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Questions and Answers
Which of the following measures the speed of P formation once ES has been made?
Which of the following measures the speed of P formation once ES has been made?
- Enzyme Inhibition
- Kcat (correct)
- Enzyme Efficiency
- Km
What does Kcat/Km measure?
What does Kcat/Km measure?
- Enzyme efficiency (correct)
- Enzyme inhibition
- Binding affinity of E and S
- Speed of P formation
What are some applications of enzyme inhibition?
What are some applications of enzyme inhibition?
- Physiological feedback mechanisms
- Enzyme kinetics
- Clinical therapies (correct)
- Enzyme efficiency
What type of inhibition is reversible and involves competitive binding of the inhibitor to the active site of the enzyme?
What type of inhibition is reversible and involves competitive binding of the inhibitor to the active site of the enzyme?
What is an example of a competitive inhibitor?
What is an example of a competitive inhibitor?
In competitive inhibition, does Vmax change?
In competitive inhibition, does Vmax change?
In uncompetitive inhibition, is Vmax lower or higher?
In uncompetitive inhibition, is Vmax lower or higher?
What happens in irreversible enzyme inhibition?
What happens in irreversible enzyme inhibition?
What happens when an activator binds to a multi-subunit allosteric enzyme?
What happens when an activator binds to a multi-subunit allosteric enzyme?
Which enzyme has a lower Vmax and lower Km compared to glucokinase?
Which enzyme has a lower Vmax and lower Km compared to glucokinase?
What turns off hexokinase?
What turns off hexokinase?
Where is glucokinase predominantly found?
Where is glucokinase predominantly found?
Why can't other tissues convert excess glucose to glycogen?
Why can't other tissues convert excess glucose to glycogen?
What is the significance of adding a phosphate group to glucose?
What is the significance of adding a phosphate group to glucose?
Which pathway is used for energy when glucose levels are low?
Which pathway is used for energy when glucose levels are low?
What does high Vmax indicate?
What does high Vmax indicate?
What is the role of aldehyde dehydrogenase?
What is the role of aldehyde dehydrogenase?
Why is hexokinase inhibited by glucose-6-P, but glucokinase is not?
Why is hexokinase inhibited by glucose-6-P, but glucokinase is not?
What does a lower Km indicate?
What does a lower Km indicate?
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