Podcast
Questions and Answers
Which of the following are brand names for miconazole? (Select all that apply)
Which of the following are brand names for miconazole? (Select all that apply)
- Monistat (correct)
- Fungoid (correct)
- Moicozole (correct)
- Lotrimin AF (correct)
What is the drug class of miconazole?
What is the drug class of miconazole?
Anti fungals (topical)
What are the indications for miconazole?
What are the indications for miconazole?
Treatment of a variety of cutaneous fungal infections, including athlete's foot, jock itch, ringworm
What is the mechanism of action of miconazole?
What is the mechanism of action of miconazole?
What are the routes and dosage for miconazole?
What are the routes and dosage for miconazole?
What lab considerations are associated with miconazole?
What lab considerations are associated with miconazole?
What are the contraindications for miconazole?
What are the contraindications for miconazole?
What food or drug interactions should be noted with miconazole?
What food or drug interactions should be noted with miconazole?
What are common side effects of miconazole?
What are common side effects of miconazole?
What are the adverse effects associated with miconazole?
What are the adverse effects associated with miconazole?
What are the desired outcomes when using miconazole?
What are the desired outcomes when using miconazole?
What education should be provided to patients using miconazole?
What education should be provided to patients using miconazole?
What is the metabolism of miconazole?
What is the metabolism of miconazole?
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Study Notes
Miconazole Overview
- Brand names include Monistat, Moicozole, Fungoid, and Lotrimin AF.
Drug Classification
- Classified as topical antifungals.
Indications for Use
- Effective for treating various cutaneous fungal infections such as athlete's foot, jock itch, and ringworm.
Mechanism of Action
- Disrupts fungal cell wall synthesis, causing leakage of cellular contents.
- Inhibits biosynthesis, leading to damage of the cell wall membrane.
Administration Guidelines
- Administered topically for adults and children over 2 years old.
- Recommended application is twice daily.
- Duration of treatment:
- Jock itch: 2 weeks.
- Ringworm: 4 weeks.
Lab Considerations
- Conduct sensitivity and culture tests to guide treatment.
Contraindications
- Avoid use in individuals with hypersensitivity to miconazole or its components.
- Contraindicated in pregnancy and those with liver disease.
- Note the potential weakening of latex condoms.
Food and Drug Interactions
- Alcohol may interact adversely with miconazole.
Common Side Effects
- Possible reactions include burning, itching, local hypersensitivity, redness, stinging.
- Additional effects can include pelvic cramps, anemia, headaches, and contact dermatitis.
Adverse Effects
- May increase skin irritation at the application site.
Desired Treatment Outcomes
- Aimed at reducing skin irritation and ensuring resolution of the fungal infection.
Patient Education
- Advise to avoid contact with eyes and acknowledge potential for fabric staining.
- For athlete's foot, recommend changing socks and shoes at least once daily.
- Instruct patients to keep the area out of direct sunlight and to report any skin irritation.
Metabolism
- Miconazole is metabolized systemically.
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