Multi-Drug Resistance in Cancer Cells Quiz

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Questions and Answers

Where is P-glycoprotein expressed?

  • Muscle tissue
  • Intestinal epithelium (correct)
  • Bone marrow
  • Skin cells

What is the function of P-glycoprotein in cancer cells?

  • Enhances drug absorption
  • Inhibits drug metabolism
  • Enhances excretion of drugs (correct)
  • Promotes drug synthesis

Which cancer type is NOT mentioned as showing multi-drug resistance?

  • Ovarian cancer
  • Prostate cancer
  • Melanoma (correct)
  • Lung cancer

What induces the expression of P-glycoprotein in some cancer cells?

<p>Cisplatin (C)</p> Signup and view all the answers

Which molecule inhibits the efflux of some drugs by P-glycoprotein?

<p>Tamoxifen (D)</p> Signup and view all the answers

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