Microorganisms and Diseases Quiz
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Questions and Answers

Which immune cells are highlighted as major players involved in immune defense against tuberculosis?

  • Dendritic cells and NK cells
  • Macrophages and CD4+ T cells (correct)
  • Macrophages and CD8+ T cells
  • Neutrophils and B cells

What is a key strategy used by M. tuberculosis to circumvent immune responses?

  • Escaping from the host cell
  • Promoting lysosome fusion
  • Preventing fusion with lysosome (correct)
  • Stimulating rapid phagocytosis

Which bacterium is highlighted as a facultative intracellular pathogen in the text?

  • M.tuberculosis (correct)
  • Mycoplasma pneumoniae
  • N.gonorrhaeae
  • N.meningitidis

What is a characteristic feature of Mycoplasma pneumoniae based on the text?

<p>Causes walking pneumonia (D)</p> Signup and view all the answers

Which bacterium causes meningitis and has sialic acid to avoid complement?

<p>N.meningitidis (C)</p> Signup and view all the answers

Which pathogen inhibits mucosal removal by releasing Tracheal Cytotoxin (TCT) from its cell wall?

<p>Chlamydia psittaci (C)</p> Signup and view all the answers

Which pathogen causes Whooping cough?

<p>Bordetella pertussis (C)</p> Signup and view all the answers

Which pathogen utilizes molecular mimicry to cause systemic lupus and erythematosus?

<p>Burkholderia spp (D)</p> Signup and view all the answers

Which pathogen demonstrates cell-to-cell spread during infection?

<p>Chlamydia psittaci (D)</p> Signup and view all the answers

Which pathogen employs adhesion, invasion, and intracellular growth to cause Gullian-Barre-Syndrome?

<p>Campylobacter jejuni (C)</p> Signup and view all the answers

What is the process that follows after Chlamydia-induced actin remodeling that facilitates entry into the host cell cytoplasm?

<p>EBs become internalized into endocytic vacuoles (C)</p> Signup and view all the answers

Which of the following organisms utilizes nutrients within the host cytoplasm, replicates, and then converts back to the infectious form when reaching a critical volume?

<p>Clostridioides difficile (C)</p> Signup and view all the answers

Which organism is a major cause of hospital-acquired infections and is currently treated with antibiotics but shows a potential risk of antibiotic resistance?

<p>Clostridioides difficile (C)</p> Signup and view all the answers

Which bacterial species is known for causing food poisoning, gas gangrene, and secreting multiple exotoxins including α-toxin, β-toxin, ε-toxin, and ι-toxin?

<p>Clostridium perfringens (C)</p> Signup and view all the answers

Which organism causes bacterial vaginosis and belongs to the Actinobacteria phylum?

<p>Gardnerella vaginalis (C)</p> Signup and view all the answers

What is the role of reticulate bodies (RB) in the Chlamydia infection process?

<p>Replicate and utilize nutrients within the host cytoplasm (A)</p> Signup and view all the answers

What triggers the conversion of reticulate bodies (RB) back to infectious extracellular forms (EB) in Chlamydia infection?

<p>Critical volume reached by the RB-filled inclusion (A)</p> Signup and view all the answers

Which phase of Chlamydia resembles a non-infectious replicative form known as the reticulate body (RB)?

<p>Utilization of nutrients within the host cytoplasm (D)</p> Signup and view all the answers

After reaching a critical volume, what process leads to the release of extracellular bodies (EB) during Chlamydia infection?

<p>Host cell lysis (B)</p> Signup and view all the answers

Which event occurs after infectious extracellular bodies (EBs) attach to adjacent host cells during Chlamydia infection?

<p>Initiation of another round of infection (B)</p> Signup and view all the answers

Which bacterium evades host-mediated killing by having sialic acid to avoid complement?

<p>Klebsiella pneumoniae (A)</p> Signup and view all the answers

Which bacterium causes a severe form of pneumonia known as Legionnaire’s disease and is found in fresh water?

<p>Legionella pneumophila (B)</p> Signup and view all the answers

Which bacterium is an obligate intracellular pathogen responsible for causing leprosy?

<p>Mycobacterium leprae (C)</p> Signup and view all the answers

Which bacteria survive inside immune cells such as macrophages?

<p>Legionella pneumophila (A)</p> Signup and view all the answers

Which bacterium has a capsule as an important virulence factor in its infection process?

<p>Legionella pneumophila (D)</p> Signup and view all the answers

Which bacterium is associated with membrane ruffling and trigger mechanism involving T3SS1 effector molecules?

<p>Shigella dysenteriae (A)</p> Signup and view all the answers

Which bacterium is known for causing opportunistic nosocomial pneumonia and sepsis?

<p>Pseudomonas aeruginosa (C)</p> Signup and view all the answers

Which bacterium is capable of forming a vacuole in macrophages by reprogramming endosomal traffic?

<p>Salmonella Typhimurium (C)</p> Signup and view all the answers

Which bacterium is unique due to its Vi antigen that inhibits phagocytosis and confers serum resistance?

<p>Salmonella Typho (B)</p> Signup and view all the answers

Which bacterium is a common cause of food poisoning and produces hydrogen sulfide (H2S)?

<p>Salmonella enterica (C)</p> Signup and view all the answers

Which bacterial toxin targets Golgi and endoplasmic reticulum to increase Cl- efflux and decrease Na+ influx in host cells?

<p>Cholera Toxin (A)</p> Signup and view all the answers

Which bacterial pathogen is best studied using ancient DNA analysis and is the causative agent of plague?

<p>Yersinia Pestis (B)</p> Signup and view all the answers

Which bacterium uses a superantigen mechanism of action and activates the immune response?

<p>Streptococcus pyogenes (B)</p> Signup and view all the answers

What is the primary habitat of Vibrio cholerae?

<p>Brackish or saltwater (B)</p> Signup and view all the answers

Which bacterium causes diseases like pharyngitis, scarlet fever, impetigo, and necrotising fasciitis?

<p>Streptococcus pyogenes (B)</p> Signup and view all the answers

Which bacterial pathogen encodes multiple virulence factors and uses molecular mimicry to target host heart myosin?

<p>Streptococcus pyogenes (C)</p> Signup and view all the answers

Which bacterial pathogen employs a high salt concentration to inhibit most bacteria except itself on Mannitol salt agar?

<p>Staphylococcus aureus (B)</p> Signup and view all the answers

What bacterial genus does not exhibit catalase activity except for Staphylococcus aureus?

<p>Streptococcus (C)</p> Signup and view all the answers

Which bacterial pathogen causes rat bite fever and Haverhill fever?

<p>Streptobacillus moniliformis (C)</p> Signup and view all the answers

Which bacterium causes a rare but severe bacterial infection associated with significant damage to deep soft tissue structures like muscle and connective tissues?

<p>Streptococcus pyogenes (C)</p> Signup and view all the answers

What symptoms can be associated with adult GI parasitism according to the text?

<p>Impaired growth (D)</p> Signup and view all the answers

Which medication combination is recommended for treating Ascaris infection?

<p>Albendazole and ivermectin (B)</p> Signup and view all the answers

How do you differentiate Necator from Ancylostoma based on the morphology mentioned in the text?

<p>Presence of cutting plates or teeth in the buccal capsule (D)</p> Signup and view all the answers

Which of the following is a characteristic of N. americanus as mentioned in the text?

<p>Has a characteristic shape of letter 'S' (C)</p> Signup and view all the answers

Which term is NOT associated with larval migration of parasitic worms according to the text?

<p>Lactose intolerance (B)</p> Signup and view all the answers

What is the potential impact of larval migration on physical fitness according to the text?

<p>Reduced physical endurance (A)</p> Signup and view all the answers

Which of the following is true regarding Old world hookworms compared to Necator hookworms?

<p>Old world hookworms have a more widespread distribution than Necator hookworms (D)</p> Signup and view all the answers

What is the route of infection for cutaneous larva migrans (CLM) caused by zoonotic infections?

<p>Percutaneous larval invasion through the skin (D)</p> Signup and view all the answers

Which of the following diseases is caused by Wuchereria bancrofti?

<p>Filariasis (B)</p> Signup and view all the answers

What is the vector responsible for transmitting Wuchereria bancrofti to humans?

<p>Mosquitoes (D)</p> Signup and view all the answers

Which filarial worm accounts for over 90% of all disease cases related to filarial infections?

<p>Wuchereria bancrofti (A)</p> Signup and view all the answers

What is the characteristic visible manifestation of diseases caused by Brugia malayi?

<p>Scrotal swelling (B)</p> Signup and view all the answers

What is the main intermediate host for Dracunculus medinensis?

<p>Copepod (B)</p> Signup and view all the answers

What is the pathology associated with Dracunculus medinensis infections?

<p>Ulcers and blisters (A)</p> Signup and view all the answers

How can Dracunculus medinensis infections be effectively treated?

<p>Worm extraction by wrapping around a stick (B)</p> Signup and view all the answers

Why is eradicating Dracunculus medinensis challenging?

<p>Behavioral and environmental factors (C)</p> Signup and view all the answers

What is the main group that N. americanus belongs to?

<p>Nematodes (D)</p> Signup and view all the answers

How do N. americanus larvae typically infect humans?

<p>Via skin penetration (D)</p> Signup and view all the answers

What is the characteristic feature used to differentiate Ancylostoma from Necator based on the text?

<p>Presence of cutting plates (B)</p> Signup and view all the answers

What are the symptoms associated with larval migration according to the text?

<p>Impaired growth, physical fitness, and cognition (D)</p> Signup and view all the answers

Which anthelminthic therapy combination is effective for curing Ascaris infection based on the text?

<p>Albendazole plus ivermectin (A)</p> Signup and view all the answers

Which term is used to describe the lung condition caused by larval migration of parasitic worms according to the text?

<p>Verminous pneumonia (B)</p> Signup and view all the answers

What is a key difference between Necator americanus and Ancylostoma duodenale?

<p>Buccal morphology (A)</p> Signup and view all the answers

Which soil-transmitted helminth (STH) infection is effectively treated with a combination of Albendazole and ivermectin?

<p>Hookworm infection (A)</p> Signup and view all the answers

How do Old world hookworms compare to Necator hookworms based on medical and veterinary importance?

<p>They have a higher prevalence and more zoonotic species. (D)</p> Signup and view all the answers

What is the significance of percutaneous larval invasion in zoonotic infections according to the text?

<p>It allows larvae to travel aimlessly within the host body. (A)</p> Signup and view all the answers

In the context of filarial infections, what role do mosquitoes play?

<p>They serve as intermediate hosts for the larval development of certain parasitic roundworms. (A)</p> Signup and view all the answers

What is the primary characteristic of Dracunculus medinensis among filarial infections discussed in the text?

<p>Formation of painful blisters and ulcers in infected individuals. (A)</p> Signup and view all the answers

What distinguishes N. americanus compared to other parasitic worms mentioned in the text?

<p>It exhibits a unique C-shaped morphology different from other hookworms. (B)</p> Signup and view all the answers

What is the most accurate statement regarding Ancylostoma spp. larval invasion based on the text?

<p>Zoonotic infections involve larval migration when people walk over sand contaminated with animal feces. (C)</p> Signup and view all the answers

How does Dracunculus medinensis primarily reproduce within the human host?

<p>By producing offspring through sexual reproduction in subcutaneous tissue (B)</p> Signup and view all the answers

What is a common symptom associated with Dracunculus medinensis infections?

<p>Localized pain at the infected area (A)</p> Signup and view all the answers

What is the most effective method for treating dracunculiasis caused by Dracunculus medinensis?

<p>Extracting the worm by wrapping it around a stick (A)</p> Signup and view all the answers

Why is Dracunculus medinensis eradication challenging?

<p>Lack of effective anti-parasitic drugs or vaccines (B)</p> Signup and view all the answers

In which host does Dracunculus medinensis mainly mature and reproduce?

<p>Final host: Human (B)</p> Signup and view all the answers

What is the characteristic feature of Dracunculus medinensis infections that leads to ulcers and blisters?

<p>Fertilized worm migrating into skin and discharging larvae (B)</p> Signup and view all the answers

What symptom is commonly associated with N. americanus adult GI parasitism according to the text?

<p>Intestinal obstruction (C)</p> Signup and view all the answers

What distinguishes Dracunculus medinensis infections from other parasitic worm infections discussed in the text?

<p>Larval migration causing verminous pneumonia (B)</p> Signup and view all the answers

Which characteristic differentiates N. americanus from Ancylostoma, based on the text?

<p>Cutting plates in the buccal capsule (B)</p> Signup and view all the answers

What treatment challenge is specifically associated with Dracunculus medinensis infections?

<p>Inaccessibility of parasites in deep tissue structures (D)</p> Signup and view all the answers

What makes N. americanus larval invasion unique compared to other hookworms discussed in the text?

<p>Larval invasion through skin penetration (C)</p> Signup and view all the answers

How does Dracunculus medinensis primarily impact physical fitness according to the text?

<p>Causes impaired physical fitness (B)</p> Signup and view all the answers

What is a notable difference between N. americanus and A. duodenale mentioned in the text?

<p>N. americanus larva can infect humans through the skin, while A. duodenale larva infect through ingestion. (B)</p> Signup and view all the answers

What makes Dracunculus medinensis particularly challenging to eradicate, as highlighted in the text?

<p>The ability of Dracunculus medinensis larvae to survive for extended periods outside of a host. (B)</p> Signup and view all the answers

Which statement best describes the impact of larval migration on physical fitness based on the text?

<p>Larval migration can result in muscle damage and impaired mobility. (A)</p> Signup and view all the answers

Why do people need to be cautious when walking barefoot over sand where cats/dogs have defecated, according to the text?

<p>To prevent cutaneous larva migrans (CLM) caused by zoonotic larval invasion. (A)</p> Signup and view all the answers

What distinguishes Necator americanus larval invasion from Ancylostoma spp., as indicated in the text?

<p>Necator americanus larvae enter the human body through ingestion, while Ancylostoma spp. larvae penetrate the skin. (B)</p> Signup and view all the answers

Which aspect of larval release during Chlamydia infection is analogous to the phenomenon seen in Dracunculus medinensis infections?

<p>Reticulate bodies (RB) convert to extracellular bodies (EB) after reaching a critical volume. (B)</p> Signup and view all the answers

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