Migraines, Cluster and Tension Headaches
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Questions and Answers

Which of the following best describes the pain associated with tension-type headaches?

  • Dull, aching, or pressure-like pain, typically bilateral (correct)
  • Sharp, stabbing pain lasting only a few seconds
  • Excruciating, severe unilateral pain centered around one eye
  • Intense throbbing pain accompanied by nausea and vomiting

Which of the following is NOT typically associated with cluster headaches?

  • Aura (correct)
  • Lacrimation
  • Rhinorrhea
  • Severe unilateral pain

A patient reports experiencing visual disturbances before the onset of a headache. This is most indicative of which phase of a migraine?

  • Headache Phase
  • Prodrome
  • Postdrome
  • Aura (correct)

A patient says they experience a headache that occurs multiple times a day for a period of several weeks, with each episode lasting about an hour. Which type of headache is most likely?

<p>Cluster headache (B)</p> Signup and view all the answers

Photophobia or phonophobia may be present with tension-type headaches, but not both simultaneously. Which of the following scenarios aligns with this?

<p>A patient experiences sensitivity to light but not sound during their headache. (C)</p> Signup and view all the answers

Which neuropeptide is MOST associated with the vasodilation of dural blood vessels during a migraine?

<p>Calcitonin Gene-Related Peptide (CGRP) (C)</p> Signup and view all the answers

What neurological phenomenon is thought to initiate the activation of the trigeminal nerve in migraines?

<p>Cortical Spreading Depression (CSD) (B)</p> Signup and view all the answers

Which of the following is LEAST likely to be a trigger for migraines?

<p>Consistent sleep schedule (B)</p> Signup and view all the answers

Cluster headaches are characterized by their cyclical nature. Which structure in the brain is MOST responsible for this pattern?

<p>Suprachiasmatic Nucleus (SCN) (C)</p> Signup and view all the answers

Which autonomic imbalance is characteristic of cluster headaches?

<p>Sympathetic underactivity and parasympathetic overactivity (D)</p> Signup and view all the answers

What is the primary origin of pain believed to be in tension-type headaches?

<p>Muscle tension and myofascial trigger points (C)</p> Signup and view all the answers

Why is the trigeminal nerve implicated in all three headache syndromes—migraine, cluster, and tension-type?

<p>It plays a critical role in relaying pain signals from the head and face, and interacts with both vascular and muscular systems. (B)</p> Signup and view all the answers

A patient reports unilateral throbbing headaches accompanied by nausea, vomiting, and extreme sensitivity to light and sound. Symptoms worsen with physical activity. Which prophylactic intervention MOST directly addresses the underlying mechanism of their likely condition?

<p>Administering a CGRP antagonist medication. (B)</p> Signup and view all the answers

Flashcards

Prodromal Phase

Warning signs (yawning, fatigue, mood changes, cravings) that some migraine patients experience before a headache.

Migraine Aura

Neurological symptoms (visual, sensory, speech) experienced by some migraineurs before or during a headache.

Postdrome

The period after a migraine where individuals feel drained or fatigued.

Cluster Headache

Excruciating, severe unilateral pain, often around one eye, with autonomic features.

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Tension-Type Headache

Dull, aching, pressure-like pain, typically bilateral, often linked to muscle tension.

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Migraine Cause

Activation of the trigeminal nerve and trigeminovascular system, often triggered by cortical spreading depression (CSD).

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Migraine Mechanisms

Vasodilation of dural blood vessels, release of neuropeptides (CGRP, substance P, VIP), and sterile inflammation of the meninges.

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Migraine Triggers

Stress, specific foods, weather changes, and hormonal fluctuations.

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Cluster Headache Cause

Activation of the trigeminal autonomic reflex, linked to the hypothalamus (specifically the suprachiasmatic nucleus, SCN).

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Cluster Headache Processes

Sympathetic underactivity and parasympathetic overactivity, trigeminal nerve activation leading to facial pain, tearing, and nasal congestion.

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Cluster Headache Triggers

Alcohol consumption, sleep disturbances, and irregular sleep-wake cycles.

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Tension-Type Headache Cause

Muscle tension and myofascial trigger points, mainly in the head and neck.

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Tension-Type Headache Mechanisms

Increased pericranial muscle tension, abnormal central pain processing, and heightened sensitivity in pain pathways (especially within the trigeminal nerve system).

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Study Notes

  • Causes and manifestations of migraines, cluster headaches, and tension-type headaches.

Migraines

  • Primary mechanism involves activation of the trigeminal nerve (cranial nerve V) and the trigeminovascular system
  • Cortical Spreading Depression (CSD) triggers activation by self-propagating wave of neuronal and glial depolarization
  • Key factors: vasodilation of dural blood vessels
  • Other key factirs are release of neuropeptides, sterile inflammation of the meninges and sensitization of pain receptors
  • External triggers include stress, specific foods, weather changes, and hormonal fluctuations
  • Symptoms: throbbing/pulsating pain, typically unilateral but can be bilateral
  • Often accompanied by nausea, vomiting, photophobia, and phonophobia
  • Prodromal Phase: patients experience warning signs like yawning, fatigue, mood changes, or cravings before headache onset
  • Aura affects about 20-30% of migraineurs and is characterized by visual disturbances (e.g., scintillating scotomas), sensory changes, or speech difficulties
  • Postdrome: after the headache, individuals may feel drained or fatigued for hours to days

Cluster Headaches

  • Underlying mechanism involves activation of the trigeminal autonomic reflex and pathways linking the hypothalamus to the trigeminal nerve
  • The suprachiasmatic nucleus (SCN) in the hypothalamus regulates circadian rhythms
  • Key processes include sympathetic underactivity and parasympathetic overactivity
  • Also Trigeminal nerve activation is included in the key processes, which leads to facial pain, tearing, and nasal congestion
  • Triggers include alcohol consumption, sleep disturbances, and irregular sleep-wake cycles
  • Symptoms: excruciating, severe unilateral pain, often centered around or behind one eye.
  • Autonomic Features: lacrimation (tearing), nasal congestion, rhinorrhea (runny nose), ptosis (drooping eyelid), and conjunctival injection (redness)
  • Attacks frequently follow a daily or seasonal pattern
  • Each attack typically lasts 15 minutes to 3 hours and can occur multiple times per day during a cluster period

Tension-Type Headaches

  • Believed to originate from muscle tension and myofascial trigger points, typically in the head and neck
  • Mechanisms involve increased pericranial muscle tension and tenderness
  • Also mechanisms include Abnormal central pain processing and heightened sensitivity in pain pathways, especially within the trigeminal nerve system
  • Emotional stress, poor posture, fatigue, and lack of sleep are common triggers
  • Symptoms: dull, aching, or pressure-like pain, typically bilateral
  • Pain Characteristics: described as a tight band around the head, involving the forehead, temples, and/or back of the neck
  • Often associated with muscle tension in the neck, scalp, or shoulders
  • Unlike migraines, there is typically no nausea, vomiting, or aura.
  • Photophobia or phonophobia may be present, but not both simultaneously

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Description

Explore causes & symptoms of headaches - migraines, cluster, tension-type. Migraines involve trigeminal nerve activation, cortical spreading depression, & triggers like stress & foods. Symptoms: throbbing pain, nausea, light/sound sensitivity, with possible auras or prodromes.

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