Modern Cell Theory and History
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Questions and Answers

What did Robert Hooke observe when he looked at a thin slice of cork?

  • Hollow room-like structures (correct)
  • Animal cells only
  • Microscopic fungi
  • Living bacteria

Which scientist first observed living cells and referred to them as 'animalcules'?

  • Anton van Leeuwenhoek (correct)
  • Robert Hooke
  • Matthias Schleiden
  • Rudolph Virchow

What principle did Rudolph Virchow establish regarding living cells?

  • Only plant cells are made of cells
  • All living cells come from other living cells (correct)
  • Cells can spontaneously generate from non-living matter
  • All cells are identical in structure and function

What incorrect theory was disproven by Lazzaro Spallanzani's experiments?

<p>Life derives from spontaneous generation (A)</p> Signup and view all the answers

What did the early-nineteenth-century biological thought focus on regarding life's origin?

<p>Identifying the minimal unit carrying the potential for life (B)</p> Signup and view all the answers

What significant advancement allowed for the definitive proof of the neuron theory?

<p>The introduction of the electron microscope (B)</p> Signup and view all the answers

Which philosopher is known for his experimental approach and animal dissections?

<p>Aristotle (D)</p> Signup and view all the answers

Who is credited with the invention of the microscope?

<p>Galileo (D)</p> Signup and view all the answers

What was the influential concept proposed by Anaximander regarding evolution?

<p>Sea creatures transitioned to land creatures (A)</p> Signup and view all the answers

Which statement aligns with Aristotle's views on reproduction?

<p>A germ originates from a specific parent and yields a predictable progeny (D)</p> Signup and view all the answers

Which concept is attributed to Democritus, linking biology and atomic theory?

<p>Nothing can be created from nothing (D)</p> Signup and view all the answers

Which role did Plato play in the development of biological thinking?

<p>He provided philosophical frameworks for classification (D)</p> Signup and view all the answers

How do non-living things 'grow'?

<p>By accretion of materials externally (B)</p> Signup and view all the answers

Which of the following is true about the movement of non-living things?

<p>They cannot move by themselves. (D)</p> Signup and view all the answers

What is the significance of protoplasm in living things?

<p>It forms the basis for life to exist. (C)</p> Signup and view all the answers

How do non-living things respond to changes in their environment?

<p>They demonstrate physical changes based on influence. (C)</p> Signup and view all the answers

What defines the immortality of non-living things?

<p>They can last indefinitely. (D)</p> Signup and view all the answers

Which statement accurately reflects non-living things compared to living things?

<p>Non-living things have no requirements like water or air. (D)</p> Signup and view all the answers

In terms of cell structure, how do non-living things differ from living things?

<p>Non-living things do not have cells. (B)</p> Signup and view all the answers

What characterizes the M Phase of the cell cycle?

<p>The number of chromosomes remains unchanged. (D)</p> Signup and view all the answers

During which phase of mitosis does chromosomal material begin to condense?

<p>Prophase (D)</p> Signup and view all the answers

What happens to the nuclear envelope during prophase?

<p>It disappears completely. (D)</p> Signup and view all the answers

In which phase do chromosomes align at the metaphase plate?

<p>Metaphase (B)</p> Signup and view all the answers

What structure helps spindle fibers attach to chromosomes during metaphase?

<p>Kinetochores (A)</p> Signup and view all the answers

What happens to chromatids during anaphase?

<p>They begin to move towards opposite poles of the cell. (D)</p> Signup and view all the answers

What occurs during telophase?

<p>Chromosomes decondense and the nuclear membrane reforms. (C)</p> Signup and view all the answers

What is the main function of cytokinesis in the cell cycle?

<p>Division of the cytoplasm into two daughter cells. (A)</p> Signup and view all the answers

What characteristic is NOT true about anaphase?

<p>Chromosomes become visible after separation. (B)</p> Signup and view all the answers

Flashcards

Robert Hooke

English scientist who observed tiny, hollow, room-like structures in cork under a microscope, calling them 'cells' due to their resemblance to monks' rooms.

Anton van Leeuwenhoek

Dutch scientist who used a simple microscope to observe living cells in blood, rainwater, and teeth scrapings, some of which were later called bacteria.

Matthias Schleiden

German botanist known for his discovery that plant parts are composed of cells.

Theodor Schwann

German zoologist who extended Schleiden's findings by showing that animal parts are also made of cells.

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Rudolph Virchow

German physician who proposed that all living cells originate from existing cells.

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Who was Anaximander and what was his contribution to biology?

Anaximander was a Greek philosopher who lived in the 6th century B.C. He is credited with proposing early ideas about evolution, suggesting that life originated in the sea and transitioned to land.

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How did Plato impact biological studies?

Plato, a philosopher, did not directly contribute to biological discoveries. His focus was philosophical instead of experimental. However, many of his students went on to make significant contributions to the field of classification.

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Who was Democritus and what was his main contribution to biology?

Democritus, a prominent Atomist philosopher, believed that everything is made up of tiny, indivisible particles called atoms. This concept, known as atomic theory, has a strong connection to biology. One of his core beliefs was that nothing can be created from nothing.

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Why is Aristotle considered important for biological studies?

Aristotle, a Greek philosopher known for his experimental approach, dissected animals to study their structure and classify them. He sought to understand the connection between the body and the soul. Many of his animal classifications are still used today. He also predicted Mendelian genetics by suggesting that offspring inherit traits from their parents.

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What was the impact of the invention of the microscope on biology?

The invention of the microscope revolutionized biology by providing a tool to study the cellular world, which was previously invisible to the naked eye. This technology opened doors to understand the fundamental building blocks of life.

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Who is credited with inventing the microscope?

Galileo Galilei, a prominent scientist with diverse contributions, is credited with the invention of the microscope.

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What is the neuron theory and how was it proven?

The neuron theory states that the nervous system is composed of individual cells called neurons. This theory was definitively proven with the advent of the electron microscope, which allowed scientists to observe the intricate structure of neurons and their connections called synapses.

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M phase

The phase of the cell cycle where the cell divides its nucleus and cytoplasm, resulting in two daughter cells.

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Prophase

This is the first stage of mitosis, where the chromosomes begin to condense and become visible as sister chromatids attached by the centromere. The nuclear envelope, golgi, ER, and nucleolus start to disappear.

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Metaphase

During this stage, the condensed chromosomes align at the center of the cell, forming a plane called the metaphase plate. This alignment is driven by the attachment of spindle fibers to the kinetochores on the centromeres of the chromosomes.

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Anaphase

Sister chromatids, attached by the centromeres, separate and move towards opposite poles of the cell, pulled by the shortening spindle fibers.

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Telophase

The final stage of nuclear division, where the chromosomes reach opposite poles and decondense. The nuclear envelope, nucleolus, golgi, and ER reform around each set of chromosomes.

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Cytokinesis

The division of the cytoplasm into two daughter cells. In animal cells, this is achieved through a furrow in the plasma membrane that gradually deepens and joins the center, separating the cytoplasm.

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Kinetochores

These are the spindle fibers attached to the centromeres of the chromosomes during mitosis. They pull the sister chromatids apart during anaphase.

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Centromere

The structure that holds together the two sister chromatids during mitosis. It is also the point of attachment for the spindle fibers during cell division.

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Centrioles

A structure that helps organize the microtubules during mitosis. These structures migrate towards the poles of the cell, helping to create the spindle fibers.

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Non-living things lack life.

A defining characteristic of non-living things is that they don't possess life. They don't exhibit any signs of life, such as growth, reproduction, or movement.

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Absence of cells in non-living things

Unlike living organisms, non-living things do not consist of cells. They lack the fundamental building blocks of life - cells.

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No protoplasm in non-living things

Because non-living things lack cells, they also lack protoplasm, the living substance found inside cells. This means they are incapable of carrying out metabolic activities.

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Variable Shape in Non-living things

Non-living things do not have a fixed size. They can take on the shape of their container or environment. For example, a liquid takes the shape of its container, and rocks can be molded by erosion.

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External influence on non-living things

The change in the state or form of a non-living thing is caused by an external influence. For example, a snowball melts due to heat.

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Growth in non-living things

Non-living things grow by adding material externally. For example, a snowball gets bigger when more snow sticks to it.

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Immortality of non-living things

Non-living things do not have a lifespan and therefore cannot die. They do not have cells with a finite life cycle.

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Non-living things cannot reproduce.

Non-living things do not reproduce. They lack the ability to create new individuals of the same type.

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Absence of life processes in non-living things

Non-living things do not exhibit any life processes, such as nutrition, excretion, or respiration. They do not require food, air, or water to survive.

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Study Notes

  • Robert Hooke first discovered and named the cell in 1665, observing dead cell walls in cork.
  • Hooke's observations were documented in Micrographia.
  • Anton van Leeuwenhoek, in 1674, was the first to observe a live cell, the alga spirogyra, under a microscope.
  • The invention of the telescope made the Cosmos accessible to observation.
  • The invention of the microscope revealed the identities of microbes and allowed the observation of living forms.

Cell Theory

  • In 1838, Theodor Schwann and Matthias Schleiden formulated early conclusions about cells.
  • Cells are the fundamental units of structure, physiology, and organization in living organisms.
  • Cells retain independence as distinct entities while contributing to the structure of organisms.
  • Cells form through the division of pre-existing cells, according to Rudolf Virchow.

Modern Cell Theory

  • All living organisms are composed of cells.
  • Cells arise from pre-existing cells.
  • Cells contain hereditary information passed during division.
  • Cells exhibit a basic similarity in composition.
  • Energy flow and biochemical processes in life occur within cells.

Timeline of Cell Research

  • 1595 - Janssen credited with first compound microscope.
  • 1655 - Hooke described "cells" in cork.
  • 1674 - Leeuwenhoek discovered protozoa and bacteria.
  • 1833 - Brown described cell nuclei.
  • 1838 - Schleiden and Schwann proposed the cell theory.
  • 1856 - Pringsheim observed sperm entering egg.
  • 1858 - Virchow's famous conclusion: "Omnis cellula e cellula".
  • 1951 - Gey and coworkers established the HeLa cell line.
  • Various dates for subsequent scientific advancements in cell biology(including dates involving microscopy, gene expression, and manipulation tools for cells)

The Cell

  • The cell is the basic structural and functional unit of all living organisms.
  • Cells are comprised of both membrane bound and non membrane bound organelles.
  •  Cells have various organelles and structures performing designated functions to maintain homeostasis in the cell.

Cell Organelles

  • Nucleus: The control center, containing DNA.
  • Mitochondria: Powerhouses of the cell, responsible for energy production.
  • Endoplasmic Reticulum (ER): Network of membranes involved in protein and lipid synthesis.
  • Golgi apparatus: Modifies, sorts, and packages proteins and lipids.
  • Ribosomes: Site of protein synthesis.
  • Vacuoles: Storage sacs.
  • Chloroplasts: Site of photosynthesis in plant cells.
  • Cytoskeleton: Provides structure and support.
  • Cell membrane: Selectively permeable barrier surrounding the cell.
  •   Centrosome and Centrioles: Involved in cell division.

Cell Cycle

  • A cyclical series of events leading to cell growth and division.
  • Includes Interphase (G1, S, G2) and Mphase (mitosis).
  • Mitosis is further divided into Prophase, Metaphase, Anaphase, and Telophase and Cytokinesis

Evolution

  • The theory of natural selection explains how species evolve over time.
  • Species keep evolving or changing over time due to environmental changes.
  • Adaptations are required by species due to environment pressure.

Heredity

  • Genetics is the study of heredity and its related biological processes.
  • Gregor Mendel established principles of inheritance.
  • Mendel showed how characteristics are passed on in living organisms.

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Description

Explore the fascinating history and core principles of cell biology. From Robert Hooke's initial discoveries to the formulation of modern cell theory, this quiz delves into the significant milestones in understanding cellular structures and functions. Test your knowledge on how these ideas have evolved over time.

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