Mood Disorders in Psychiatry

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Questions and Answers

What are the two main categories that the DSM-5 separates mood disorders into?

  • Obsessive-compulsive and depressive disorders
  • Anxiety and depression disorders
  • Schizophrenia and bipolar disorders
  • Bipolar and depressive disorders (correct)

Which disorder is defined by one or more episodes of depression, each continuing for at least 2 weeks?

  • Major depressive disorder (correct)
  • Cyclothymic disorder
  • Premenstrual dysphoric disorder
  • Bipolar I disorder

What is the defining feature of bipolar II disorder?

  • Episodes of major depression
  • Episodes of hypomania lasting at least 4 days (correct)
  • Episodes of mania lasting at least 1 week
  • Marked affective lability associated with menses

In addition to elated or depressed mood, what other problems are common in patients with mood disorders?

<p>Physical symptoms and self-destructive behavior (A)</p> Signup and view all the answers

What duration of time characterizes an episode of mania in bipolar I disorder?

<p>At least 1 week (D)</p> Signup and view all the answers

What term describes marked affective lability associated with menses?

<p>Premenstrual dysphoric disorder (B)</p> Signup and view all the answers

Which disorder is characterized by hypomania and dysthymia occurring over a 2-year period (1 year in children) with no discrete episodes of illness?

<p>Cyclothymic disorder (C)</p> Signup and view all the answers

Which neurotransmitters are primarily associated with mood disorders?

<p>Norepinephrine and serotonin (B)</p> Signup and view all the answers

What is the lifetime prevalence of persistent depressive disorder (dysthymia) in women?

<p>Up to three times more common (D)</p> Signup and view all the answers

Which factor is NOT listed among the top five risk factors for suicide?

<p>Alcohol dependence (D)</p> Signup and view all the answers

What enzyme is reported to be moderately reduced in manic-depressive patients?

<p>Monoamine oxidase (MAO) (B)</p> Signup and view all the answers

What is the concordance rate of monozygotic twins in relation to genetic factors of mood disorders?

<p>About 75% (B)</p> Signup and view all the answers

Which disorder is characterized by depression continuing over a 2-year period (1 year in children) with no discrete episodes of illness?

<p>Persistent depressive disorder (D)</p> Signup and view all the answers

Which neurotransmitter's activity may be decreased during depressive episodes and increased during manic episodes?

<p>Dopamine (B)</p> Signup and view all the answers

What are the top five risk factors for suicide listed, from higher to lower risk?

<p>Serious prior suicide attempt, Age older than 45 years, Alcohol dependence, History of rage and violent behavior, Male sex (C)</p> Signup and view all the answers

What are the top five risk factors for suicide listed, from lower to higher risk?

<p>None of the above (D)</p> Signup and view all the answers

Flashcards

Mood Disorder Categories

The DSM-5 divides mood disorders into two main categories: Bipolar and Depressive Disorders. Bipolar disorders involve periods of mania or hypomania, while depressive disorders are characterized by periods of low mood and energy.

Major Depressive Disorder

Defined by one or more episodes of depression, each lasting at least 2 weeks. These episodes are marked by symptoms like depressed mood, loss of interest, and fatigue.

Bipolar II Disorder

Characterized by episodes of hypomania lasting at least 4 days, along with episodes of major depression.

Common Symptoms of Mood Disorders

Beyond mood changes, physical symptoms (like fatigue and sleep disturbances) and self-destructive behaviors are also common in patients with mood disorders.

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Mania in Bipolar I Disorder

An episode of mania in Bipolar I disorder lasts at least 1 week, with symptoms like elevated mood, inflated self-esteem, and racing thoughts.

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Premenstrual Dysphoric Disorder

Marked affective lability (mood swings) associated with menses. It's a more severe form of premenstrual syndrome.

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Cyclothymic Disorder

Characterized by hypomania and dysthymia (mild depression) occurring over a 2-year period (1 year in children). There are no distinct episodes of illness.

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Neurotransmitters in Mood Disorders

Norepinephrine and serotonin are the key neurotransmitters associated with mood disorders. Their levels are often imbalanced in patients.

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Persistent Depressive Disorder (Dysthymia)

Depression continuing over a 2-year period (1 year in children), with no clear-cut episodes. Symptoms are milder but chronic.

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Dopamine in Mood Disorders

Dopamine activity may be decreased during depressive episodes and increased during manic episodes. It plays a role in motivation and pleasure.

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Lifetime Prevalence of Dysthymia

Up to three times more common in women compared to men.

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Top 5 Risk Factors for Suicide (Highest to Lowest)

  1. Serious prior suicide attempt, 2. Age over 45, 3. Alcohol dependence, 4. History of rage and violent behavior, 5. Male sex.
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Monoamine Oxidase (MAO) in Mood Disorders

Reported to be moderately reduced in patients with manic-depressive disorder. MAO is an enzyme that breaks down neurotransmitters.

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Genetic Factors in Mood Disorders

Concordance rate of monozygotic (identical) twins is about 75%. This suggests a strong genetic influence.

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Top 5 Risk Factors for Suicide (Lowest to Highest)

None of the above. The risk factors were already listed in order from highest to lowest risk.

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