physiological responses, including bronchodilation (relaxation of airways) and increased sweat production in working muscles.

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Diurnal Hormone Variations

The fluctuations in hormone secretion levels throughout the day. These changes can be influenced by factors like sleep-wake cycles, meal times, and stress levels.

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Peptide Hormone Receptors

Located on the cell surface, these receptors bind to peptide hormones triggering a signal cascade that leads to intracellular changes.

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Steroid Hormone Receptors

Located inside the cell, these receptors bind to steroid hormones, influencing gene expression and protein synthesis.

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Second Messenger System

A chain reaction within a cell triggered by a signal from outside (like a peptide hormone). This system amplifies the initial signal and produces a specific cellular response.

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Epinephrine & Norepinephrine in Exercise

These stress hormones increase during exercise due to the activation of the sympathetic nervous system, preparing the body for 'fight or flight' by increasing heart rate.

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IGF-1 & GH Interaction

Growth hormone (GH) stimulates the release of IGF-1 (Insulin-like Growth Factor 1) which helps regulate GH's effects and promotes fat metabolism.

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Epinephrine's Role in Fat Metabolism

Epinephrine utilizes cyclic AMP (cAMP) as a second messenger to activate a pathway that breaks down fat stores for energy production.

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Study Notes

Muscle Fiber Force Output

  • Muscle fibers acutely increase force output through five ways:
    • Recruiting more motor units. This depends on the load.
    • Increasing the firing rate of motor neurons. Repeated activation without relaxation allows tension summation.
    • Recruiting specific motor unit types. Type 1 (slow-twitch) fibers are used for strength, while Type 2 (fast-twitch) fibers are used for power.
    • Activating the stretch reflex using preloading. The muscle is activated as it's stretched.
    • Increasing the speed of contraction.

Muscle Actions

  • Static (isometric): The muscle produces force, but its length doesn't change. Examples include planks and wall sits.
  • Dynamic: The muscle produces force, and its length changes.
    • Concentric: The muscle shortens while producing force. An example is lifting weights (reps).
    • Eccentric: The muscle lengthens while producing force. An example is lowering weights (reps).
  • Isotonic: The force stays the same during the movement. Examples often include bicep curls.
  • Isokinetic: The speed of the movement stays the same, meaning it can be concentric or eccentric. Examples include weight machines or hydro-exercise.

Force and Velocity Relationship

  • Force and velocity of contraction are inversely related. As velocity increases, force decreases (and vice versa). Faster contractions generate less force. This is primarily seen in concentric isotonic contractions (shortening/speed).

Muscle Spindles and GTOs

  • Muscle spindles are located within muscles. They sense changes in muscle length and trigger the stretch reflex to prevent excessive stretching and maintain stability.
  • Golgi tendon organs (GTOs) are located within the tendons. They detect tension in the tendon and trigger relaxation to prevent muscle damage during forceful contractions.

General Adaptation Syndrome (GAS)

  • This is a physiological response to stress, including resistance training.
  • The process includes alarm, resistance, and an adaptation or exhaustion period.
  • Proper recovery leads to adaptation, while improper recovery leads to exhaustion.

Neural Adaptations in Strength

  • Neural adaptations are important in early strength gains.
  • Greater recruitment of motor units and improved stimulation of motor units allow for increased force production. Proprioceptors also play a role.

Muscle Hypertrophy

  • Hypertrophy is an increase in muscle size.
  • Sarcoplasmic hypertrophy involves an increase in the amount of sarcoplasm (fluid portion of muscle cells).
  • Myofibrillar hypertrophy involves an increase in the size of the myofibrils, increasing the number of myofilaments (actin and myosin).

Bioenergetic Adaptations

  • Bioenergetics is a component of endurance training that enhances the processes of producing and delivering energy.

VO2 (Oxygen Consumption)

  • VO2 is the measurement of oxygen consumption.
  • VO2 max is the maximal amount of oxygen that can be consumed during exercise.

Hormonal Responses

  • During exercise, various hormones play critical roles and are regulated by the hypothalamus and the pituitary gland.
  • Hormones like GH, epinephrine, and norepinephrine play a part in acute responses to exercise.
  • Long-term adaptations can include changes in muscle's ability to produce energy and the cardiovascular system's capacity.

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