Metabolism of Drugs Quiz
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Questions and Answers

Which chemical property of alcohols increases as the carbon atom increases in the chain length?

  • Van der Waals interactions
  • Hydrogen bonding
  • Antibacterial potency (correct)
  • Water solubility
  • What is the property of certain chemicals that allows them to kill one type of organism while not harming others?

  • Selective Toxicity (correct)
  • Broad Spectrum Toxicity
  • Specific Toxicity
  • Non-specific Toxicity
  • At what temperature does pasteurization typically occur?

  • 150°C - 200°C
  • 100°C - 150°C
  • 20°C - 40°C
  • 65°C - 100°C (correct)
  • Which process aims to remove or kill all types of microorganisms?

    <p>Sterilization</p> Signup and view all the answers

    What happens to the antimicrobial potency of alcohols if a substituent is added?

    <p>It decreases</p> Signup and view all the answers

    What physiological effect do histamine, serotonin, epinephrine, and tyramine have?

    <p>Powerful physiological effects</p> Signup and view all the answers

    What is the purpose of oxidation reactions in drug metabolism?

    <p>To introduce a polar functional group to produce more H2O soluble compound</p> Signup and view all the answers

    Which phase of drug metabolism involves introducing a polar functional group to make the compound more soluble in water?

    <p>Phase II</p> Signup and view all the answers

    What is the primary function of reduction reactions in biotransformation?

    <p>Terminating or attenuating biological activity</p> Signup and view all the answers

    In drug metabolism, what is the role of hydrolysis reactions?

    <p>Breaking down compounds into smaller molecules by adding water</p> Signup and view all the answers

    Which surfactant is specifically mentioned as an anthelmintic surfactant?

    <p>Hexylresorcinols</p> Signup and view all the answers

    What is the main function of aromatization in drug metabolism?

    <p>To produce hydrophilic or pharmacologically inactive metabolites</p> Signup and view all the answers

    What is the primary role of Cytochrome P450 in drug metabolism?

    <p>Oxidative transformation of diverse substrates</p> Signup and view all the answers

    Which of the following reactions is NOT a major route of drug metabolism?

    <p>Carbamate formation</p> Signup and view all the answers

    What type of reaction involves the conversion of olefins/alkenes to epoxides or oxiranes during drug metabolism?

    <p>Allylic oxidation</p> Signup and view all the answers

    Which enzyme system carries out the biotransformation of xenobiotics in the body?

    <p>Mixed Function Oxidases</p> Signup and view all the answers

    Which of the following pathways leads to the formation of water-soluble glucuronide or sulfate conjugates for easy excretion in urine?

    <p>Aromatic hydroxylation</p> Signup and view all the answers

    What is the role of Aldo-Keto reductases in drug metabolism?

    <p>Reduction of aldehydes and ketones</p> Signup and view all the answers

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