Metabolic Pathways Quiz
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Questions and Answers

What is a metabolic pathway?

A metabolic pathway is a series of interconnected biochemical reactions that convert a substrate molecule or molecules, step-by-step, through a series of metabolic intermediates, eventually yielding a final product or products.

What are the two major types of metabolic pathways?

  • Oxidative and Reductive
  • Anabolic and Catabolic (correct)
  • Linear and Cyclic
  • Exergonic and Endergonic
  • Anabolic pathways require energy input.

    True (A)

    Catabolic pathways release energy.

    <p>True (A)</p> Signup and view all the answers

    What is metabolism?

    <p>Metabolism is the sum of all the chemical reactions that take place in an organism.</p> Signup and view all the answers

    What are the two types of metabolic pathways based on structure?

    <p>Linear and Cyclic (B)</p> Signup and view all the answers

    Which of the following is NOT a macromolecule?

    <p>Water (C)</p> Signup and view all the answers

    What are some examples of macromolecules?

    <p>Carbohydrates, proteins, and lipids are examples of macromolecules.</p> Signup and view all the answers

    The human body can survive by only consuming air and solar rays.

    <p>False (B)</p> Signup and view all the answers

    What is the central molecule in metabolism?

    <p>Glucose.</p> Signup and view all the answers

    What is the main function of glucose?

    <p>Glucose provides energy for the body's cells.</p> Signup and view all the answers

    Where is glucose absorbed in the body?

    <p>The small intestine.</p> Signup and view all the answers

    What type of transport mechanism is used for glucose absorption?

    <p>Facilitated diffusion.</p> Signup and view all the answers

    Glucose absorption requires energy.

    <p>False (B)</p> Signup and view all the answers

    Match the following enzymes with their functions in digestion.

    <p>Salivary amylase = Breaks down starch into smaller sugars Pepsin = Breaks down proteins into smaller peptides Pancreatic amylase = Breaks down starch into smaller sugars Lipase = Breaks down fats into fatty acids and glycerol Trypsin, chymotrypsin, carboxypeptidase = Breaks down proteins into smaller peptides</p> Signup and view all the answers

    What is the role of bile salts in lipid digestion?

    <p>Bile salts emulsify fats, breaking down large fat droplets into smaller droplets, increasing the surface area for lipase to act on.</p> Signup and view all the answers

    What is the function of chylomicrons?

    <p>Chylomicrons transport lipids from the small intestine to the liver and other tissues.</p> Signup and view all the answers

    The body can store unlimited amounts of amino acids.

    <p>False (B)</p> Signup and view all the answers

    What is the name of the molecule that is called the "energy currency" of the cell?

    <p>Adenosine triphosphate (ATP).</p> Signup and view all the answers

    ATP is a large and complex molecule.

    <p>False (B)</p> Signup and view all the answers

    Where is the energy stored in ATP?

    <p>In the bonds between the phosphate groups.</p> Signup and view all the answers

    What process is used to transfer energy from ATP to other molecules?

    <p>Phosphorylation.</p> Signup and view all the answers

    What is the name of the process that couples the hydrolysis of ATP with an endergonic reaction?

    <p>Energy coupling.</p> Signup and view all the answers

    What is the first step in glucose breakdown?

    <p>Glycolysis.</p> Signup and view all the answers

    Glycolysis requires oxygen.

    <p>False (B)</p> Signup and view all the answers

    What is the name of the enzyme that catalyzes the first step of glycolysis?

    <p>Hexokinase.</p> Signup and view all the answers

    The second step of glycolysis is also an irreversible reaction.

    <p>True (A)</p> Signup and view all the answers

    All carbohydrates enter glycolysis at the same point?

    <p>False (B)</p> Signup and view all the answers

    What are the two products of glycolysis?

    <p>Pyruvate and ATP.</p> Signup and view all the answers

    Pyruvate is the end product of glycolysis.

    <p>False (B)</p> Signup and view all the answers

    What is the Cori cycle?

    <p>The Cori cycle is a metabolic pathway that transports lactate from the muscles to the liver, where it is converted back to glucose.</p> Signup and view all the answers

    The Cori cycle involves both anabolic and catabolic reactions.

    <p>True (A)</p> Signup and view all the answers

    What is the function of electron carriers in metabolism?

    <p>Electron carriers transport electrons between molecules in metabolic pathways, facilitating redox reactions.</p> Signup and view all the answers

    What is the name of a crucial electron carrier in metabolism?

    <p>NADH.</p> Signup and view all the answers

    NADH is the oxidized form of NAD.

    <p>False (B)</p> Signup and view all the answers

    Lactate dehydrogenase catalyzes the conversion of pyruvate to lactate.

    <p>True (A)</p> Signup and view all the answers

    Why is lactate production important during exercise?

    <p>Lactate production allows skeletal muscles to continue producing ATP during intense exercise, even in the absence of sufficient oxygen.</p> Signup and view all the answers

    Lactate is a toxic waste product that is harmful to the body.

    <p>False (B)</p> Signup and view all the answers

    What is the astrocyte-neuron lactate shuttle?

    <p>The astrocyte-neuron lactate shuttle is a metabolic pathway in the brain where astrocytes produce lactate from glucose and release it to neurons, which use it as an energy source.</p> Signup and view all the answers

    The classical view of neuroenergetics emphasizes the role of astrocytes in providing energy to neurons.

    <p>False (B)</p> Signup and view all the answers

    What is the new paradigm shift in neuroenergetics?

    <p>The new paradigm shift in neuroenergetics recognizes the active role of astrocytes in providing energy to neurons.</p> Signup and view all the answers

    Galactosemia is caused by a defect in the breakdown of galactose.

    <p>True (A)</p> Signup and view all the answers

    Fructose intolerance is caused by a deficiency in aldolase.

    <p>True (A)</p> Signup and view all the answers

    Flashcards

    Metabolic Pathway

    A series of biochemical reactions converting substrates step-by-step to final products.

    Anabolic Pathway

    A metabolic pathway that synthesizes larger molecules from smaller ones, requiring energy.

    Catabolic Pathway

    A metabolic pathway that breaks down larger molecules into smaller ones, releasing energy.

    Glycolysis

    The first step in glucose breakdown to extract energy; an anaerobic process.

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    ATP (Adenosine Triphosphate)

    The main energy carrier in cells; releases energy when phosphate bonds are broken.

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    Phosphorylation

    The process of adding a phosphate group to a molecule, often activating it.

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    Electron Carriers

    Compounds that transport high-energy electrons in metabolic pathways.

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    NAD/NADH

    Nicotinamide adenine dinucleotide; an electron carrier that can be oxidized (NAD+) or reduced (NADH).

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    Lipase

    An enzyme secreted by the pancreas that digests lipids into fatty acids and monoglycerides.

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    Chylomicrons

    Lipoprotein complexes that transport absorbed lipids from the intestinal cells to the lymphatic system.

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    Proteins and Digestion

    Proteins are broken down into amino acids by enzymes like pepsin and trypsin in the digestive system.

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    Amino Acid Transport

    Amino acids are absorbed through the intestinal epithelium using various transport mechanisms.

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    Endergonic Reaction

    A reaction that requires energy input; products have more energy than reactants.

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    Exergonic Reaction

    A reaction that releases energy; products have less energy than reactants.

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    Homeostatic Neuroenergetics

    The concept of how the brain regulates energy supply, primarily through glucose metabolism.

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    Cori Cycle

    The cycle that transports lactate from anaerobic cells to the liver for glucose production.

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    Emulsification

    The process by which large lipid droplets are broken into smaller droplets for digestion.

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    Sodium-Potassium Pump

    A cellular mechanism that establishes ion gradients, crucial for glucose transport.

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    Facilitated Diffusion

    The process of moving substances across a cell membrane with the help of transport proteins.

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    Krebs Cycle

    A series of enzyme-catalyzed chemical reactions for energy production via oxidation of acetyl-CoA.

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    Oxidative Phosphorylation

    The final stage of cellular respiration; ATP is produced using the energy from electrons.

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    Gut Microbiota

    The community of microorganisms in the digestive system; helps break down undigested food.

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    Bile Salts

    Compounds produced by the liver that aid in lipid digestion and emulsification.

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    Tripeptides

    Chains of three amino acids linked together, formed during protein digestion.

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    Lactate

    A by-product of anaerobic metabolism; can be used by the liver to produce glucose.

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    Study Notes

    Metabolic Pathways

    • Metabolic pathways are a series of interconnected biochemical reactions.
    • These reactions convert a substrate molecule, step-by-step, into a final product.
    • Metabolic pathways can be linear or cyclic.

    Two Major Types of Metabolic Pathways

    • Catabolism: This pathway breaks down complex molecules into simpler ones, releasing energy.
    • Anabolism: This pathway builds complex molecules from simpler ones, requiring energy.

    Metabolism

    • Metabolism encompasses all chemical reactions occurring within an organism.
    • Catabolism breaks down large molecules into smaller ones, releasing energy.
    • Anabolism synthesizes complex molecules from simpler ones, consuming energy.

    Cell Metabolism

    • Food (macromolecules) are broken down into simpler molecules (micromolecules) during catabolism, releasing energy.
    • Energy from catabolism powers anabolism, building biomolecules.
    • Heat is released as a byproduct of both processes.

    Digestion Pathways

    • Digestion breaks down complex carbohydrates, lipids, and proteins into simpler subunits.
    • Different enzymes are used for each category (carbohydrates: amylase; lips: lipase; proteins: pepsin, trypsin, chymotrypsin, carboxypeptidase).
    • The process occurs in different parts of the digestive tract.
    • The final products of digestion are absorbed into the bloodstream.

    Glucose Utilization

    • Glucose is crucial for cellular energy.
    • It is converted to glycogen, a storage form, in various tissues.
    • Glucose is oxidized via glycolysis, yielding pyruvate.
    • Glucose follows several pathways for various functions (synthesis of structural polymers, pentose phosphate pathway).

    ATP (Adenosine Triphosphate)

    • ATP is the energy currency of the cell.
    • ATP hydrolysis (breaking down ATP) releases energy for work performed inside the cell.
    • Cells couple the exergonic reaction of ATP hydrolysis to the endergonic anabolic reactions.
    • ATP energy transfer is facilitated through phosphorylation.

    Electron Carriers

    • Electron carriers facilitate electron transfer in biological systems.
    • NAD+ and FAD are examples of important electron carriers derived from B vitamins.
    • They temporarily store high-energy electrons and protons (H+).
    • NADH carries high-energy electrons.

    Glycolysis

    • Glycolysis is the initial step in glucose breakdown.
    • It is an anaerobic process, meaning it does not require oxygen.
    • Glycolysis converts glucose into pyruvate, producing ATP and NADH.

    Fate of Pyruvate and NADH

    • In anaerobic conditions, pyruvate is converted to lactate or ethanol.
    • In aerobic conditions, pyruvate is further oxidized to acetyl-CoA for the citric acid cycle.
    • NADH is oxidized to NAD+, transferring energy.

    Regulation of Glycolysis

    • The rate of glycolysis is controlled by the availability of substrates and the activity of enzymes like hexokinase, phosphofructokinase, and pyruvate kinase.
    • Concentrations of fructose-6-phosphate, ATP, and citrate influence enzyme activity

    Other Sugars and Glycolysis

    • Various sugars, including fructose, lactose, and sucrose, can be converted to glucose-6-phosphate and enter the glycolytic pathway.

    Glycolysis Disorders

    • Disorders arising from enzyme deficiencies in the glycolytic pathway can lead to problems.
    • Examples of specific disorders include galactosemia and fructose intolerance.

    Cori Cycle

    • Cori cycle is a metabolic pathway where lactate, produced by anaerobic metabolism in tissues, is transported to the liver, where it is converted back into glucose.

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    Description

    Test your knowledge on metabolic pathways, including catabolism and anabolism. Understand how these processes interconnect to support cellular function and energy dynamics. Explore the roles of various biochemical reactions in metabolism.

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