Questions and Answers
What is the class of mitoxantrone?
What is the mechanism of action (MOA) of mitoxantrone?
Suppresses production of immune cells (B-cells, T-cells, macrophages)
How is mitoxantrone administered?
IV infusion every 3 months
How is mitoxantrone metabolized?
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Which of the following are adverse effects associated with mitoxantrone? (Select all that apply)
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Study Notes
Mitoxantrone Overview
- Classified as an immunosuppressant, targeting the immune system to manage various conditions.
Mechanism of Action
- Suppresses the production of immune cells including B-cells, T-cells, and macrophages, reducing immune response.
Administration Protocol
- Administered via IV infusion, typically every three months for sustained effect.
Metabolism Insights
- Metabolized slowly by the liver, requiring monitoring for toxicity especially in patients with liver failure.
Adverse Effects
- Bone marrow suppression leading to increased risk of infection, necessitating precautions.
- Potential for cardiotoxicity, impacting heart function.
- Likely teratogenic effects due to its action on rapidly dividing cells, posing risks during pregnancy.
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Description
This quiz provides an overview of mitoxantrone, an immunosuppressant used to manage various medical conditions. It covers its mechanism of action, administration protocols, metabolism, and potential adverse effects. Understanding these aspects is crucial for safe and effective patient care.
