Podcast
Questions and Answers
What is a primary role of mouthwash in a patient's oral care regime?
What is a primary role of mouthwash in a patient's oral care regime?
Which active ingredient is described as an oxygenating agent in mouthwash?
Which active ingredient is described as an oxygenating agent in mouthwash?
In what scenario may a mouthwash be recommended?
In what scenario may a mouthwash be recommended?
What is one of the constituents commonly found in mouthwash that acts mainly as a preservative?
What is one of the constituents commonly found in mouthwash that acts mainly as a preservative?
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Which of the following is NOT a benefit of using mouthwash?
Which of the following is NOT a benefit of using mouthwash?
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What influence may affect a consumer's choice in mouthwash?
What influence may affect a consumer's choice in mouthwash?
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Which component of mouthwash is often perceived to provide freshness and improve taste?
Which component of mouthwash is often perceived to provide freshness and improve taste?
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What should clinicians consider when recommending a mouthwash?
What should clinicians consider when recommending a mouthwash?
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What is one of the functions of astringents mentioned in the content?
What is one of the functions of astringents mentioned in the content?
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Which of the following is an example of an anodyne?
Which of the following is an example of an anodyne?
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What do buffering agents aim to reduce?
What do buffering agents aim to reduce?
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Which agent is known for neutralizing odours from decomposing food?
Which agent is known for neutralizing odours from decomposing food?
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What benefit does fluoride provide in mouthwashes?
What benefit does fluoride provide in mouthwashes?
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What is the role of chlorobutanol in ELUDRIL?
What is the role of chlorobutanol in ELUDRIL?
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Which category does chlorhexidine belong to?
Which category does chlorhexidine belong to?
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Which of the following does NOT represent a type of antimicrobial mentioned?
Which of the following does NOT represent a type of antimicrobial mentioned?
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What condition might fluoride be beneficial for?
What condition might fluoride be beneficial for?
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What is a potential drawback of using deodorizing agents mentioned in the content?
What is a potential drawback of using deodorizing agents mentioned in the content?
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What is the maximum alcohol content found in some mouthwashes?
What is the maximum alcohol content found in some mouthwashes?
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What potential risk is associated with swallowing mouthwash that contains alcohol?
What potential risk is associated with swallowing mouthwash that contains alcohol?
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What effect can alcohol in mouthwash have on restorative dental materials?
What effect can alcohol in mouthwash have on restorative dental materials?
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Which of the following is NOT a potential concern with alcohol-containing mouthwashes?
Which of the following is NOT a potential concern with alcohol-containing mouthwashes?
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Why should caution be taken with mouthwashes containing alcohol?
Why should caution be taken with mouthwashes containing alcohol?
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What is the reliability of the evidence linking alcohol in mouthwash to oral malignancies?
What is the reliability of the evidence linking alcohol in mouthwash to oral malignancies?
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In certain individuals, what may result from the alcohol content in mouthwash?
In certain individuals, what may result from the alcohol content in mouthwash?
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What is a primary benefit of Chlorhexidine in dental care?
What is a primary benefit of Chlorhexidine in dental care?
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What concentration of Chlorhexidine is considered bactericidal?
What concentration of Chlorhexidine is considered bactericidal?
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What is an important characteristic of Chlorhexidine's action in the mouth?
What is an important characteristic of Chlorhexidine's action in the mouth?
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Which of the following is a common potential side effect of Chlorhexidine?
Which of the following is a common potential side effect of Chlorhexidine?
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In which dental condition is Chlorhexidine particularly indicated for use?
In which dental condition is Chlorhexidine particularly indicated for use?
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What is the recommended duration of use for Chlorhexidine to avoid side effects?
What is the recommended duration of use for Chlorhexidine to avoid side effects?
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What effect does Chlorhexidine have at low concentrations?
What effect does Chlorhexidine have at low concentrations?
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What effect can Chlorhexidine have on taste perception?
What effect can Chlorhexidine have on taste perception?
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Which of the following is NOT an ingredient mentioned in relation to oral care?
Which of the following is NOT an ingredient mentioned in relation to oral care?
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What unique effect does Chlorhexidine have on bacterial cells?
What unique effect does Chlorhexidine have on bacterial cells?
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What is the primary active ingredient in Corsodyl original mouthwash?
What is the primary active ingredient in Corsodyl original mouthwash?
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Which of the following compounds has been noted to have poor oral retention?
Which of the following compounds has been noted to have poor oral retention?
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What natural antibacterial ingredient is found in essential oils?
What natural antibacterial ingredient is found in essential oils?
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What is the historical use of Triclosan?
What is the historical use of Triclosan?
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Which of the following compounds has greater initial oral retention than Chlorhexidine?
Which of the following compounds has greater initial oral retention than Chlorhexidine?
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What is a benefit of using Oxygenating agents like Hydrogen peroxide?
What is a benefit of using Oxygenating agents like Hydrogen peroxide?
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What effect does Chlorhexidine have on plaque reduction?
What effect does Chlorhexidine have on plaque reduction?
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Which ingredient is primarily associated with anti-inflammatory effects?
Which ingredient is primarily associated with anti-inflammatory effects?
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What is the main characteristic of Hexetidine found in Oraldene?
What is the main characteristic of Hexetidine found in Oraldene?
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Which natural compound is known for effective anti-plaque properties?
Which natural compound is known for effective anti-plaque properties?
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Study Notes
Mouthwashes
- Mouthwashes are chemotherapeutic agents used as an adjunct to patient's home care oral regime.
- The aim is to gain insight into the range and potential role of mouthwashes in oral health.
Learning Outcomes
- Understand the various constituents found in mouthwashes.
- Appreciate the potential benefits of constituents on oral health.
- Understand the potential disadvantages of certain constituents on oral health.
- Analyze information to advise patients accordingly.
- GDC learning outcomes include 1.1.1, 1.1.8, 1.2.3, 1.9.1, 1.10.2, 1.10.3, 1.10.4, 1.10.5, 6.1, 6.2, 6.3.
What is a Mouthwash?
- A mouthwash or mouth rinse is a chemotherapeutic agent used as an adjunct to a patient's home care system in their oral care regime.
- Mouthwashes should not be used as a replacement for mechanical plaque removal.
When May a Mouthwash be Recommended?
- When good oral hygiene/toothbrushing is difficult (e.g., medically, physically, or mentally compromised).
- When there are oral ulcers or conditions (e.g., lichen planus, aphthous ulcers).
- After oral surgery.
- For xerostomia sufferers.
- For caries control (fluoride component).
- Cosmetic use: fresh taste and fresh breath.
General Constituents of a Mouthwash
- Water
- Alcohol (preservative)
- Flavoring
- Coloring
- Sweeteners
- Active ingredients
Actions of Active Ingredients
- Antimicrobial
- Physical removal of plaque
- Crystalline impact
- Deodorizing
- Buffering agents
- Astringent
- Anodynes
Oxygenating Agents
- Cleansing effervescent and introduction of O2.
- Examples include Sodium Perborate, Hydrogen Peroxide.
- Some antibacterial effect on anaerobic bacteria, but not broad spectrum.
Astringents
- Tissue shrinkage.
- Examples include Zinc Chloride, Zinc Acetate, Citric acid.
Anodynes
- Help to alleviate pain.
- Examples include Phenol derivatives, Essential oils.
Buffering Agents
- Reduce acidity and reduce soreness.
- Examples include Sodium Perborate, Sodium Bicarbonate.
Deodorizing Agents
- Neutralize odors from decomposing food.
- Example: Chlorine Dioxide.
Fluoride
- Improves caries prevention and management of demineralization.
- Works in patients with xerostomia and dental sensitivity.
- Some mouthwashes have a higher fluoride percentage.
Pain Relief
- Some mouthwashes, such as Eludril, contain an antimicrobial (e.g., chlorhexidine) and a mild local anesthetic (e.g., chlorobutanol).
Antimicrobials
- Bisbiguanides (e.g., chlorhexidine)
- Bispyridines (e.g., ocetedine)
- Pyrimidines (e.g., hexetidine)
- Halogens (e.g., fluoride, iodine)
- Phenols (e.g., phenol, thymol)
- Quaternary Ammonium Compounds (e.g., cetylpyridinium chloride)
- Herbal (e.g., sanguinarine)
- Oxidizing agents
- Fluoride
General Considerations
- Active ingredient
- Justification for recommendation
- Duration of use
- Side effects
- Cost
- Patient access
Chlorhexidine
- Broad-spectrum antimicrobial.
- Effectively combats periodontal disease-related bacteria.
- Absorbed onto all oral surfaces.
- Has good substantivity (slowly released and stays active for up to 24 hours).
- Bactericidal (high concentration) causes cell lysis, incorporates into bacteria, impacts cell membrane leading to lysis, and extreme potassium & phosphate leakage
- Bacteriostatic (low concentration) causes cell content leakage of potassium & phosphates, reduces replication, but can recover.
- Indications for use: gingivitis, periodontal disease, gingival conditions, compromised oral hygiene, oral ulcers, or oral conditions.
Potential Side Effects
- Staining
- Taste disturbance
- Tongue discomfort & burning
- Oral desquamation
- Swelling of the Parotid
- Can affect certain constituents in toothpastes (rare side effects)
Corsodyl Mouthwash Range
- Daily range contains chlorhexidine 0.06%.
- Original Corsodyl contains chlorhexidine gluconate 0.2%.
Phenolic Compounds
- Less effective than chlorhexidine.
- Poor oral retention.
- Has some anti-inflammatory effects.
- Reduces plaque by up to 30%.
- Works by altering the bacterial cell wall.
- Works in association with essential oils.
- Common examples: Listerine.
Essential Oils
- Natural antibacterials (e.g., menthol).
- Natural anti-inflammatory agents (e.g., eucalyptus).
- Natural antiseptics (e.g., thymol).
- Often incorporated into phenolic compounds.
Triclosan
- Derivative of phenol.
- Used in toothpastes and some mouthwashes.
- Broad-spectrum antibacterial and some anti-inflammatory effects.
- Originally used as a hospital scrub in the 1970s.
- Now found in various products, including toothpastes, mouthwashes, soaps, and shampoos.
- Safety/toxicity concerns are emerging.
Cetylpyridinium Chloride
- Moderate plaque inhibitory effect.
- Has greater initial oral retention and equivalent antibacterial activity to chlorhexidine, but less effective in inhibiting plaque and preventing gingivitis.
- Dentyl is an oil-and-water-based product.
Hexetidine
- Antimicrobial found in mouthwash, such as Oraldene.
Sanguinarine
- Plant-based mouthwash.
- Effective anti-plaque properties.
Oxygenating Agents (Hydrogen Peroxide)
- Beneficial in certain conditions (e.g., AUG), as it inhibits anaerobic bacteria.
Mouthwashes and Alcohol Content
- Many mouthwashes contain alcohol, up to 26%.
- Caution is needed if accidentally swallowed.
- Some studies link alcohol in mouthwashes to oral malignancies, but evidence is not strong.
- Alcohol can cause soft tissue discomfort in some individuals, and may affect restorative materials.
References
- A range of relevant academic articles and webpages are suggested for further reading (see the recommended reading section of the presentation).
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Description
This quiz explores the role of mouthwashes as chemotherapeutic agents in oral care. It covers the constituents of mouthwashes, their benefits and disadvantages, and when they may be recommended. Gain a deeper understanding of how mouthwashes can be incorporated into a patient’s oral hygiene routine.