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Questions and Answers
What happens to pyruvate when molecular oxygen is limiting?
What happens to pyruvate when molecular oxygen is limiting?
Where does non-shivering thermogenesis mainly occur in the body?
Where does non-shivering thermogenesis mainly occur in the body?
What role do mitochondria play in calcium homeostasis?
What role do mitochondria play in calcium homeostasis?
How do mitochondria regulate cell division?
How do mitochondria regulate cell division?
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What is the structural feature of the inner mitochondrial membrane?
What is the structural feature of the inner mitochondrial membrane?
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What function do mitochondria serve in hormonal signaling?
What function do mitochondria serve in hormonal signaling?
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In what manner do mitochondria reproduce?
In what manner do mitochondria reproduce?
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What is the significance of mitochondrial genomic DNA (mtDNA)?
What is the significance of mitochondrial genomic DNA (mtDNA)?
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What is the primary function of mitochondria in cells?
What is the primary function of mitochondria in cells?
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Which of the following statements about mitochondria is true?
Which of the following statements about mitochondria is true?
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In which cellular process is pyruvate converted to acetyl-CoA?
In which cellular process is pyruvate converted to acetyl-CoA?
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Which organism is described as having no true mitochondria?
Which organism is described as having no true mitochondria?
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What is the main site of the respiratory chain in mitochondria?
What is the main site of the respiratory chain in mitochondria?
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What is the significance of the proton gradient in mitochondria?
What is the significance of the proton gradient in mitochondria?
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Which metabolic pathway occurs in the mitochondrial matrix?
Which metabolic pathway occurs in the mitochondrial matrix?
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What is the primary type of ATP-generating enzyme found in mitochondria?
What is the primary type of ATP-generating enzyme found in mitochondria?
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What is the primary role of chloroplasts in plant cells?
What is the primary role of chloroplasts in plant cells?
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Which type of plastid is responsible for synthesizing and storing pigments?
Which type of plastid is responsible for synthesizing and storing pigments?
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What do gerontoplasts primarily signify in chloroplast development?
What do gerontoplasts primarily signify in chloroplast development?
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Which plastids are known to store starch?
Which plastids are known to store starch?
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What is the primary function of the outer membrane of the mitochondrion?
What is the primary function of the outer membrane of the mitochondrion?
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What triggers phototrophic electron transport in chloroplasts?
What triggers phototrophic electron transport in chloroplasts?
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Which feature is unique to the inner membrane of the mitochondrion?
Which feature is unique to the inner membrane of the mitochondrion?
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How do chloroplasts contribute to plant defense mechanisms?
How do chloroplasts contribute to plant defense mechanisms?
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Which of the following plastids can differentiate into other types?
Which of the following plastids can differentiate into other types?
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What is the main role of the matrix within the mitochondrion?
What is the main role of the matrix within the mitochondrion?
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In which organelle is the synthesis of fatty acids primarily conducted?
In which organelle is the synthesis of fatty acids primarily conducted?
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Which component is NOT found in human mitochondrial DNA?
Which component is NOT found in human mitochondrial DNA?
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Which statement about mitochondrial ribosomes is accurate?
Which statement about mitochondrial ribosomes is accurate?
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Which molecule is primarily responsible for establishing the proton gradient in the intermembrane space of mitochondria?
Which molecule is primarily responsible for establishing the proton gradient in the intermembrane space of mitochondria?
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What happens to a cell when the outer membrane of the mitochondrion is breached?
What happens to a cell when the outer membrane of the mitochondrion is breached?
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What is the size of the human mitochondrial genome approximately?
What is the size of the human mitochondrial genome approximately?
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What are the main pigments found in chloroplasts of the Streptophyta?
What are the main pigments found in chloroplasts of the Streptophyta?
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What is the correct structure found in chloroplasts that is comprised of stacks of thylakoids?
What is the correct structure found in chloroplasts that is comprised of stacks of thylakoids?
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Which of the following statements is true about thylakoids?
Which of the following statements is true about thylakoids?
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What term is used to describe the stack of thylakoids in chloroplasts?
What term is used to describe the stack of thylakoids in chloroplasts?
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What element separates the inner and outer membranes of chloroplasts?
What element separates the inner and outer membranes of chloroplasts?
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Which of the following colors is represented by the prefix 'chloro-' in scientific terminology?
Which of the following colors is represented by the prefix 'chloro-' in scientific terminology?
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Which pigments are used by chloroplasts of the Chlorophyta?
Which pigments are used by chloroplasts of the Chlorophyta?
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Which structure is described as containing plastoglobulus and starch granules?
Which structure is described as containing plastoglobulus and starch granules?
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What is the primary function of the cristae in mitochondria?
What is the primary function of the cristae in mitochondria?
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Which type of plastid is formed from chloroplasts?
Which type of plastid is formed from chloroplasts?
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Which of the following pigments are utilized by cyanoplasts of the Glaucophyta?
Which of the following pigments are utilized by cyanoplasts of the Glaucophyta?
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What is a role of cardiolipin in mitochondrial membranes?
What is a role of cardiolipin in mitochondrial membranes?
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Where are ribosomes located within mitochondria?
Where are ribosomes located within mitochondria?
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Which carotenoid does not contain oxygen?
Which carotenoid does not contain oxygen?
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What are the key differences between mtDNA and cpDNA?
What are the key differences between mtDNA and cpDNA?
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What type of non-phototrophic plastid is involved in lipid storage?
What type of non-phototrophic plastid is involved in lipid storage?
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Flashcards
Mitochondria: Primary Role
Mitochondria: Primary Role
The main function of mitochondria is to generate energy for the cell through cellular respiration.
Mitochondrial Respiration Site
Mitochondrial Respiration Site
The process where mitochondria generate energy occurs on the inner membrane of the mitochondria.
Proton-Motive Force in Mitochondria
Proton-Motive Force in Mitochondria
Mitochondrial respiration involves a proton gradient across the inner membrane, driving ATP production by ATP synthase.
Kreb's Cycle Location
Kreb's Cycle Location
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Mitochondrial Number Variability
Mitochondrial Number Variability
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Organisms Without Mitochondria
Organisms Without Mitochondria
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Mitochondria Prevalence in Eukarya
Mitochondria Prevalence in Eukarya
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Mitochondrial Origin
Mitochondrial Origin
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Fermentation in Mitochondria
Fermentation in Mitochondria
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Non-Shivering Thermogenesis
Non-Shivering Thermogenesis
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Calcium Homeostasis in Mitochondria
Calcium Homeostasis in Mitochondria
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Mitochondria in Cell Division
Mitochondria in Cell Division
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Mitochondrial Role in Apoptosis
Mitochondrial Role in Apoptosis
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Mitochondrial Steroid Biosynthesis
Mitochondrial Steroid Biosynthesis
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Heme Production in Mitochondria
Heme Production in Mitochondria
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Mitochondrial DNA (mtDNA)
Mitochondrial DNA (mtDNA)
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Outer Mitochondrial Membrane: Composition
Outer Mitochondrial Membrane: Composition
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Outer Membrane: Importance
Outer Membrane: Importance
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Inner Mitochondrial Membrane: Function
Inner Mitochondrial Membrane: Function
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Cardiolipin in Inner Membrane
Cardiolipin in Inner Membrane
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Intermembrane Space: Function
Intermembrane Space: Function
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Mitochondrial Matrix: Location and Function
Mitochondrial Matrix: Location and Function
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mtDNA: Disease Association
mtDNA: Disease Association
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What are plastids?
What are plastids?
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What are chloroplasts?
What are chloroplasts?
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What are rhodoplasts?
What are rhodoplasts?
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What are cyanoplasts?
What are cyanoplasts?
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What are etioplasts?
What are etioplasts?
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What are gerontoplasts?
What are gerontoplasts?
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What are chromoplasts?
What are chromoplasts?
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What are leucoplasts?
What are leucoplasts?
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Stroma
Stroma
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Granum (plural: grana)
Granum (plural: grana)
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Thylakoid
Thylakoid
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Lumen
Lumen
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Chloroplasts
Chloroplasts
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Rhodoplasts
Rhodoplasts
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Lamella or fret
Lamella or fret
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Chloroplast DNA (cpDNA)
Chloroplast DNA (cpDNA)
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What are cristae in mitochondria?
What are cristae in mitochondria?
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What is the key role of mitochondria?
What is the key role of mitochondria?
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Describe the structure of the outer mitochondrial membrane.
Describe the structure of the outer mitochondrial membrane.
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What is the function of the inner mitochondrial membrane?
What is the function of the inner mitochondrial membrane?
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What is mtDNA?
What is mtDNA?
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What is the main function of chloroplasts?
What is the main function of chloroplasts?
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What is the structure of the inner membrane of chloroplasts?
What is the structure of the inner membrane of chloroplasts?
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Describe the stroma of a chloroplast.
Describe the stroma of a chloroplast.
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Study Notes
Mitochondria and Plastids
- Mitochondria and plastids are important cellular organelles with diverse roles
- Popular science books discussing these organelles include "The Vital Question: Why Is Life the Way It Is?" by Lane (2015), "Power, Sex, Suicide: Mitochondria and the Meaning of Life" by Lane (2005), "Oxygen: The Molecule that Made the World" by Lane (2002), and "Eating the Sun: How Plants Power the Planet" by Morton (2009).
Mitochondria
- Most eukaryotic cells possess mitochondria, contributing significantly to cell volume (up to 25%).
- The number of mitochondria per cell varies (e.g. >2,000 per hepatocyte in humans).
- Some eukaryotic organisms lack mitochondria
- Examples include: unicellular flagellate Monocercomonoides exilis and the multicellular Henneguya zschokkei
- Mitochondria are the site of critical cellular processes.
Mitochondria Roles
- Respiratory chain: The inner mitochondrial membrane houses the electron transport chain, generating a proton-motive force crucial for ATP synthesis.
- Krebs cycle: Pyruvate, from glycolysis, is converted to acetyl-CoA within the mitochondrial matrix, initiating the Krebs cycle.
- Fermentation: Without sufficient oxygen, the Krebs cycle slows, and pyruvate is fermented into lactate, generating NADH.
- Non-shivering thermogenesis: In brown adipose tissue, mitochondria can uncouple ATP synthesis from the proton gradient generating heat.
- Calcium homeostasis: Mitochondria maintain calcium ion levels, crucial for cellular signaling.
- Regulation of cell division: ATP and NADPH produced in mitochondria are necessary for cell biomass generation and division.
- Other roles: Mitochondria also regulate apoptosis and participate in steroid, heme cofactor biosynthesis and hormonal signalling
Mitochondrial Structures
- Outer membrane: Contains porins, crucial for controlling passage of molecules.
- Inner membrane: Highly folded to increase surface area and houses the respiratory chain proteins.
- Intermembrane space: The region between the outer and inner membranes.
- Matrix: The inner compartment of the mitochondrion containing ribosomes, mtDNA, and enzymes of the Krebs cycle.
Mitochondrial Matrix
- The matrix holds about 60% of the total soluble protein content, including pyruvate oxidation and Krebs cycle enzymes (excluding membrane-bound succinate dehydrogenase).
- The matrix houses mitochondrial ribosomes(70s), comprising 50S and 30S subunits and contains mitochondrial DNA (mtDNA).
- mtDNA contains genes for mitochondrial proteins and components of the oxidative phosphorylation system
Plastids
- Plastids are double-membrane-bound organelles found in plants and algae.
- Plastids include chloroplasts, which enable photosynthesis, and other types of plastids like chromoplasts and leucoplasts.
Chloroplasts
- Site of phototrophic electron transport.
- Chloroplasts are the site of photosynthesis, where light energy is converted into chemical energy (ATP and NADPH).
- Plant Immunity: Chloroplasts produce chemicals that trigger apoptosis to defend against pathogens.
- Fatty acid biosynthesis: Chloroplasts produce all plant-cell fatty acids.
- Sugar and starch biosynthesis: Chloroplasts convert glucose into sucrose and starches.
Chloroplast Membranes
- Outer membrane: Similar composition to other membranes composed of phospholipids and galactolipids.
- Inner membrane: Composed of galactolipids, phospholipids, and sulfolipids. Closely associated with light-harvesting systems.
Chloroplast Stroma
- The stroma is equivalent to the cytoplasm in bacterial cells
- Contains plastoglobuli (lipid and protein structures) and enzymes involved in the Calvin-Benson-Bassham cycle (CO2 fixation).
- Contains cpDNA (chloroplast DNA)
Chromoplasts
- Chromoplasts are plastids involved in fruit ripening and producing pigments in flowers
- They originate from chloroplasts and produce carotenoids, anthocyanins, and other pigments.
Chloroplasts vs. Rhodoplasts vs. Cyanoplasts
- Different types of plastids have distinct pigment compositions that influence their functions.
- Chloroplasts in different plant groups use different combinations of chlorophyll and carotenoid pigments to perform photosynthesis.
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Test your knowledge on the fascinating roles of mitochondria in cellular processes, including respiration, calcium homeostasis, and thermogenesis. This quiz covers a variety of topics related to mitochondrial function and structure, ideal for biology students and enthusiasts.