Podcast
Questions and Answers
What is the primary connection of the basal dendrites of mitral cells?
What is the primary connection of the basal dendrites of mitral cells?
- Granule cells (correct)
- Tufted cells
- Olfactory sensory neurons
- Periglomerular cells
According to some theories, what role do granule cells play in the olfactory bulb?
According to some theories, what role do granule cells play in the olfactory bulb?
- Directly activating mitral cells to transmit odor signals
- Providing excitatory input to tufted cells
- Relaying signals from olfactory sensory neurons to mitral cells
- Producing lateral inhibition between mitral cells (correct)
What is a potential function of lateral inhibition in the olfactory bulb?
What is a potential function of lateral inhibition in the olfactory bulb?
- Regulating the growth of new olfactory sensory neurons
- Enhancing the sensitivity of mitral cells to all odors
- Suppressing all neural activity in the olfactory bulb
- Boosting the signal-to-noise ratio of odor signals (correct)
How might lateral inhibition contribute to a clearer perception of a specific odor?
How might lateral inhibition contribute to a clearer perception of a specific odor?
If lateral inhibition were impaired, what might be a consequence for odor perception?
If lateral inhibition were impaired, what might be a consequence for odor perception?
What is the most likely effect of granule cells silencing the basal firing rate of surrounding non-activated neurons?
What is the most likely effect of granule cells silencing the basal firing rate of surrounding non-activated neurons?
Which of the following best describes the current understanding of the functional role of lateral inhibition in the olfactory bulb?
Which of the following best describes the current understanding of the functional role of lateral inhibition in the olfactory bulb?
How do granule cells contribute to the refinement of olfactory signals?
How do granule cells contribute to the refinement of olfactory signals?
Which neural circuit element is responsible for dampening the activity of neighboring mitral cells, thus sharpening odor discrimination?
Which neural circuit element is responsible for dampening the activity of neighboring mitral cells, thus sharpening odor discrimination?
What would be the outcome if the connection between mitral cells and granule cells was enhanced?
What would be the outcome if the connection between mitral cells and granule cells was enhanced?
What is the likely effect of increased granule cell activity on neighboring mitral cells that are weakly activated by a different odor?
What is the likely effect of increased granule cell activity on neighboring mitral cells that are weakly activated by a different odor?
If a specific odor activates a subset of mitral cells, what role might granule cells play in shaping the overall olfactory bulb response?
If a specific odor activates a subset of mitral cells, what role might granule cells play in shaping the overall olfactory bulb response?
How does lateral inhibition, potentially mediated by granule cells, affect the representation of multiple odors presented simultaneously?
How does lateral inhibition, potentially mediated by granule cells, affect the representation of multiple odors presented simultaneously?
What is the predicted outcome of a reduction in granule cell function within the olfactory bulb?
What is the predicted outcome of a reduction in granule cell function within the olfactory bulb?
What might be the consequence if the connections between mitral cells and granule cells were selectively weakened?
What might be the consequence if the connections between mitral cells and granule cells were selectively weakened?
How would the disruption of lateral inhibition in the olfactory bulb impact the ability to detect a weak odor in the presence of a strong background odor?
How would the disruption of lateral inhibition in the olfactory bulb impact the ability to detect a weak odor in the presence of a strong background odor?
What distinguishes the role of granule cells from that of mitral cells in olfactory processing?
What distinguishes the role of granule cells from that of mitral cells in olfactory processing?
What is one proposed mechanism by which granule cells may enhance the signal-to-noise ratio of odor signals?
What is one proposed mechanism by which granule cells may enhance the signal-to-noise ratio of odor signals?
If the inhibitory function of granule cells were selectively enhanced, what would be the most likely effect on odor perception?
If the inhibitory function of granule cells were selectively enhanced, what would be the most likely effect on odor perception?
How does lateral inhibition specifically influence the activity of mitral cells that are processing different components of a complex odor mixture?
How does lateral inhibition specifically influence the activity of mitral cells that are processing different components of a complex odor mixture?
Flashcards
Granule Cells
Granule Cells
Interneurons connected to the basal dendrites of mitral cells, thought to produce lateral inhibition.
Lateral Inhibition
Lateral Inhibition
A process where activated neurons suppress the activity of their neighbors.
Signal-to-Noise Ratio
Signal-to-Noise Ratio
Enhancing the strength of desired signals relative to background noise.
Basal Firing Rate
Basal Firing Rate
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Lateral Inhibition Function
Lateral Inhibition Function
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Effect of Lateral Inhibition
Effect of Lateral Inhibition
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Granule Cells Location
Granule Cells Location
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Study Notes
- Mitral cell basal dendrites connect to granule cells, which are interneurons
- Some theories propose that granule cells cause lateral inhibition between mitral cells
- The functional role of lateral inhibition is unclear
- Lateral inhibition might increase the signal-to-noise ratio of odor signals
- This could happen by silencing the basal firing rate of non-activated neurons nearby
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