23 Questions
What is the main function of anaphase B in mitosis?
Movement of spindle poles apart
What is the role of securin in mitosis?
Inhibiting separase
How does the spindle assessment checkpoint control mitosis?
By inhibiting APC
During telophase, what happens to nuclear pore proteins and nuclear lamins?
They dephosphorylate
What initiates cleavage furrow formation during cytokinesis?
Central spindle signaling cell cortex
What is the primary role of dynein in mitosis?
Moving spindle poles apart
What is the role of tethering proteins in vesicle trafficking?
Assist in firmly docking the vesicle before fusion
In the secretory pathway, what is the destination after Golgi apparatus for proteins before exocytosis?
Plasma membrane
Which organelle is responsible for sorting and packaging proteins destined for regulated secretion?
Trans Golgi network
What triggers apoptosis in response to protein misfolding in the ER?
Unfolded protein response
What is a characteristic feature of late endosomes compared to early endosomes?
They are closer to the nucleus
Which type of endocytosis involves clathrin-coated pits and vesicles?
Receptor-mediated endocytosis
What distinguishes the constitutive exocytosis pathway from the regulated exocytosis pathway?
The requirement of a signal sequence
What occurs when Cdc6 binds to the origin recognition complex (ORC) during the G1 phase of the cell cycle?
Promotes assembly of proteins for replication fork formation
What is the function of Cdc25 in the cell cycle control system?
Removes inhibitory phosphate from M-Cdk
What triggers the breakdown of the nuclear envelope in prometaphase of mitosis?
Phosphorylation of nuclear pore proteins
What is the role of cohesin proteins during mitosis?
Holds sister chromatids together
What effect does the accumulation of cyclins have on the cell cycle?
Delays entry into M phase
Which protein is responsible for activating transcription regulators important for initiating gene transcription in the cell cycle?
Rb protein
What happens when S-Cdk is activated during the S phase of the cell cycle?
Blocks re-replication of DNA
"Wee1" is involved in regulating which phase of the cell cycle?
"M Phase"
"Anaphase-promoting complex (APC)" is responsible for which crucial function during mitosis?
"Tagging cyclins with ubiquitin"
"Mitogens" promote the production of which cyclins that stimulate cell division?
"G1 Cyclins"
Explore the dynamic processes of microtubules and the distinct movements that occur during anaphase in cell division. Learn about the actions of microtubule motor proteins, the separation of sister chromatids, and the roles of protease separase and securin. Delve into the mechanisms of Anaphase A and Anaphase B.
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