Podcast
Questions and Answers
Where is P-glycoprotein expressed?
Where is P-glycoprotein expressed?
- Muscle tissue
- Intestinal epithelium (correct)
- Bone marrow
- Skin cells
What is the function of P-glycoprotein in cancer cells?
What is the function of P-glycoprotein in cancer cells?
- Enhances drug absorption
- Inhibits drug metabolism
- Enhances excretion of drugs (correct)
- Promotes drug synthesis
Which cancer type is NOT mentioned as showing multi-drug resistance?
Which cancer type is NOT mentioned as showing multi-drug resistance?
- Ovarian cancer
- Prostate cancer
- Melanoma (correct)
- Lung cancer
What induces the expression of P-glycoprotein in some cancer cells?
What induces the expression of P-glycoprotein in some cancer cells?
Which molecule inhibits the efflux of some drugs by P-glycoprotein?
Which molecule inhibits the efflux of some drugs by P-glycoprotein?