Mitochondrial Disorders
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Questions and Answers

Which organelle is the only location of extra-chromosomal DNA within the cell?

  • Mitochondria (correct)
  • Nucleus
  • Endoplasmic reticulum
  • Golgi apparatus

What is the size of the human mitochondrial DNA (mtDNA) in base pairs?

  • 16,569 bp (correct)
  • 10,000 bp
  • 20,000 bp
  • 30,000 bp

How many mtDNA molecules are present in each human cell?

  • Hundreds (correct)
  • Millions
  • Thousands
  • Tens

What is the role of human mtDNA in protein synthesis?

<p>Encodes 13 of the 89 subunits of the mitochondrial respiratory chain (C)</p> Signup and view all the answers

How is mitochondrial genetics different from Mendelian genetics?

<p>Uniparental inheritance of disease mutations (B)</p> Signup and view all the answers

How many copies of mtDNA are present in each mitochondrion?

<p>Two to 10 (D)</p> Signup and view all the answers

How is mtDNA inherited?

<p>Maternally (C)</p> Signup and view all the answers

What is heteroplasmy?

<p>A mixture of mutant and normal mtDNAs (B)</p> Signup and view all the answers

Do mtDNA recombine?

<p>No (C)</p> Signup and view all the answers

What is replicative segregation in relation to mtDNA?

<p>The process of giving pure genotypes of mtDNA during division (D)</p> Signup and view all the answers

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