Microfilament-Based Motility and Myosin Functions
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Questions and Answers

What protein is a calcium-sensitive switch that regulates myosin’s access to the actin microfilament?

  • Tropomyosin
  • Actin
  • Troponin (correct)
  • Myosin

What defines the distance from one Z line to another in a sarcomere?

  • Actin
  • Thick filaments
  • Myosin
  • Sarcomere length (correct)

Which type of filaments are anchored at the Z lines?

  • Thick filaments
  • Tropomyosin
  • Myosin
  • F-actin (correct)

What is responsible for muscle contraction according to the sliding-filament model?

<p>Sliding of thin filaments past thick filaments (A)</p> Signup and view all the answers

What holds the thin and thick filaments together during muscle contraction?

<p>Cross-bridges (A)</p> Signup and view all the answers

What type of structure requires energy for the sliding of thin filaments past thick filaments?

<p>Sarcomeres (C)</p> Signup and view all the answers

What is the primary function of myosins in cellular events?

<p>Muscle contraction (D)</p> Signup and view all the answers

Which statement accurately describes the structure of myosins?

<p>The globular head group binds actin and uses ATP hydrolysis for movement. (B)</p> Signup and view all the answers

In what direction are most myosins motors directed?

<p>Toward the positive end of actin filaments (A)</p> Signup and view all the answers

What is a common function of Type II myosins?

<p>Pulling arrays of actin filaments together (A)</p> Signup and view all the answers

What is the role of light chains in myosins?

<p>Regulating the ATPase for movement (B)</p> Signup and view all the answers

What is a characteristic feature of myosin II molecules?

<p>They bunch together in a staggered formation to make thick filaments. (A)</p> Signup and view all the answers

What is the role of ATP in muscle contraction?

<p>Binds to myosin (D)</p> Signup and view all the answers

In skeletal muscle cells, what leads to muscle relaxation?

<p>Decline in calcium levels due to ATP-dependent pumps (C)</p> Signup and view all the answers

What is responsible for regulating the availability of myosin-binding sites on actin filaments?

<p>Tropomyosin (C)</p> Signup and view all the answers

Which event allows myosin to bind to actin filaments during muscle contraction?

<p>Increase in calcium concentration causing tropomyosin shift (B)</p> Signup and view all the answers

Which type of muscle contraction is responsible for involuntary contractions?

<p>Smooth muscle (D)</p> Signup and view all the answers

What are the dense bodies found in smooth muscles responsible for?

<p>Anchoring actin and myosin filaments (D)</p> Signup and view all the answers

What causes a conformational change in myosin in smooth muscle cells?

<p>Myosin light-chain phosphorylation (B)</p> Signup and view all the answers

What removes phosphate from the myosin light chain in smooth muscle cells to promote relaxation?

<p><a href="dephosphorylates">MLCP</a> Myosin Light-Chain Phosphatase (D)</p> Signup and view all the answers

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