Podcast
Questions and Answers
What is the brand name for Midazolam?
What is the brand name for Midazolam?
What classification does Midazolam fall under?
What classification does Midazolam fall under?
Amnesic Agent, Sedative/Hypnotic, Anticonvulsant, Benzodiazepine, Anti-anxiety
The MOA of Versed involves binding to __________.
The MOA of Versed involves binding to __________.
Benzodiazepine receptors
Which of the following are indications for Versed?
Which of the following are indications for Versed?
Signup and view all the answers
What is NOT a contraindication for Versed?
What is NOT a contraindication for Versed?
Signup and view all the answers
Name two common side effects of Versed.
Name two common side effects of Versed.
Signup and view all the answers
Which patients require precautions when using Versed?
Which patients require precautions when using Versed?
Signup and view all the answers
What should be avoided when administering Versed?
What should be avoided when administering Versed?
Signup and view all the answers
What are the routes of administration for Versed?
What are the routes of administration for Versed?
Signup and view all the answers
What is the onset time for Versed when administered IVP?
What is the onset time for Versed when administered IVP?
Signup and view all the answers
What is the initial dosage of Versed for adult pre-cardioversion?
What is the initial dosage of Versed for adult pre-cardioversion?
Signup and view all the answers
Study Notes
Midazolam Overview
- Brand Name: Versed
- Classification:
- Amnesic Agent
- Sedative/Hypnotic
- Anticonvulsant
- Benzodiazepine
- Anti-anxiety
Mechanism of Action
- Binds to benzodiazepine receptors
- Enhances GABA, leading to:
- Decreased agitation
- Muscle relaxation
- Induction of sleep at high doses
Indications
- Treatment of seizures
- Premedication for synchronized cardioversion/transcutaneous pacing (TCP)
- One of the options for Rapid Sequence Intubation (RSI) premedication
- Management of anxiety disorders
Contraindications
- Not to be used in acute narrow-angle glaucoma
- Should be avoided in shock due to hypovolemia
- Contraindicated in cases of alcohol or drug intoxication
Side Effects
- Cardiovascular:
- Bradycardia
- Hypotension
- Rebound tachycardia
- Neurological:
- Amnesia
- Drowsiness
- Agitation
- Altered Level of Consciousness (ALOC)
- Respiratory:
- Potential respiratory depression or arrest
- Gastrointestinal:
- Nausea and vomiting (N/V)
Precautions
- Caution in elderly patients with impaired respiratory function
- Use carefully in patients with:
- Renal failure
- Liver failure
- Chronic Obstructive Pulmonary Disease (COPD)
Drug Interactions
- Enhanced effects when combined with other CNS depressants or benzodiazepines
Routes of Administration
- Administered via:
- IV Push (IVP)
- Intraosseous (IO)
- Intramuscular (IM)
- Intranasal (IN)
Onset and Duration
- Rapid onset:
- 1-5 minutes via IVP/IO/IN
- 5-15 minutes via IM
- Duration of effect is approximately 2-6 hours
Dosages
-
Adult:
- Pre-cardioversion or TCP: 1.0 - 2.5 mg slow IVP/IO/IN
- For seizures: 0.1 mg/kg slow IVP/IO/IN or 0.2 mg/kg IM, max 5 mg
-
Pediatric:
- For seizures: 0.1 mg/kg slow IVP/IO/IN or 0.2 mg/kg IM, max 5 mg
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
Description
Test your knowledge on Midazolam, also known as Versed, through these flashcards. Learn about its classification, mechanism of action, and indications in a fun and interactive way. Perfect for students and professionals in the medical field!
