Metabolic Regulation and Disorders II Quiz
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Questions and Answers

What is the key enzyme involved in glycogenesis?

  • Fructose-6-phosphate
  • Glycogen phosphorylase
  • Glycogen synthase (correct)
  • Glucose-6-phosphatase

Which mechanism regulates both glycogenesis and glycogenolysis?

  • Allosteric regulation (correct)
  • Competitive inhibition
  • Negative feedback
  • Covalent modification

Which regulatory mechanism involves the binding of a hormone to its receptor on the cell membrane?

  • Allosteric regulation
  • Feedback inhibition
  • Hormonal regulation (correct)
  • Competitive inhibition

What is the primary function of glycogen phosphorylase?

<p>Releasing glucose from glycogen (C)</p> Signup and view all the answers

Which molecule(s) lead to an increase in glycogen synthesis during the fed state?

<p>Glucose-6-phosphate, ATP, and UTP (B)</p> Signup and view all the answers

In the fasting state, what leads to an increase in glycogenolysis?

<p>Increased ADP and UDP (C)</p> Signup and view all the answers

Which form of glycogen synthase is catalyzed by cAMP-dependent protein kinase to convert it from active to inactive during the fasting state?

<p>GS-a (dephosphorylated active form) (A)</p> Signup and view all the answers

What leads to the phosphorylation of inactive GP-’b’ into active GP-‘a’ during the fasting state?

<p>Increased glucagon and norepinephrine (A)</p> Signup and view all the answers

Under uncontrolled diabetes mellitus, what is the activity level of glycogen synthase?

<p>Highly active (A)</p> Signup and view all the answers

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