Metabolism of Drugs Quiz

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Questions and Answers

Which chemical property of alcohols increases as the carbon atom increases in the chain length?

  • Van der Waals interactions
  • Hydrogen bonding
  • Antibacterial potency (correct)
  • Water solubility

What is the property of certain chemicals that allows them to kill one type of organism while not harming others?

  • Selective Toxicity (correct)
  • Broad Spectrum Toxicity
  • Specific Toxicity
  • Non-specific Toxicity

At what temperature does pasteurization typically occur?

  • 150°C - 200°C
  • 100°C - 150°C
  • 20°C - 40°C
  • 65°C - 100°C (correct)

Which process aims to remove or kill all types of microorganisms?

<p>Sterilization (C)</p> Signup and view all the answers

What happens to the antimicrobial potency of alcohols if a substituent is added?

<p>It decreases (A)</p> Signup and view all the answers

What physiological effect do histamine, serotonin, epinephrine, and tyramine have?

<p>Powerful physiological effects (C)</p> Signup and view all the answers

What is the purpose of oxidation reactions in drug metabolism?

<p>To introduce a polar functional group to produce more H2O soluble compound (D)</p> Signup and view all the answers

Which phase of drug metabolism involves introducing a polar functional group to make the compound more soluble in water?

<p>Phase II (A)</p> Signup and view all the answers

What is the primary function of reduction reactions in biotransformation?

<p>Terminating or attenuating biological activity (A)</p> Signup and view all the answers

In drug metabolism, what is the role of hydrolysis reactions?

<p>Breaking down compounds into smaller molecules by adding water (B)</p> Signup and view all the answers

Which surfactant is specifically mentioned as an anthelmintic surfactant?

<p>Hexylresorcinols (C)</p> Signup and view all the answers

What is the main function of aromatization in drug metabolism?

<p>To produce hydrophilic or pharmacologically inactive metabolites (D)</p> Signup and view all the answers

What is the primary role of Cytochrome P450 in drug metabolism?

<p>Oxidative transformation of diverse substrates (C)</p> Signup and view all the answers

Which of the following reactions is NOT a major route of drug metabolism?

<p>Carbamate formation (C)</p> Signup and view all the answers

What type of reaction involves the conversion of olefins/alkenes to epoxides or oxiranes during drug metabolism?

<p>Allylic oxidation (D)</p> Signup and view all the answers

Which enzyme system carries out the biotransformation of xenobiotics in the body?

<p>Mixed Function Oxidases (A)</p> Signup and view all the answers

Which of the following pathways leads to the formation of water-soluble glucuronide or sulfate conjugates for easy excretion in urine?

<p>Aromatic hydroxylation (B)</p> Signup and view all the answers

What is the role of Aldo-Keto reductases in drug metabolism?

<p>Reduction of aldehydes and ketones (C)</p> Signup and view all the answers

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