Microfilament-Based Motility and Myosin Functions
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Questions and Answers

What protein is a calcium-sensitive switch that regulates myosin’s access to the actin microfilament?

  • Tropomyosin
  • Actin
  • Troponin (correct)
  • Myosin
  • What defines the distance from one Z line to another in a sarcomere?

  • Actin
  • Thick filaments
  • Myosin
  • Sarcomere length (correct)
  • Which type of filaments are anchored at the Z lines?

  • Thick filaments
  • Tropomyosin
  • Myosin
  • F-actin (correct)
  • What is responsible for muscle contraction according to the sliding-filament model?

    <p>Sliding of thin filaments past thick filaments</p> Signup and view all the answers

    What holds the thin and thick filaments together during muscle contraction?

    <p>Cross-bridges</p> Signup and view all the answers

    What type of structure requires energy for the sliding of thin filaments past thick filaments?

    <p>Sarcomeres</p> Signup and view all the answers

    What is the primary function of myosins in cellular events?

    <p>Muscle contraction</p> Signup and view all the answers

    Which statement accurately describes the structure of myosins?

    <p>The globular head group binds actin and uses ATP hydrolysis for movement.</p> Signup and view all the answers

    In what direction are most myosins motors directed?

    <p>Toward the positive end of actin filaments</p> Signup and view all the answers

    What is a common function of Type II myosins?

    <p>Pulling arrays of actin filaments together</p> Signup and view all the answers

    What is the role of light chains in myosins?

    <p>Regulating the ATPase for movement</p> Signup and view all the answers

    What is a characteristic feature of myosin II molecules?

    <p>They bunch together in a staggered formation to make thick filaments.</p> Signup and view all the answers

    What is the role of ATP in muscle contraction?

    <p>Binds to myosin</p> Signup and view all the answers

    In skeletal muscle cells, what leads to muscle relaxation?

    <p>Decline in calcium levels due to ATP-dependent pumps</p> Signup and view all the answers

    What is responsible for regulating the availability of myosin-binding sites on actin filaments?

    <p>Tropomyosin</p> Signup and view all the answers

    Which event allows myosin to bind to actin filaments during muscle contraction?

    <p>Increase in calcium concentration causing tropomyosin shift</p> Signup and view all the answers

    Which type of muscle contraction is responsible for involuntary contractions?

    <p>Smooth muscle</p> Signup and view all the answers

    What are the dense bodies found in smooth muscles responsible for?

    <p>Anchoring actin and myosin filaments</p> Signup and view all the answers

    What causes a conformational change in myosin in smooth muscle cells?

    <p>Myosin light-chain phosphorylation</p> Signup and view all the answers

    What removes phosphate from the myosin light chain in smooth muscle cells to promote relaxation?

    <p><a href="dephosphorylates">MLCP</a> Myosin Light-Chain Phosphatase</p> Signup and view all the answers

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