Metabolism of Drugs Quiz

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Which chemical property of alcohols increases as the carbon atom increases in the chain length?

Van der Waals interactions

Hydrogen bonding

Antibacterial potency (correct)

Water solubility

What is the property of certain chemicals that allows them to kill one type of organism while not harming others?

Selective Toxicity (correct)

Broad Spectrum Toxicity

Specific Toxicity

Non-specific Toxicity

At what temperature does pasteurization typically occur?

150°C - 200°C

100°C - 150°C

20°C - 40°C

65°C - 100°C (correct)

Which process aims to remove or kill all types of microorganisms?

Sterilization Signup and view all the answers

What happens to the antimicrobial potency of alcohols if a substituent is added?

It decreases Signup and view all the answers

What physiological effect do histamine, serotonin, epinephrine, and tyramine have?

Powerful physiological effects Signup and view all the answers

What is the purpose of oxidation reactions in drug metabolism?

To introduce a polar functional group to produce more H2O soluble compound Signup and view all the answers

Which phase of drug metabolism involves introducing a polar functional group to make the compound more soluble in water?

Phase II Signup and view all the answers

What is the primary function of reduction reactions in biotransformation?

Terminating or attenuating biological activity Signup and view all the answers

In drug metabolism, what is the role of hydrolysis reactions?

Breaking down compounds into smaller molecules by adding water Signup and view all the answers

Which surfactant is specifically mentioned as an anthelmintic surfactant?

Hexylresorcinols Signup and view all the answers

What is the main function of aromatization in drug metabolism?

To produce hydrophilic or pharmacologically inactive metabolites Signup and view all the answers

What is the primary role of Cytochrome P450 in drug metabolism?

Oxidative transformation of diverse substrates Signup and view all the answers

Which of the following reactions is NOT a major route of drug metabolism?

Carbamate formation Signup and view all the answers

What type of reaction involves the conversion of olefins/alkenes to epoxides or oxiranes during drug metabolism?

Allylic oxidation Signup and view all the answers

Which enzyme system carries out the biotransformation of xenobiotics in the body?

Mixed Function Oxidases Signup and view all the answers

Which of the following pathways leads to the formation of water-soluble glucuronide or sulfate conjugates for easy excretion in urine?

Aromatic hydroxylation Signup and view all the answers

What is the role of Aldo-Keto reductases in drug metabolism?

Reduction of aldehydes and ketones Signup and view all the answers