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Metaxalone Overview and Uses
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Metaxalone Overview and Uses

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@SpellboundEllipsis

Questions and Answers

What is the brand name of Metaxalone?

  • RelaxZone
  • Skelaxin (correct)
  • MuscleRelief
  • PainAway

    • What drug class does Metaxalone belong to?

    Centrally acting skeletal muscle relaxant

    What are the routes of administration for Metaxalone?

  • Intravenous
  • Subcutaneous
  • Oral tablet: 400 mg, 800 mg (correct)
  • Topical

    • What is the common FDA indication for Metaxalone?

    <p>Musculoskeletal pain or spasm</p> Signup and view all the answers

    What is the typical dosing for Metaxalone?

    <p>800 mg by mouth 3 to 4 times a day</p> Signup and view all the answers

    What is known about the mechanism of action of Metaxalone?

    <p>Has not been established. May be due to general CNS depression. Has no direct action on contractile mechanism of striated muscle.</p> Signup and view all the answers

    Renal dose adjustment is not required for Metaxalone.

    <p>False</p> Signup and view all the answers

    Which of the following are contraindications for Metaxalone?

    <p>Impaired renal function</p> Signup and view all the answers

    Are there any boxed warnings for Metaxalone?

    <p>None</p> Signup and view all the answers

    What types of agents interact with Metaxalone?

    <p>CNS depressants</p> Signup and view all the answers

    What is a common adverse reaction to Metaxalone?

    <p>Dizziness</p> Signup and view all the answers

    Rare but serious adverse reactions of Metaxalone include ________.

    <p>hemolytic anemia, leukopenia, jaundice, immune hypersensitivity reaction, maculopapular rash, slowed or difficult breathing when used in combination with opioids</p> Signup and view all the answers

    What are the efficacy monitoring parameters for Metaxalone?

    <p>Reduce in pain &amp; muscle spasms</p> Signup and view all the answers

    What are the toxicity monitoring parameters for Metaxalone?

    <p>Monitor LFTs &amp; CBC periodically</p> Signup and view all the answers

    Study Notes

    Metaxalone Overview

    • Brand name for Metaxalone is Skelaxin.
    • Classified as a centrally acting skeletal muscle relaxant.

    Administration and Dosage

    • Available in oral tablet form: 400 mg and 800 mg dosages.
    • Common dosing regimen is 800 mg by mouth 3 to 4 times daily.

    Indications and Uses

    • Primarily indicated for the treatment of musculoskeletal pain or spasms.

    Mechanism of Action

    • Mechanism has not been fully established but may involve general central nervous system depression.
    • Does not have a direct effect on striated muscle’s contractile mechanisms or nerve fibers.

    Considerations for Use

    • Renal dose adjustments are necessary; start with lower initial doses and increase carefully.
    • Contraindicated in individuals with hypersensitivity or significantly impaired renal or hepatic function.

    Safety Information

    • There are no boxed warnings associated with Metaxalone.
    • Be cautious of drug interactions with CNS depressants (e.g., opioids, benzodiazepines, alcohol) due to additive sedative effects; monitor for toxicity signs.

    Adverse Reactions

    • Common adverse reaction includes dizziness.
    • Rare but serious reactions can occur, such as hemolytic anemia, leukopenia, jaundice, immune hypersensitivity, maculopapular rash, and respiratory issues when combined with opioids.

    Monitoring Parameters

    • Efficacy monitored by reduction in pain and muscle spasms.
    • Toxicity should be monitored by periodic checks of liver function tests (LFTs) and complete blood count (CBC).

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    Description

    This quiz covers important information about Metaxalone, including its classification, administration, dosage, indications, and mechanism of action. Understand key safety considerations and the proper use of this muscle relaxant to manage musculoskeletal pain effectively.

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