Miconazole Flashcards

Questions and Answers

Which of the following are brand names for miconazole? (Select all that apply)

Monistat (correct)

Fungoid (correct)

Moicozole (correct)

Lotrimin AF (correct)

What is the drug class of miconazole?

Anti fungals (topical)

What are the indications for miconazole?

Treatment of a variety of cutaneous fungal infections, including athlete's foot, jock itch, ringworm

What is the mechanism of action of miconazole?

Affects synthesis of the fungal cell wall, allowing leakage of cellular contents and inhibiting biosynthesis, damaging cell wall membrane Signup and view all the answers

What are the routes and dosage for miconazole?

Topical (adults and children >2yrs) apply 2x daily; jock itch - 2 weeks; ringworm - 4 weeks Signup and view all the answers

What lab considerations are associated with miconazole?

Sensitivity and culture tests Signup and view all the answers

What are the contraindications for miconazole?

Hypersensitivity, additives, preservatives/bases, pregnancy, weakening of condoms, liver disease Signup and view all the answers

What food or drug interactions should be noted with miconazole?

Alcohol Signup and view all the answers

What are common side effects of miconazole?

Burning, itching, local hypersensitivity, redness, stinging, pelvic cramps, anemia, headaches, contact dermatitis Signup and view all the answers

What are the adverse effects associated with miconazole?

Increased skin irritation Signup and view all the answers

What are the desired outcomes when using miconazole?

Decreased skin irritation and resolution of infection Signup and view all the answers

What education should be provided to patients using miconazole?

Avoid eyes, may stain fabric, change socks and shoes once daily for athlete's foot, keep out of sunlight, report skin irritation Signup and view all the answers

What is the metabolism of miconazole?

Systemic Signup and view all the answers

Study Notes

Miconazole Overview

Brand names include Monistat, Moicozole, Fungoid, and Lotrimin AF.

Drug Classification

Classified as topical antifungals.

Indications for Use

Effective for treating various cutaneous fungal infections such as athlete's foot, jock itch, and ringworm.

Mechanism of Action

Disrupts fungal cell wall synthesis, causing leakage of cellular contents.
Inhibits biosynthesis, leading to damage of the cell wall membrane.

Administration Guidelines

Administered topically for adults and children over 2 years old.
Recommended application is twice daily.
Duration of treatment:
- Jock itch: 2 weeks.
- Ringworm: 4 weeks.

Lab Considerations

Conduct sensitivity and culture tests to guide treatment.

Contraindications

Avoid use in individuals with hypersensitivity to miconazole or its components.
Contraindicated in pregnancy and those with liver disease.
Note the potential weakening of latex condoms.

Food and Drug Interactions

Alcohol may interact adversely with miconazole.

Common Side Effects

Possible reactions include burning, itching, local hypersensitivity, redness, stinging.
Additional effects can include pelvic cramps, anemia, headaches, and contact dermatitis.

Adverse Effects

May increase skin irritation at the application site.

Desired Treatment Outcomes

Aimed at reducing skin irritation and ensuring resolution of the fungal infection.

Patient Education

Advise to avoid contact with eyes and acknowledge potential for fabric staining.
For athlete's foot, recommend changing socks and shoes at least once daily.
Instruct patients to keep the area out of direct sunlight and to report any skin irritation.

Metabolism

Miconazole is metabolized systemically.

Description

Test your knowledge of miconazole with these flashcards. Explore its brand names, drug class, indications, and mechanism of action. Perfect for pharmacy students and healthcare professionals looking to reinforce their understanding of this antifungal medication.