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Questions and Answers
What is the purpose of an intraperitoneal glucose tolerance test (IPGTT) in mice?
What is the purpose of an intraperitoneal glucose tolerance test (IPGTT) in mice?
- To assess insulin levels in response to glucose administration
- To measure the clearance of an intraperitoneally injected glucose load from the body (correct)
- To determine the fasting blood glucose levels before glucose injection
- To evaluate the impact of medication on glucose homeostasis
What is one of the key requirements for animals undergoing IPGTT?
What is one of the key requirements for animals undergoing IPGTT?
- Exercising for at least 30 minutes daily
- Being hydrated with water for 24 hours
- Consuming a high-fat diet for 2 weeks
- Fasting for approximately 16 hours (correct)
Which factor may vary in different GTT variations?
Which factor may vary in different GTT variations?
- The ambient temperature during the test
- Blood-sampling intervals (correct)
- The color of the solution injected
- The type of anesthesia used
What does IPGTT primarily assess in mice?
What does IPGTT primarily assess in mice?
What is the duration for which blood glucose level is measured during IPGTT?
What is the duration for which blood glucose level is measured during IPGTT?
In addition to blood glucose concentrations, what else may be assessed during GTT variations?
In addition to blood glucose concentrations, what else may be assessed during GTT variations?