Microbiology Innate & Adaptive Immunity Quiz
47 Questions
3 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What technique involved inhaling dried crusts derived from smallpox pustules?

  • Variolation (correct)
  • Vaccination
  • Attenuation
  • Inoculation

Who reasoned that introducing fluid from a cowpox pustule might protect people from smallpox?

  • The milkmaids
  • The English physician
  • Edward Jenner (correct)
  • Louis Pasteur

Which component of immunity provides the first line of defense against infection?

  • Adaptive immunity
  • Pathogen immunity
  • Vaccine immunity
  • Innate immunity (correct)

Who demonstrated the possibility of weakening a pathogen and administering the weakened strain as a vaccine?

<p>Louis Pasteur (C)</p> Signup and view all the answers

What is the primary function of the immune system?

<p>To protect animals from invading microorganisms and cancer (D)</p> Signup and view all the answers

How does the immune system respond once a foreign organism is recognized?

<p>By recruiting cells and molecules to mount an appropriate response (C)</p> Signup and view all the answers

What is remarkable about the immune recognition process?

<p>Its specificity in recognizing subtle chemical differences in foreign pathogens (B)</p> Signup and view all the answers

What distinguishes the immune system from the body’s own cells and proteins?

<p>Ability to discriminate between foreign molecules and the body’s own cells (A)</p> Signup and view all the answers

What is the consequence of the respiratory burst during phagocytosis?

<p>Increase in oxygen consumption (C)</p> Signup and view all the answers

Which receptor is responsible for binding a wide variety of polyanions on bacterial surfaces?

<p>Scavenger receptors (C)</p> Signup and view all the answers

What is the result of binding infectious agents via Toll-like receptors?

<p>Phagocytosis and release of inflammatory cytokines (C)</p> Signup and view all the answers

What happens during phagocytosis to the bacterium engulfed in a phagolysosome?

<p>It is exposed to the contents of the granules or lysosomes (C)</p> Signup and view all the answers

What is the main function of the immune system?

<p>Recognizing and eliminating foreign invaders (D)</p> Signup and view all the answers

What distinguishes the immune recognition process?

<p>Its specificity (A)</p> Signup and view all the answers

What is the response of the immune system once a foreign organism has been recognized?

<p>Recruitment of cells and molecules to mount an effectors' response (D)</p> Signup and view all the answers

What is the consequence of the respiratory burst during phagocytosis?

<p>Release of reactive oxygen species to kill engulfed microorganisms (C)</p> Signup and view all the answers

What is the process referred to as oxygen-dependent intracellular killing?

<p>Production of oxygen-containing compounds to kill bacteria (B)</p> Signup and view all the answers

Which cells can be identified by the presence of CD56 and CD16 and a lack of CD3 cell surface markers?

<p>Natural Killer (NK) cells (D)</p> Signup and view all the answers

What is the primary function of Lysozyme in oxygen-independent intracellular killing?

<p>Breakdown of bacterial cell walls (D)</p> Signup and view all the answers

Why are patients with defects in oxygen-dependent killing pathways more susceptible to serious infections?

<p>Since oxygen-dependent mechanisms are much more efficient in killing (C)</p> Signup and view all the answers

What is the process through which phagocytes cross the endothelial barrier?

<p>Diapedesis (C)</p> Signup and view all the answers

Which molecules bind to components on the surface of phagocytic cells near the site of infection?

<p>ICAM-1 and selectins (C)</p> Signup and view all the answers

What stimulates endothelial cells near the site of infection to express cell adhesion molecules?

<p>Vasodilators (D)</p> Signup and view all the answers

Which receptors on phagocytic cells bind to the 3rd component of complement, C3b?

<p>Complement receptors (A)</p> Signup and view all the answers

What is the consequence of the respiratory burst during phagocytosis?

<p>Increase in glucose and oxygen consumption (D)</p> Signup and view all the answers

Which receptors bind a wide variety of polyanions on bacterial surfaces, resulting in phagocytosis of bacteria?

<p>Scavenger receptors (D)</p> Signup and view all the answers

What happens to the bacterium during phagocytosis, after the pseudopods eventually surround and engulf it?

<p>It is enclosed in a phagolysosome (A)</p> Signup and view all the answers

Which receptors recognize broad molecular patterns called PAMPs (pathogen associated molecular patterns) on infectious agents?

<p>Toll-like receptors (B)</p> Signup and view all the answers

Which type of cells selectively kill virus-infected and malignant cells while sparing normal cells?

<p>NK cells (D)</p> Signup and view all the answers

What is the role of Fc receptors on killer cells like NK and LAK cells?

<p>Recognize, bind, and kill target cells coated with antibody (D)</p> Signup and view all the answers

What mediates antibody-dependent cellular cytotoxicity (ADCC) in killer (K) cells?

<p>Fc receptors for antibody on killer cells (A)</p> Signup and view all the answers

What happens to NK cells upon exposure to IL-2 and IFN-gamma?

<p>They become LAK cells, capable of killing malignant cells (A)</p> Signup and view all the answers

How do NK and LAK cells distinguish a normal cell from a virus-infected or malignant cell?

<p>By the expression of class I MHC molecules (B)</p> Signup and view all the answers

What is the consequence of the KIR binding to its ligand on a target cell?

<p>It inhibits killing by NK or LAK cells (D)</p> Signup and view all the answers

Why are virus-infected and malignant cells more susceptible to killing by NK and LAK cells?

<p>They downregulate expression of class I MHC molecules (D)</p> Signup and view all the answers

Which type of parasite would be unable to live or develop further in a human host?

<p>Aberrant parasite (D)</p> Signup and view all the answers

What type of host harbors the adult parasite, where the parasite replicates sexually?

<p>Definitive host (C)</p> Signup and view all the answers

Which type of host can harbor a pathogen indefinitely with no ill effects?

<p>Reservoir host (D)</p> Signup and view all the answers

What do we call the nonparasitic stages of existence of a parasite which live independently of a host?

<p>Free-living (A)</p> Signup and view all the answers

What is a compromised host?

<p>A host with impaired defense mechanisms, for example, a person with AIDS (C)</p> Signup and view all the answers

What is commensalism?

<p>An association where only the parasite benefits without detectable damage to the host (B)</p> Signup and view all the answers

What does the term 'Genus' refer to in the context of animal parasite classification?

<p>A group of closely related species (A)</p> Signup and view all the answers

What is a vector?

<p>An agent, usually an insect that transmits infection from one human host to another (A)</p> Signup and view all the answers

What are the initial symptoms of the disease caused by Naegleria fowleri?

<p>Frontal headache and fever (A)</p> Signup and view all the answers

What may happen if the olfactory lobes are involved in the disease caused by Naegleria fowleri?

<p>Disturbances in smell or taste (B)</p> Signup and view all the answers

How long does it usually take for the disease caused by Naegleria fowleri to result in death from the onset of symptoms?

<p>72 hours (A)</p> Signup and view all the answers

Which laboratory technique can be used to cultivate N. fowleri from cerebrospinal fluid (CSF) specimens?

<p>Simple wet-mount preparation (B)</p> Signup and view all the answers

More Like This

Use Quizgecko on...
Browser
Browser