Microtubule Dynamics and Anaphase Processes
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Questions and Answers

What is the main function of anaphase B in mitosis?

  • Activation of APC
  • Movement of spindle poles apart (correct)
  • Anchoring of dynein on cell cortex
  • Shortening of kinetochore microtubules
  • What is the role of securin in mitosis?

  • Moving spindle poles apart
  • Activating the APC
  • Inhibiting separase (correct)
  • Shortening kinetochore microtubules
  • How does the spindle assessment checkpoint control mitosis?

  • By moving spindle poles apart
  • By activating APC
  • By inhibiting APC (correct)
  • By dephosphorylating nuclear pore proteins
  • During telophase, what happens to nuclear pore proteins and nuclear lamins?

    <p>They dephosphorylate</p> Signup and view all the answers

    What initiates cleavage furrow formation during cytokinesis?

    <p>Central spindle signaling cell cortex</p> Signup and view all the answers

    What is the primary role of dynein in mitosis?

    <p>Moving spindle poles apart</p> Signup and view all the answers

    What is the role of tethering proteins in vesicle trafficking?

    <p>Assist in firmly docking the vesicle before fusion</p> Signup and view all the answers

    In the secretory pathway, what is the destination after Golgi apparatus for proteins before exocytosis?

    <p>Plasma membrane</p> Signup and view all the answers

    Which organelle is responsible for sorting and packaging proteins destined for regulated secretion?

    <p>Trans Golgi network</p> Signup and view all the answers

    What triggers apoptosis in response to protein misfolding in the ER?

    <p>Unfolded protein response</p> Signup and view all the answers

    What is a characteristic feature of late endosomes compared to early endosomes?

    <p>They are closer to the nucleus</p> Signup and view all the answers

    Which type of endocytosis involves clathrin-coated pits and vesicles?

    <p>Receptor-mediated endocytosis</p> Signup and view all the answers

    What distinguishes the constitutive exocytosis pathway from the regulated exocytosis pathway?

    <p>The requirement of a signal sequence</p> Signup and view all the answers

    What occurs when Cdc6 binds to the origin recognition complex (ORC) during the G1 phase of the cell cycle?

    <p>Promotes assembly of proteins for replication fork formation</p> Signup and view all the answers

    What is the function of Cdc25 in the cell cycle control system?

    <p>Removes inhibitory phosphate from M-Cdk</p> Signup and view all the answers

    What triggers the breakdown of the nuclear envelope in prometaphase of mitosis?

    <p>Phosphorylation of nuclear pore proteins</p> Signup and view all the answers

    What is the role of cohesin proteins during mitosis?

    <p>Holds sister chromatids together</p> Signup and view all the answers

    What effect does the accumulation of cyclins have on the cell cycle?

    <p>Delays entry into M phase</p> Signup and view all the answers

    Which protein is responsible for activating transcription regulators important for initiating gene transcription in the cell cycle?

    <p>Rb protein</p> Signup and view all the answers

    What happens when S-Cdk is activated during the S phase of the cell cycle?

    <p>Blocks re-replication of DNA</p> Signup and view all the answers

    "Wee1" is involved in regulating which phase of the cell cycle?

    <p>&quot;M Phase&quot;</p> Signup and view all the answers

    "Anaphase-promoting complex (APC)" is responsible for which crucial function during mitosis?

    <p>&quot;Tagging cyclins with ubiquitin&quot;</p> Signup and view all the answers

    "Mitogens" promote the production of which cyclins that stimulate cell division?

    <p>&quot;G1 Cyclins&quot;</p> Signup and view all the answers

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