Mitochondrial Disorders

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10 Questions

Which organelle is the only location of extra-chromosomal DNA within the cell?

Mitochondria

What is the size of the human mitochondrial DNA (mtDNA) in base pairs?

16,569 bp

How many mtDNA molecules are present in each human cell?

Hundreds

What is the role of human mtDNA in protein synthesis?

Encodes 13 of the 89 subunits of the mitochondrial respiratory chain

How is mitochondrial genetics different from Mendelian genetics?

Uniparental inheritance of disease mutations

How many copies of mtDNA are present in each mitochondrion?

Two to 10

How is mtDNA inherited?

Maternally

What is heteroplasmy?

A mixture of mutant and normal mtDNAs

Do mtDNA recombine?

No

What is replicative segregation in relation to mtDNA?

The process of giving pure genotypes of mtDNA during division

Test your knowledge of the genetics of mitochondrial disorders with this quiz. Learn about the unique characteristics of mitochondrial DNA and its dual genetic control. Explore the role of mitochondria in human cells and understand the implications of mitochondrial disorders.

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