Molecular Biology: Gene Expression and Mutations
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Questions and Answers

What is the direction in which the RNA chain grows during transcription?

  • 3' to 5' direction
  • the direction of the template strand
  • the direction of the coding strand
  • 5' to 3' direction (correct)

Which of the following modifications occurs to all eukaryotic mRNA?

  • addition of a poly(G) tail to the 5' end of the molecule
  • addition of a poly(A) tail to the 3' end of the molecule (correct)
  • methylation of the 2' hydroxyl on the last nucleotide of the molecule
  • hydrolysis of the terminal phosphate from the 5' triphosphate end of the molecule

Can transcription and translation occur together in eukaryotic cells?

  • Depends on the type of cell
  • True
  • Sometimes
  • False (correct)

What is the direction in which RNA polymerase travels along the template strand during transcription?

<p>3' to 5' direction (C)</p> Signup and view all the answers

What is the first step in gene transcription?

<p>RNA polymerase is recruited to the promoter by general transcription factors (D)</p> Signup and view all the answers

What is the component labeled as A in the RNA molecule?

<p>Phosphate group (B)</p> Signup and view all the answers

What is the percentage of adenine in the DNA of a particular animal species if it is 15% thymine?

<p>35% (B)</p> Signup and view all the answers

During eukaryotic translation, how is the initiation codon found?

<p>The first AUG codon is found when the 40S subunit scans the mRNA from the 5´ end (C)</p> Signup and view all the answers

What is the primary factor in determining how quickly an mRNA is degraded?

<p>Length of poly(A) tail (D)</p> Signup and view all the answers

What is the consequence of alternative splicing?

<p>Production of more than one viable protein product (A)</p> Signup and view all the answers

What is a prerequisite for reading the genetic code?

<p>DNA strands are degraded (B)</p> Signup and view all the answers

What is the sequence of the template DNA strand if the RNA strand has the sequence GAGC?

<p>CTCG (D)</p> Signup and view all the answers

What is the result of a mutation in the coding region of a gene?

<p>An impact on the resulting polypeptide product (B)</p> Signup and view all the answers

What is true about the coding sequences of most eukaryotic genes?

<p>They are interspersed with regions that are not expressed (D)</p> Signup and view all the answers

What is the purpose of the poly(A) tail on eukaryotic mRNA?

<p>Binds to the poly(A) binding protein to prevent exonuclease activity (D)</p> Signup and view all the answers

What is the relationship between transcription and translation?

<p>Transcription and translation are connected processes (D)</p> Signup and view all the answers

What is a characteristic of the association between amino acids and codons?

<p>One amino acid is associated with multiple codons (C)</p> Signup and view all the answers

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