Moyamoya Disease: Brain CT Angiography
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Questions and Answers

Which of the following symptoms is NOT associated with Ischemic symptoms of Moyamoya disease?

  • Transient ischemic attacks (TIAs) or stroke
  • Sudden severe headache (correct)
  • Weakness or numbness in the face, arm, or leg
  • Seizures
  • What is the primary cause of Moyamoya disease?

  • Environmental factors only
  • Both genetic and environmental factors (correct)
  • Unknown
  • Genetic factors only
  • What does CT Angiography (CTA) enable in the diagnosis of Moyamoya disease?

  • Detection of neurofibromatosis type 1
  • Visualization of cerebral ischemia or infarction
  • Identification of atherosclerosis
  • Diagnosis of Moyamoya disease by visualizing stenosis or occlusion of the internal carotid artery and its branches (correct)
  • What is a characteristic imaging feature of Moyamoya disease?

    <p>Moyamoya vessels (abnormal net-like vessels) at the base of the brain</p> Signup and view all the answers

    What is a differential diagnosis of Moyamoya disease?

    <p>Atherosclerosis</p> Signup and view all the answers

    What is a hemorrhagic symptom of Moyamoya disease?

    <p>Sudden severe headache</p> Signup and view all the answers

    What is the primary effect of the blockage of the carotid artery in Moyamoya disease?

    <p>Decrease in oxygen delivery to the front two-thirds of the brain</p> Signup and view all the answers

    What is the characteristic of the new blood vessels formed in Moyamoya disease?

    <p>They are weaker and smaller than the blocked artery</p> Signup and view all the answers

    What is the result of the brain's attempt to compensate for the blockage in Moyamoya disease?

    <p>Increased risk of brain bleeds and strokes</p> Signup and view all the answers

    Which arteries are typically affected in Moyamoya disease?

    <p>The carotid and middle cerebral arteries</p> Signup and view all the answers

    What is the primary goal of treatment in Moyamoya disease?

    <p>To manage symptoms and prevent blood clots</p> Signup and view all the answers

    What is the effect of the blockage of the front and/or middle cerebral arteries in Moyamoya disease?

    <p>Reduced blood flow to the front two-thirds of the brain</p> Signup and view all the answers

    What does the term 'moyamoya' refer to in the context of Moyamoya disease?

    <p>A characteristic shape of smaller backup vessels</p> Signup and view all the answers

    Why is Moyamoya disease more common in people assigned female at birth?

    <p>For reasons that scientists don't understand</p> Signup and view all the answers

    What is the primary age range when Moyamoya disease occurs more often?

    <p>Around 5 to 10 years old and between 30 and 50 years old</p> Signup and view all the answers

    What is the first sign of Moyamoya disease in many patients?

    <p>Stroke or repeated transient ischemic attacks (TIAs)</p> Signup and view all the answers

    What is the purpose of bypass surgery in Moyamoya disease?

    <p>To redirect blood flow around the blocked vessels</p> Signup and view all the answers

    Why is it important to control vascular risk factors in Moyamoya disease?

    <p>To reduce the risk of moyamoya syndrome</p> Signup and view all the answers

    Study Notes

    Brain CT Angiography in Moyamoya Disease

    Cause

    • Moyamoya disease is a rare, progressive cerebrovascular disorder caused by bilateral stenosis or occlusion of the internal carotid artery and its branches.
    • The exact etiology is unknown, but it is thought to be related to genetic and environmental factors.
    • Moyamoya disease can be primary (idiopathic) or secondary to various conditions, such as atherosclerosis, radiation, or neurofibromatosis type 1.

    Symptoms

    • Ischemic symptoms:
      • Transient ischemic attacks (TIAs) or stroke
      • Weakness or numbness in the face, arm, or leg
      • Confusion or memory loss
      • Seizures
    • Hemorrhagic symptoms:
      • Sudden severe headache
      • Nausea and vomiting
      • Altered mental status
      • Seizures

    Imaging

    • CT Angiography (CTA)
      • Non-invasive imaging modality that provides detailed vascular anatomy
      • Enables diagnosis of Moyamoya disease by visualizing stenosis or occlusion of the internal carotid artery and its branches
      • Can identify collateral circulation, including moyamoya vessels
    • Imaging Features
      • Bilateral stenosis or occlusion of the internal carotid artery and its branches
      • Moyamoya vessels (abnormal net-like vessels) at the base of the brain
      • Collateral circulation, including enlarged middle cerebral arteries and posterior cerebral arteries
      • Cerebral ischemia or infarction may be present
    • Differential Diagnosis
      • Atherosclerosis
      • Vasculitis
      • Central nervous system vasculitis
      • Reversible cerebral vasoconstriction syndrome

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    Description

    This quiz covers the causes, symptoms, and imaging features of Moyamoya disease, a rare cerebrovascular disorder characterized by bilateral stenosis or occlusion of the internal carotid artery and its branches. Learn about the diagnostic role of CT Angiography in identifying stenosis, occlusion, and collateral circulation. Test your knowledge of this complex condition.

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