Mitochondria and Cellular Respiration

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Questions and Answers

How many molecules of ATP are produced from one complete turn of the Krebs cycle?

  • 1 molecule (correct)
  • 4 molecules
  • 3 molecules
  • 2 molecules

Which of the following products is generated in the highest quantity during the complete breakdown of one glucose molecule through glycolysis and the Krebs cycle?

  • Reduced NAD (correct)
  • CO2
  • Reduced FAD
  • ATP

During the Krebs cycle, how many molecules of CO2 are released for each glucose molecule metabolized?

  • 8 molecules
  • 4 molecules (correct)
  • 2 molecules
  • 6 molecules

Which compound is not produced during the glycolytic pathway?

<p>Carbon dioxide (CO2) (B)</p> Signup and view all the answers

How many turns of the Krebs cycle occur per glucose molecule during its metabolism?

<p>2 turns (C)</p> Signup and view all the answers

What is the primary product of anaerobic respiration in muscles?

<p>Lactic Acid (A)</p> Signup and view all the answers

How many ATP molecules are produced during anaerobic respiration?

<p>2 ATP (B)</p> Signup and view all the answers

Which of the following is a product of ethanol fermentation in yeast?

<p>Ethanol (C)</p> Signup and view all the answers

Where does aerobic respiration primarily occur in eukaryotic cells?

<p>Mitochondria (C)</p> Signup and view all the answers

What is the byproduct of aerobic respiration?

<p>Carbon Dioxide and Water (A)</p> Signup and view all the answers

What is produced during alcoholic fermentation?

<p>Ethanol, Carbon dioxide, and energy (A)</p> Signup and view all the answers

What type of respiration occurs in the absence of oxygen?

<p>Anaerobic respiration (D)</p> Signup and view all the answers

Which type of fermentation occurs in mammalian muscle tissue?

<p>Lactic acid fermentation (A)</p> Signup and view all the answers

What is the byproduct of glucose breakdown during lactic acid fermentation?

<p>Lactic acid (B)</p> Signup and view all the answers

Which organism primarily undergoes alcoholic fermentation?

<p>Yeast (C)</p> Signup and view all the answers

How many molecules of NADH are produced in the initial stages of anaerobic respiration?

<p>2 (C)</p> Signup and view all the answers

In anaerobic respiration, what is the main purpose of fermentation?

<p>To regenerate NAD+ and continue ATP production (B)</p> Signup and view all the answers

Which molecule is not a product of alcoholic fermentation?

<p>Lactic acid (D)</p> Signup and view all the answers

What is one function of the outer smooth membrane of the mitochondria?

<p>To allow entry of small molecules needed for cellular respiration (C)</p> Signup and view all the answers

What structure within the mitochondria contains ribosomes and DNA?

<p>Matrix (D)</p> Signup and view all the answers

Which metabolic process occurs in the cytoplasm?

<p>Glycolysis (A)</p> Signup and view all the answers

What role do the stalked particles found in the cristae serve?

<p>Facilitate ATP production using respiratory enzymes (B)</p> Signup and view all the answers

Which statement accurately describes the inner folded membrane of the mitochondria?

<p>It is folded to form structures called cristae. (B)</p> Signup and view all the answers

What are cristae primarily involved in?

<p>Increasing the surface area for respiration reactions (A)</p> Signup and view all the answers

What type of enzymes are primarily found in the mitochondrial matrix?

<p>Respiratory enzymes (B)</p> Signup and view all the answers

What characterizes the mitochondrial DNA compared to nuclear DNA?

<p>It is capable of coding for proteins independently. (A)</p> Signup and view all the answers

What is the primary energy yield from glycolysis during anaerobic respiration?

<p>2 ATP (C)</p> Signup and view all the answers

In lactic acid fermentation, which compound acts as the final hydrogen acceptor?

<p>Pyruvate (C)</p> Signup and view all the answers

What does lactate convert back into once oxygen supply is resumed?

<p>Pyruvate (D)</p> Signup and view all the answers

What is the fate of lactate after it is produced during anaerobic respiration?

<p>It is transported to the liver where it can be stored as glycogen. (C)</p> Signup and view all the answers

What is the reason for muscle fatigue and cramps during anaerobic respiration?

<p>Accumulation of lactic acid (C)</p> Signup and view all the answers

What term describes the extra oxygen needed to break down lactate after exercise?

<p>Oxygen debt (A)</p> Signup and view all the answers

What is the primary reason anaerobic respiration is used by muscles?

<p>To provide ATP when oxygen supply is inadequate (D)</p> Signup and view all the answers

Why are enzymes crucial in metabolic pathways?

<p>They speed up reactions by lowering activation energy. (B)</p> Signup and view all the answers

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Study Notes

Mitochondria Structure

  • Double membrane: Outer smooth membrane is permeable to small molecules needed for cellular respiration (e.g., pyruvate). The inner folded membrane forms finger-like cristae projecting into the matrix.
  • Cristae: Contain stalked particles which contain respiratory enzymes.
  • Matrix: Contains ribosomes and DNA. Also contains soluble enzymes for cellular respiration.

Stages of Respiration

  • Glycolysis: Takes place in the cytoplasm.
  • Kreb's cycle (citric acid cycle/ tricarboxylic acid cycle): Takes place in the matrix of mitochondria.
    • Each turn of the Krebs cycle produces:
      • 2 molecules of CO2
      • 1 molecule of ATP
      • 3 molecules of reduced NAD
      • 1 molecule of reduced FAD
  • ATP (adenosine triphosphate) synthesis by Chemiosmosis: Occurs in the inner mitochondrial membrane. Protons (H+) are pumped across the membrane from the matrix to the intermembrane space, creating a concentration gradient. This gradient drives the movement of protons back into the matrix through ATP synthase, generating ATP.

Anaerobic Respiration

  • Occurs in the absence of oxygen.
  • Two types:
    • Alcoholic fermentation: Occurs in yeast and roots of plants in waterlogged soil. Produces ethanol, carbon dioxide, and energy (glucose -> ethanol + carbon dioxide + energy).
    • Lactic acid fermentation: Occurs in mammalian muscle tissue. Produces lactic acid and energy (glucose -> lactic acid + energy).

Importance of Anaerobic Respiration in Muscles

  • When oxygen supply fails to meet muscle demand, muscles respire anaerobically.
  • Lactic acid produced lowers the pH and can inhibit muscle enzymes, causing muscle fatigue and cramps.
  • Once oxygen supply is resumed, lactate is converted back into pyruvate for the Krebs cycle or transported to the liver for breakdown or storage as glycogen.
  • Extra oxygen needed to breakdown lactate is known as "oxygen debt".

Metabolic Pathways and Enzymes

  • Many cellular respiration reactions occur through metabolic pathways where each step is catalyzed by a specific enzyme.
  • Enzymes lower the activation energy required for the reactions to take place.
  • Glucose is broken down into pyruvate through a series of steps, each with a specific enzyme.

Cellular Respiration Flowchart

  • Glucose is initially broken down via glycolysis to produce pyruvate.
  • In anaerobic conditions, pyruvate is further broken down to either ethanol and CO2 (alcoholic fermentation) or lactic acid (lactic acid fermentation).
  • In aerobic conditions, pyruvate enters the mitochondria to undergo the Krebs cycle and oxidative phosphorylation.
  • This process generates a significant amount of ATP, CO2, and water.

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