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Questions and Answers
What is an example of a reservoir host for a pathogen?
What is an example of a reservoir host for a pathogen?
Which of the following correctly defines normal flora?
Which of the following correctly defines normal flora?
What must occur for an infection to develop according to the Chain of Infection?
What must occur for an infection to develop according to the Chain of Infection?
What can serve as a portal of exit for pathogens?
What can serve as a portal of exit for pathogens?
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Which type of microorganism specifically requires oxygen to survive?
Which type of microorganism specifically requires oxygen to survive?
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What is a common portal of entry for pathogens into a new host?
What is a common portal of entry for pathogens into a new host?
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Which one of the following is a characteristic of communicable diseases?
Which one of the following is a characteristic of communicable diseases?
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Which of the following is a sign of a generalized infection?
Which of the following is a sign of a generalized infection?
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What is a characteristic of the environment preferred by many microorganisms?
What is a characteristic of the environment preferred by many microorganisms?
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What defines a carrier in the context of infection control?
What defines a carrier in the context of infection control?
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What role does hydrochloric acid play in natural defense mechanisms?
What role does hydrochloric acid play in natural defense mechanisms?
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Which statement accurately describes acquired immunity?
Which statement accurately describes acquired immunity?
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How can the source of microorganisms be decreased?
How can the source of microorganisms be decreased?
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What is one method to prevent the transmission of microorganisms?
What is one method to prevent the transmission of microorganisms?
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What is the primary goal of medical asepsis?
What is the primary goal of medical asepsis?
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Which of the following describes a localized infection?
Which of the following describes a localized infection?
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What happens to antibodies developed through passive immunity over time?
What happens to antibodies developed through passive immunity over time?
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Which of the following practices is considered part of standard precautions?
Which of the following practices is considered part of standard precautions?
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What is the purpose of surgical asepsis?
What is the purpose of surgical asepsis?
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What is one of the main categories of isolation precautions?
What is one of the main categories of isolation precautions?
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Which type of body fluid is NOT included under standard precautions?
Which type of body fluid is NOT included under standard precautions?
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What practice should be avoided or done using a one-handed technique?
What practice should be avoided or done using a one-handed technique?
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The ultimate objective of using isolation precautions includes reducing what?
The ultimate objective of using isolation precautions includes reducing what?
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What type of asepsis involves procedures to eliminate pathogens from objects and areas?
What type of asepsis involves procedures to eliminate pathogens from objects and areas?
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Which mode of transmission is NOT associated with Hepatitis B virus infection?
Which mode of transmission is NOT associated with Hepatitis B virus infection?
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What is the primary route of transmission for Hepatitis C?
What is the primary route of transmission for Hepatitis C?
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What is a significant characteristic of Hepatitis D?
What is a significant characteristic of Hepatitis D?
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Which statement about HIV is true?
Which statement about HIV is true?
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Which of the following describes the spread of Tuberculosis (TB)?
Which of the following describes the spread of Tuberculosis (TB)?
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What defines a nosocomial infection?
What defines a nosocomial infection?
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How is Hepatitis A primarily transmitted?
How is Hepatitis A primarily transmitted?
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Which of the following statements is false regarding hepatitis infections?
Which of the following statements is false regarding hepatitis infections?
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Study Notes
Microorganisms
- Are very small living plants or animals, most are one-celled
- Cannot be seen with the naked eye
- Exist everywhere in the environment
- Can be aerobic (need oxygen) or anaerobic (do not need oxygen)
- Prefer warm, moist, dark environments with food sources
Infection
- Establishment and growth of microorganisms on or in a host
- Invasion and growth of microorganisms in body tissue that harm the cell tissue
Contagious or Communicable Disease
- Can be transmitted directly or indirectly from one person to another
Normal Flora
- Microorganisms that don’t cause disease
- Commonly reside in a particular environment on or in the body (skin, vagina, and intestines)
- Used in food and drug processing
- Destroy waste and contribute to environmental comfort
- E. coli is normal flora of the gastrointestinal tract, but can become pathogenic if it enters the bladder
Chain of Infection
- Consists of six elements that must be present for an infection to develop
Infectious Agent
- A pathogen must be present:
- Bacteria
- Viruses
- Fungi
- Rickettsia
- Protozoa
Reservoir Host
- The pathogen must have a place to live and grow
- Examples of reservoir hosts:
- Human body
- Contaminated water or food
- Animals
- Insects
- Birds
- Dead or decaying organic material
- Examples of reservoir hosts:
- Carrier: human or animal capable of transmitting the pathogen but have no signs of the disease
Portal of Exit
- The pathogen must be able to escape from the reservoir host
- Examples:
- Blood
- Urine
- Feces
- Breaks in the skin
- Wound drainage
- Body secretions (saliva, mucus, reproductive fluids)
- Examples:
Route of Transmission
- When the pathogen leaves the reservoir host through the portal of exit, it must have a way of being transmitted to a new host
- Examples:
- Air
- Food
- Insects
- Direct contact with an infected person
- Examples:
Portal of Entry
- The pathogen must have a way of entering the new host
- Common ports of entry:
- Mouth
- Nostrils
- Breaks in the skin
- Common ports of entry:
Susceptible Host
- An individual who has a large number of pathogens invading the body or does not have an adequate resistance to the invading pathogen will get the infectious disease
Signs and Symptoms of Infections
-
Generalized or systemic: affecting the whole body
- May cause: fever, headache, fatigue, vomiting, diarrhea, increased pulse and respirations
-
Localized: affecting one area of the body
- May cause: redness, swelling, warmth to the touch, drainage, pain
Defense Mechanisms
- Present to resist infections
-
Natural defenses:
- Cilia: respiratory tract that catch and move pathogens out of the body
- Coughing and sneezing: to propel pathogens outward
- Tears: contain chemicals to kill bacteria
- Hydrochloric acid in the stomach: destroys pathogens
- Mucous membranes: of the respiratory, reproductive, and digestive systems trap pathogens
- Fever: kills microorganisms
- Increase of leukocytes (white blood cells): to destroy pathogens
-
Acquired immunity
- Active immunity: individual develops antibodies, long term
- Passive immunity: individual injected with antibodies, short term
-
Natural defenses:
Breaking the Chain of Infection
- Breaking at least one link stops the infectious disease
- Practices and techniques used by health care professionals are designed to break the chain
How to Decrease the Source of Microorganisms
- Perform proper handwashing
- Decontaminate surfaces and equipment using:
- Antiseptics
- Disinfectants
- Sterilization
- Avoid contact with patients
How to Prevent the Transmission of Microorganisms
- Wear personal protective equipment (PPE):
- Caps
- Gloves
- Gowns
- Masks
- Booties
- Eye protection
- Follow isolation procedures when indicated
How to Maximize the Resistance of the Host
- Provide good hygiene
- Ensure proper nutrition and fluid intake
- Decrease stressors that weaken the immune response
Methods of Infection Control
-
Medical asepsis: reduction in the number of infectious agents
- Good handwashing technique
- Simple cleanliness (dusting, washing floors)
- Disposal of gloves
-
Sterilization (Surgical Asepsis): complete removal of all microorganisms from equipment and the environment
- Procedures used to prevent contamination before, during, and after surgery using sterile technique
- Sterile field: an area that has been designated as free of microorganisms
-
Standard Precautions: must be followed to prevent contact with potentially infectious body fluids
- Includes: blood, all body fluids, secretions and excretions except sweat, non-intact skin, mucous membranes, any unidentified body fluids
- Safety measures include:
- Handwashing
- Gloving
- Personal protective equipment (gloves, gowns, facemask, goggles, bags)
- Avoid needle recapping, if necessary use a one-handed scope technique
- Bio-spills: gloved must be worn to clean
- Apply Standard Precautions for all patients
-
Isolation Precautions (Transmission-Based Precautions): system used to reduce the risk of airborne, droplet, and contact transmission
- Used in conjunction with Standard Precautions
- Two main categories:
- Reducing transfer of disease from patient to worker
- Reducing transfer of disease from worker to patient
- Airborne Precautions: used for patients with infections that spread through the air
- Droplet Precautions: used for patients with infections that spread through droplets produced when a person coughs, sneezes, or talks
- Contact Precautions: used for patients with infections that can be spread through contact with the patient’s skin or mucous membranes
Some Infectious Diseases:
-
Hepatitis: inflammation of the liver
- HBV (Hepatitis B Virus infection): major infectious blood-borne occupational hazard for healthcare professionals
- Can be spread via several routes:
- Parenteral: blood transfusion, needle sharing by intravenous (IV) drug users, needle stick, or other sharp instrument
- Mucous membranes: blood contamination of the eye or mouth
- Sexual contact
- Perinatal: from infected mother to newborn infant
- Can be spread via several routes:
- Hepatitis A: transmitted through food and water contaminated with feces
-
Hepatitis C: primarily spread by contact with blood or blood products
- Sexual transmission is also possible, but less common
- No vaccine for HCV
-
Hepatitis D: appears only as a coinfection with hepatitis B
- Hepatitis B vaccines provide protection from HDV infection
-
Hepatitis E: transmitted through food and water contaminated with feces
- Safe and effective vaccines are available but not widely available
- Hepatitis B, C, and D are blood-borne
- Hepatitis A and E are transmitted through contaminated food and water
- HBV (Hepatitis B Virus infection): major infectious blood-borne occupational hazard for healthcare professionals
-
AIDS-HIV(Human immunodeficiency virus): virus causes AIDS (acquired immune deficiency syndrome)
- HIV-positive: individuals infected with the virus, is not having AIDS
- AIDS: when the immune system becomes weakened as a result of the virus
- Routes of transfer:
- Contaminated blood or needles
- Fluids containing blood
- Sexual transmission
- From mother to fetus via the placenta
- Through breast milk
-
TB (Tuberculosis): chronic disease caused by Mycobacterium tuberculosis bacterium
- Affects the lungs, but can infect any part of the body (spine and bone)
- Is an airborne disease, spread through the air from one person to another
- Spread through coughs, sneezes, speaking, or singing
- Communicable disease
Nosocomial Infections
- Nosocomium (Latin for hospital)
- Infection caught in a hospital is called a nosocomial infection
- Sources of nosocomial infection:
- Medical personnel: by direct skin contact - ingestion - inhalation (e.g., food handler and cooker, surgeons)
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Description
Test your knowledge on microorganisms and their role in infections. This quiz covers topics such as the characteristics of microorganisms, infection types, and the chain of infection. Understand how normal flora contributes to human health and disease.