Molecular Mechanisms of Skeletal Muscle Contraction Quiz

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Questions and Answers

What is the primary function of creatine phosphate in the formation of ATP in muscle fibers?

  • To act as a storage form of high-energy phosphate bonds (correct)
  • To serve as a cofactor for the enzyme creatine kinase
  • To provide a rapid source of phosphate for the glycolytic pathway
  • To catalyze the oxidative phosphorylation of ADP in the mitochondria

Which of the following statements about the role of creatine phosphate in ATP formation is correct?

  • Creatine phosphate is the primary source of ATP for muscle contraction. (correct)
  • Creatine phosphate is formed through the oxidative phosphorylation of ADP in the mitochondria.
  • The concentration of creatine phosphate increases at the start of muscle contraction.
  • The breakdown of creatine phosphate is an irreversible reaction.

How does the concentration of ATP and ADP change in a muscle fiber at the start of contraction?

  • Both ATP and ADP concentrations remain constant.
  • ATP concentration increases while ADP concentration also increases.
  • ATP concentration increases while ADP concentration decreases.
  • ATP concentration decreases while ADP concentration increases. (correct)

What is the primary limitation of the creatine phosphate system in providing ATP for muscle contraction?

<p>The concentration of creatine phosphate in the cell is limited. (C)</p> Signup and view all the answers

Which of the following best describes the reversible reaction catalyzed by creatine kinase?

<p>Creatine phosphate + ADP → Creatine + ATP (A)</p> Signup and view all the answers

What is the primary advantage of the creatine phosphate system in providing ATP for muscle contraction?

<p>It can generate ATP more rapidly than glycolysis or oxidative phosphorylation. (B)</p> Signup and view all the answers

What is the function of the H zone in skeletal muscle?

<p>It is a space between the opposing ends of two sets of thin filaments in each sarcomere. (B)</p> Signup and view all the answers

What does the M line in skeletal muscle correspond to?

<p>Proteins that link together the central region of adjacent thick filaments. (D)</p> Signup and view all the answers

What is the relationship between contraction and muscle fiber shortening?

<p>Contraction refers to activation of force-generating sites, but does not necessarily mean shortening. (D)</p> Signup and view all the answers

Which type of neurons innervate skeletal muscle fibers?

<p>Alpha motor neurons (C)</p> Signup and view all the answers

What is the advantage of myelinated axons in motor neurons?

<p>They allow faster propagation of action potentials. (D)</p> Signup and view all the answers

What is a motor unit?

<p>A single motor neuron and all the muscle fibers it innervates. (A)</p> Signup and view all the answers

What determines the maximal rate of cross-bridge cycling in skeletal muscle fibers?

<p>The type of myosin subtype present in the fiber (D)</p> Signup and view all the answers

Which type of skeletal muscle fibers have myosin with low ATPase activity?

<p>Slow-twitch fibers (A)</p> Signup and view all the answers

What are the two main subtypes of fast myosin distinguished based on structure?

<p>Type 2A and Type 2X (B)</p> Signup and view all the answers

Which type of myosin has about four times higher ATPase activity than the other?

<p>Type 2X myosin (A)</p> Signup and view all the answers

How are skeletal muscle fibers classified based on their major pathway to form ATP?

<p>Based on oxidative or glycolytic pathway usage (B)</p> Signup and view all the answers

What contributes to extra oxygen requirement in muscles after contraction has stopped?

<p>Accumulation of lactate (B)</p> Signup and view all the answers

Which type of muscle fibers contain numerous mitochondria and have high oxidative capacity?

<p>Slow-oxidative fibers (B)</p> Signup and view all the answers

What is responsible for the dark red color of oxidative muscle fibers?

<p>High myoglobin content (C)</p> Signup and view all the answers

Which type of muscle fibers have few mitochondria but a high concentration of glycolytic enzymes?

<p>Fast-glycolytic fibers (A)</p> Signup and view all the answers

What gives glycolytic muscle fibers their pale color?

<p>Lack of myoglobin (B)</p> Signup and view all the answers

Which characteristic distinguishes slow-oxidative muscle fibers?

<p>High myosin-ATPase activity and high oxidative capacity (A)</p> Signup and view all the answers

Which type of muscle fibers are often referred to as white muscle fibers?

<p>Fast-glycolytic fibers (D)</p> Signup and view all the answers

What type of muscle fibers combine high myosin-ATPase activity with high oxidative capacity and intermediate glycolytic capacity?

<p>Fast-oxidative-glycolytic fibers (type 2A) (C)</p> Signup and view all the answers

Which type of muscle fibers are resistant to fatigue and can maintain contractile activity for long periods with little tension loss?

<p>Slow-oxidative fibers (A)</p> Signup and view all the answers

Which type of skeletal muscle fibers are used for quick bursts of strong activation, like jumping or sprinting?

<p>Fast-glycolytic fibers (type 2X) (A)</p> Signup and view all the answers

In whole-muscle contraction, what is true about the muscle fibers within a single motor unit?

<p>They are all of the same fiber type. (C)</p> Signup and view all the answers

Which statement accurately describes the composition of most skeletal muscles?

<p>They consist of all three motor unit types interspersed with each other. (B)</p> Signup and view all the answers

What distinguishes fast-glycolytic skeletal muscles in terms of fatigue resistance?

<p>They fatigue rapidly. (C)</p> Signup and view all the answers

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