Questions and Answers
What is the trade name of Modafinil?
What therapeutic class does Modafinil belong to?
Central nervous system stimulants
What are the indications for using Modafinil?
To improve wakefulness in patients with excessive daytime drowsiness due to narcolepsy, obstructive sleep apnea, or shift work sleep disorder.
What is the mechanism of action (MOA) of Modafinil?
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What therapeutic effects does Modafinil provide?
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List some contraindications for Modafinil.
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In which conditions should Modafinil be used cautiously?
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What are some of the common adverse reactions/side effects of Modafinil?
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Name two drug interactions associated with Modafinil.
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What food substance should be considered when taking Modafinil?
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What nursing implications should be monitored while a patient is on Modafinil?
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What lab tests might show abnormalities in patients taking Modafinil?
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Study Notes
Modafinil Overview
- Trade name: Provigil
- Classified as a central nervous system stimulant.
Indications
- Used to enhance wakefulness in individuals with:
- Excessive daytime drowsiness from narcolepsy.
- Obstructive sleep apnea.
- Shift work sleep disorder.
Mechanism of Action
- Functions by producing CNS stimulation.
Therapeutic Effects
- Significantly reduces daytime drowsiness for:
- Patients suffering from narcolepsy.
- Individuals with obstructive sleep apnea.
- Workers experiencing drowsiness due to shift work disorder.
Contraindications
- Not suitable for individuals with:
- Hypersensitivity reactions.
- A history of left ventricular hypertrophy or ischemic ECG changes.
- Chest pain, arrhythmia, or related cardiovascular issues.
Cautionary Use
- Use cautiously in patients with:
- A history of myocardial infarction (MI) or unstable angina.
- Severe hepatic impairment.
- Current use of Monoamine Oxidase Inhibitors (MAOIs).
Adverse Reactions/Side Effects
- Common side effects include:
- Headache.
- Rhinitis (nasal inflammation).
- Increased liver enzymes.
- Nausea.
- Potential for suicidal ideation.
Drug Interactions
- May interact with:
- Antidepressants.
- Contraceptives.
Drug-Food Interactions
- Caffeine may affect the drug's efficacy or side effects.
Nursing Implications
- Important nursing actions include:
- Observing and documenting the frequency of narcoleptic episodes.
- Monitoring for signs of suicidal behavior.
- Watching for rash, angioedema, and potential anaphylaxis.
Laboratory Tests
- Can lead to elevated liver enzymes in patients.
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Test your knowledge on Modafinil with these flashcards. The quiz covers trade names, therapeutic classifications, indications, mechanisms of action, and effects. It's an excellent resource for students and professionals in the medical field.
