18 Questions
What is the role of the slowest enzyme in a metabolic pathway?
It determines the overall rate of the pathway
How can enzyme activity be modulated through gene expression?
Repression and induction
What is the effect of an allosteric effector on an enzyme?
It causes a conformational change in the enzyme
What is the mechanism of non-competitive enzyme inhibition?
The inhibitor binds to an allosteric site on the enzyme
Which type of enzyme inhibition is reversible?
Both competitive and non-competitive inhibition
What is the effect of protein phosphorylation on enzyme activity?
It can either increase or decrease enzyme activity
Which type of enzyme inhibition is irreversible?
Irreversible inhibition
What is the relationship between the substrate and a competitive inhibitor?
They bind to the same site on the enzyme
Which enzyme in a metabolic pathway is the most crucial for regulation?
The rate-limiting enzyme
Which of the following is a mechanism by which enzyme activity can be modulated?
Protein phosphorylation
What is the effect of a non-competitive inhibitor on an enzyme?
It binds to a site other than the active site, changing the enzyme's conformation.
How does the presence of an allosteric effector affect an enzyme's activity?
It changes the enzyme's conformation, either increasing or decreasing its activity.
Which of the following is a mechanism by which gene expression can modulate enzyme activity?
Repression or induction of enzyme synthesis
What is the relationship between a competitive inhibitor and the substrate of an enzyme?
The competitive inhibitor and the substrate bind to the same active site on the enzyme.
Which enzyme in a metabolic pathway is the most crucial for regulation?
The enzyme that catalyzes the first irreversible step in the pathway
What is the effect of protein phosphorylation on enzyme activity?
It can either increase or decrease the enzyme's activity, depending on the specific site of phosphorylation.
What is the effect of an irreversible enzyme inhibitor?
It binds to the enzyme and forms a stable complex, permanently inactivating the enzyme.
Which type of enzyme inhibition is reversible?
Both competitive and non-competitive inhibition
This quiz covers important concepts in metabolism, including enzymes, energy metabolism, and complex molecules such as glycogen. Topics discussed by Dr. Derick van Vuuren at Stellenbosch University.
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