Molecular Biology: Gene Expression and Mutations
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Questions and Answers

What is the direction in which the RNA chain grows during transcription?

  • 3' to 5' direction
  • the direction of the template strand
  • the direction of the coding strand
  • 5' to 3' direction (correct)

    • Which of the following modifications occurs to all eukaryotic mRNA?

  • addition of a poly(G) tail to the 5' end of the molecule
  • addition of a poly(A) tail to the 3' end of the molecule (correct)
  • methylation of the 2' hydroxyl on the last nucleotide of the molecule
  • hydrolysis of the terminal phosphate from the 5' triphosphate end of the molecule

    • Can transcription and translation occur together in eukaryotic cells?

  • Depends on the type of cell
  • True
  • Sometimes
  • False (correct)

    • What is the direction in which RNA polymerase travels along the template strand during transcription?

    <p>3' to 5' direction</p> Signup and view all the answers

    What is the first step in gene transcription?

    <p>RNA polymerase is recruited to the promoter by general transcription factors</p> Signup and view all the answers

    What is the component labeled as A in the RNA molecule?

    <p>Phosphate group</p> Signup and view all the answers

    What is the percentage of adenine in the DNA of a particular animal species if it is 15% thymine?

    <p>35%</p> Signup and view all the answers

    During eukaryotic translation, how is the initiation codon found?

    <p>The first AUG codon is found when the 40S subunit scans the mRNA from the 5´ end</p> Signup and view all the answers

    What is the primary factor in determining how quickly an mRNA is degraded?

    <p>Length of poly(A) tail</p> Signup and view all the answers

    What is the consequence of alternative splicing?

    <p>Production of more than one viable protein product</p> Signup and view all the answers

    What is a prerequisite for reading the genetic code?

    <p>DNA strands are degraded</p> Signup and view all the answers

    What is the sequence of the template DNA strand if the RNA strand has the sequence GAGC?

    <p>CTCG</p> Signup and view all the answers

    What is the result of a mutation in the coding region of a gene?

    <p>An impact on the resulting polypeptide product</p> Signup and view all the answers

    What is true about the coding sequences of most eukaryotic genes?

    <p>They are interspersed with regions that are not expressed</p> Signup and view all the answers

    What is the purpose of the poly(A) tail on eukaryotic mRNA?

    <p>Binds to the poly(A) binding protein to prevent exonuclease activity</p> Signup and view all the answers

    What is the relationship between transcription and translation?

    <p>Transcription and translation are connected processes</p> Signup and view all the answers

    What is a characteristic of the association between amino acids and codons?

    <p>One amino acid is associated with multiple codons</p> Signup and view all the answers

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