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Questions and Answers
ما هو الكبد؟
ما هو الكبد؟
الكبد هو عضو كبير في البطن مسؤول عن العديد من الوظائف الحيوية.
أين يقع الكبد؟
أين يقع الكبد؟
يقع الكبد في الجزء العلوي الأيمن من البطن ، أسفل الحجاب الحاجز.
ما هي وظيفة الكبد؟
ما هي وظيفة الكبد؟
وظائف الكبد عديدة ، تتضمن تصفية الدم وتخزين العناصر الغذائية وإنتاج العصارة الصفراوية ، وتنظيم مستويات السكر في الدم.
ما هي أنواع الخلايا الرئيسية الموجودة في الكبد ؟
ما هي أنواع الخلايا الرئيسية الموجودة في الكبد ؟
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ما هي وظيفة خلايا الكبد؟
ما هي وظيفة خلايا الكبد؟
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ما هو الصفراء؟
ما هو الصفراء؟
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ما هو البيليروبين؟
ما هو البيليروبين؟
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البيليروبين غير المترافق هو شكل البيليروبين الذي يُفرز في البول.
البيليروبين غير المترافق هو شكل البيليروبين الذي يُفرز في البول.
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ما هي وظيفة إنزيم الجلوكورونيل ترانسفيراز؟
ما هي وظيفة إنزيم الجلوكورونيل ترانسفيراز؟
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ما هو اليرقان؟
ما هو اليرقان؟
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ما هي أنواع اليرقان؟
ما هي أنواع اليرقان؟
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ما هو اليرقان قبل الكبدي؟
ما هو اليرقان قبل الكبدي؟
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ما هو اليرقان الكبدي؟
ما هو اليرقان الكبدي؟
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ما هي أسباب التهاب الكبد؟
ما هي أسباب التهاب الكبد؟
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ما هي أسباب التليف الكبدي؟
ما هي أسباب التليف الكبدي؟
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التليف الكبدي هو مرض خطير يمكن أن يؤدي إلى فشل الكبد.
التليف الكبدي هو مرض خطير يمكن أن يؤدي إلى فشل الكبد.
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ما هي وظيفة الكبد في هضم الطعام؟
ما هي وظيفة الكبد في هضم الطعام؟
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ما هي وظيفة الكبد في تنظيم مستويات السكر في الدم؟
ما هي وظيفة الكبد في تنظيم مستويات السكر في الدم؟
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ما هي وظيفة الكبد في إزالة السموم؟
ما هي وظيفة الكبد في إزالة السموم؟
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ما هي وظيفة الكبد في تصنيع البروتينات؟
ما هي وظيفة الكبد في تصنيع البروتينات؟
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What is the primary reason for the conjugation of bilirubin?
What is the primary reason for the conjugation of bilirubin?
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Which component is most closely associated with hepatic jaundice?
Which component is most closely associated with hepatic jaundice?
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What is the role of Kupffer cells in the liver?
What is the role of Kupffer cells in the liver?
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Which of the following statements best differentiates pre-hepatic from post-hepatic jaundice?
Which of the following statements best differentiates pre-hepatic from post-hepatic jaundice?
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Which condition is primarily indicated by elevated levels of delta bilirubin?
Which condition is primarily indicated by elevated levels of delta bilirubin?
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How does the liver contribute to lipid metabolism?
How does the liver contribute to lipid metabolism?
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What is the primary consequence of chronic cirrhosis?
What is the primary consequence of chronic cirrhosis?
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Which enzyme is primarily responsible for the conjugation of bilirubin?
Which enzyme is primarily responsible for the conjugation of bilirubin?
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Study Notes
Liver Function Key Terms and Objectives
- Bile: A fluid produced by the liver, essential for digestion.
- Bilirubin: A yellow pigment resulting from the breakdown of red blood cells.
- Cirrhosis: A chronic liver disease marked by scarring.
- Conjugated bilirubin: Water-soluble form of bilirubin.
- Crigler-Najjar syndrome: Genetic disorder affecting bilirubin metabolism.
- Delta bilirubin: Bilirubin conjugated with glucuronic acid in the blood.
- Hepatic jaundice: Jaundice resulting from liver dysfunction,
- Hepatitis: Inflammation of the liver.
- Hepatocellular carcinoma: Cancer originating in the liver cells.
- Icterus: Yellowing of the skin and eyes due to high bilirubin levels.
- Jaundice: Yellowing of the skin and/or eyes.
- Kupffer cells: Specialized macrophages in the liver involved in immune function.
- Post-hepatic jaundice: Jaundice associated with problems after the liver, often biliary tract issues.
- Pre-hepatic jaundice: Jaundice linked to issues before the liver, often related to red blood cell breakdown.
- Unconjugated bilirubin: Water-insoluble form of bilirubin.
- Uridine diphosphate glucuronosyltransferase (UDPGT): Enzyme crucial for bilirubin conjugation.
- Urobilinogen: A metabolite of bilirubin excreted in the urine.
Liver Anatomy and Function
- Liver Location and Blood Supply: The liver's location and blood supply are crucial for its function.
- Liver Lobules: Lobules are the functional units of the liver.
- Blood Flow Through the Liver: Blood flows through the liver via the hepatic portal vein and hepatic artery.
- Liver Cell Types and Function: Two important cell types in the liver are hepatocytes and Kupffer cells.
- Four Major Functions of the Liver: The liver performs numerous functions; four major ones include carbohydrate metabolism, lipid metabolism, protein metabolism, and detoxification.
- Bilirubin Metabolism Steps: The steps involved in bilirubin metabolism are detailed and critical.
Bilirubin Conjugation and Jaundice
- Unconjugated vs. Conjugated Bilirubin: Explain the differences and importance of conjugation.
- Conjugation Mechanism: The process of bilirubin conjugation in the liver is described.
- Liver Function and Bile Secretion/Detoxification: The role of the liver and bile in the process of secretion and detoxification is highlighted.
- Pre-hepatic, Hepatic, and Post-hepatic Jaundice: The different types of jaundice and their causes are explored.
- Bilirubin Reference Ranges: Age-specific bilirubin reference ranges are considered.
- Total and Direct Bilirubin Measurements: The methods for measuring these are compared.
- Liver Role in Carbohydrate, Lipid, and Protein Metabolism: Detailed descriptions of the roles.
- Liver Role in Detoxification and Drug Metabolism: The significance of detoxification in the liver is expanded upon.
- Clinical Significance of Jaundice and Kernicterus: The significance of jaundice in patients is discussed.
- Causes and Treatment of Jaundice Types: The causes and treatment are explored in detail.
- Genetic disorders associated with Hepatic Jaundice: Genetic causes are examined.
- Light Therapy for Jaundice: The mechanism for how it works in treating jaundice is described.
- Liver Cancer: Information including metastasis, causes and treatments are included.
Liver Function Measurement and Disorders
- Diazo Reaction Principle: This is explained.
- Calculating Unconjugated Bilirubin: A method to calculate this is described if given.
- Bilirubin Fractions: Understanding the fractions of bilirubin in blood is explained.
- Specimen Requirements for Bilirubin Tests: The specifications and preservation processes are detailed.
- Light Protection during Bilirubin Testing: The processes and rationale for light protection during bilirubin tests is discussed.
- Urobilinogen Pathway: The pathway of urobilinogen is described.
- Hepatitis Causes: Common causes of hepatitis are listed.
- Enzyme Markers for Liver Disease: Common enzymes and how they are used to differentiate liver issues.
- Liver Disorders and Diagnosis: Liver disorders and methods for diagnosing them are explicitly presented.
- Laboratory Data Correlations: Correlations with normal or pathological liver findings are explained.
- Comparing Total and Direct Bilirubin Measurements: Comparison of methods for measuring bilirubin, and their use in diagnosis.
- Hepatitis Types: Detailed information about various hepatitis types (causes, transmission, occurrence, alternate names, physiology, diagnosis, and treatment).
- Applying Liver Function Knowledge to Case Studies: How to apply the knowledge gained to case studies in the chapter.
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Description
هذا الاختبار يختبر معرفتك بمصطلحات وأهداف وظائف الكبد. يُغطي مواضيع مثل الصفرة، التهاب الكبد، وأهمية الصفراء في عملية الهضم. استعد لتوسيع فهمك حول صحة الكبد وأمراضه.