Podcast
Questions and Answers
What happens to properly folded proteins in the ER?
What happens to properly folded proteins in the ER?
- They stay in the ER indefinitely.
- They leave the ER to take different routes in biosynthetic-secretory pathways. (correct)
- They are transported back to the cytoplasm.
- They are degraded in the ER.
Which process involves the retrograde transport of proteins from the Golgi apparatus back to the ER?
Which process involves the retrograde transport of proteins from the Golgi apparatus back to the ER?
- Endocytosis
- Exocytosis
- Anterograde transport
- Retrograde transport (correct)
In vesicular traffic, what is the function of different coats?
In vesicular traffic, what is the function of different coats?
- Prevent vesicle formation
- Aid in protein synthesis
- Regulate vesicle transport between different compartments (correct)
- Only provide structural support to vesicles
In a polarised cell, what process involves the internalization of extracellular substances through invagination of the cell membrane?
In a polarised cell, what process involves the internalization of extracellular substances through invagination of the cell membrane?
Which organelle is involved in post-translational modification and packaging of proteins before they move via Golgi?
Which organelle is involved in post-translational modification and packaging of proteins before they move via Golgi?
What is the main mechanism cells use to package and transport proteins for export?
What is the main mechanism cells use to package and transport proteins for export?
What is the primary function of the endoplasmic reticulum mentioned in the text?
What is the primary function of the endoplasmic reticulum mentioned in the text?
How are signal sequences typically positioned in proteins targeted to the endoplasmic reticulum?
How are signal sequences typically positioned in proteins targeted to the endoplasmic reticulum?
Which process involves the removal of signal sequences by signal peptidases?
Which process involves the removal of signal sequences by signal peptidases?
In cotranslational translocation to the ER, where does the polypeptide chain pass through?
In cotranslational translocation to the ER, where does the polypeptide chain pass through?
How are membrane proteins typically inserted into the ER membranes?
How are membrane proteins typically inserted into the ER membranes?
Which cellular process involves the use of different coats for vesicular traffic?
Which cellular process involves the use of different coats for vesicular traffic?
What is the main mechanism by which proteins are sent for degradation if they fail to fold in the ER?
What is the main mechanism by which proteins are sent for degradation if they fail to fold in the ER?
How does the ER determine if a protein is ready to leave after folding?
How does the ER determine if a protein is ready to leave after folding?
In the context of ER protein folding and quality control, what role do chaperones play?
In the context of ER protein folding and quality control, what role do chaperones play?
Which process occurs during protein post-translational modification in the ER?
Which process occurs during protein post-translational modification in the ER?
What is the fate of misfolded proteins in the ER that cannot be properly refolded?
What is the fate of misfolded proteins in the ER that cannot be properly refolded?
