ANA/HIST-C BREASTS

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33 Questions

What is responsible for activating the secretion of milk in lactating mammary glands?

Prolactin

Which type of cells are partially surrounded by a meshwork of myoepithelial cells in the acini?

Epithelial glandular cells

What is the protein-rich fluid that engorges the breasts in preparation for newborns?

Colostrum

Which organelle is abundant in the secretory cells of lactating mammary glands?

Rough endoplasmic reticulum

What type of cells are indicated by the arrows in the higher magnification of an active mammary gland?

Plasma cells

What type of cells become cuboidal with nuclei positioned at the basal cell surface in the third trimester?

Epithelial glandular cells

What stimulates the proliferation of lactiferous duct components during the proliferative phase?

Estrogen

Which type of epithelium lines the lactiferous ducts?

Stratified squamous (keratinized) epithelium

Which cells are nonfunctional in the mammary gland?

Myoepithelial cells

During which phase do women perceive tenderness and a progressive increase of breast tissue mass?

Luteal phase

What characterizes the first trimester of development during pregnancy in relation to mammary glands?

Branching of the terminal ductules

Which cells infiltrate the intralobular connective tissue stroma during pregnancy?

Plasma cells

Which pathway involves exocytosis of milk protein and lactose in Golgi-derived secretory vesicles?

Pathway II

What is the main function of plasma cells?

Production of Immunoglobulin A dimers

Which cell process involves the secretion of ions and water across the apical membrane?

Exocytosis of milk protein and lactose

What type of pathway involves the paracellular transport of plasma components and leukocytes?

Pathway V

In what organelle are milk protein and lactose exocytosed before secretion?

Secretory vesicle

Which process involves pinocytosis and exocytosis of immunoglobulins?

Exocytosis of milk protein and lactose

Plasma cells are abundant in the lactating mammary glands.

False

The myoepithelial cells partially surround the cuboidal acinar cells in the mammary glands.

True

The terminal duct-lobular unit looks different during lactation compared to non-pregnancy.

True

Hypertrophy of secretory cells contributes to breast enlargement during pregnancy.

True

The main function of plasma cells in lactating mammary glands is to secrete milk proteins.

False

Oxytocin triggers the contraction of myoepithelial cells surrounding alveoli.

True

Colostrum is secreted from mammary glands on the 4th day after birth.

False

Milk composition includes 2% lipids.

False

Lactogenesis stage II occurs as progesterone levels rise after delivery of the placenta.

False

Water makes up 87% of milk composition.

True

Lactogenesis stage III marks an indefinite period of milk production known as galactopoiesis.

True

Lactose constitutes 7% of milk composition.

True

Immunoglobulin A provides temporary passive defense before infants develop their secretory IgA.

True

During lactogenesis, prolactin and human placental lactogen are essential hormones for alveolar development.

True

The milk ejection reflex involves the expression of milk from alveoli to ducts.

True

Test your knowledge on the morphologic changes in mammary glands during the menstrual cycle, including the effects of estrogen and progesterone, lactiferous duct components, and clinical manifestations like breast tenderness and tissue mass increase.

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