Mucosal Lesions in Patients

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Questions and Answers

What percentage of patients typically exhibit mucosal lesions?

Almost all (correct)

A small majority

More than half

A minority

Where may mucosal lesions first appear?

Eyes

Mouth (correct)

Skin

Ears

What role do mucosal lesions play in patient symptoms?

They are a late-stage symptom

They are never a presenting symptom

They are always asymptomatic

They are the only manifestation in some patients (correct)

What is the relationship between mucosal lesions and the underlying condition?

The lesions are a symptom of the condition Signup and view all the answers

What is the significance of mucosal lesions in patients?

They are a common and important symptom Signup and view all the answers

What is the result of applying firm sliding pressure with a finger?

Erosion of normal looking epidermis Signup and view all the answers

What is the layer of skin that separates from the demis?

Epidermis Signup and view all the answers

What is the name of the sign that is positive when firm sliding pressure is applied?

Nikolysky's sign Signup and view all the answers

What is the consequence of applying firm sliding pressure to the skin?

Erosion of the epidermis Signup and view all the answers

What is the underlying structure that the epidermis separates from?

Dermis Signup and view all the answers

What is the frequency of finding intact bullae in the mouth?

Rare Signup and view all the answers

What is typically observed in the mouth instead of intact bullae?

Erosions Signup and view all the answers

Where are the erosions typically located in the mouth?

Buccal or palatal Signup and view all the answers

What happens to the bullae as a result of the disease?

They rupture and lead to erosions Signup and view all the answers

What is characteristic of the erosions in the mouth?

They are slow to heal Signup and view all the answers

What can be a challenge for diagnosis and treatment of mouth lesions?

The rarity of intact bullae Signup and view all the answers

What is a possible complication of the disease?

Pigmentary changes Signup and view all the answers

What is the relationship between disease activity and morbidity/mortality?

Disease activity is directly proportional to morbidity and mortality Signup and view all the answers

What is the outcome of the erosions in terms of scarring?

They heal slowly with no scarring Signup and view all the answers

What is the severity of the disease in terms of morbidity and mortality?

The disease has a high morbidity and mortality rate Signup and view all the answers

What is a potential consequence of systemic steroid treatment?

Hypertension Signup and view all the answers

Why is careful monitoring essential for patients treated with systemic steroids?

To identify all complications of steroids Signup and view all the answers

What is a potential metabolic consequence of systemic steroid treatment?

Hyperglycemia Signup and view all the answers

What is the primary concern when treating patients with systemic steroids?

Identifying potential complications Signup and view all the answers

What should clinicians do when treating patients with systemic steroids?

Monitor for all potential complications Signup and view all the answers

Study Notes

Mucosal Lesions in Patients

Almost all patients exhibit mucosal lesions, which may be the presenting symptoms or the only manifestation of the disease.
In the mouth, intact bullae are rare, but erosions are common, particularly on the buccal or palatal surfaces.
These erosions are slow to heal and can be induced by firm sliding pressure with a finger, leading to separation of normal-looking epidermis from dermis, which is a positive Nikolysky's sign.
The bullae typically rupture, resulting in erosions that heal slowly with no scarring.

Complications of Treatment

Patients treated with systemic steroids are at risk of developing various complications, including hypertension and glucose intolerance.
Close monitoring of patients is necessary to mitigate these risks.

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Description

Mucosal lesions are common in patients and can be the presenting symptoms, especially in the mouth. They may be the only manifestation of an underlying condition.