Podcast
Questions and Answers
Which process converts pyruvate to acetyl-CoA under aerobic conditions?
Which process converts pyruvate to acetyl-CoA under aerobic conditions?
- Oxidative process (correct)
- Reductive process
- Decarboxylation
- Fermentation
What is the main function of pyruvate dehydrogenase in metabolism?
What is the main function of pyruvate dehydrogenase in metabolism?
- Generates NADH from pyruvate
- Catalyzes the conversion of acetyl-CoA to pyruvate
- Facilitates gluconeogenesis
- Committed step between carbohydrate metabolism and lipid metabolism (correct)
Which enzyme is part of the pyruvate dehydrogenase complex and converts pyruvate to acetyl-CoA?
Which enzyme is part of the pyruvate dehydrogenase complex and converts pyruvate to acetyl-CoA?
- Phosphofructokinase
- Pyruvate kinase
- Dihydrolipoyl transacetylase (correct)
- Pyruvate carboxylase
Which of the following is a molecule NOT made from pyruvate as mentioned in the text?
Which of the following is a molecule NOT made from pyruvate as mentioned in the text?
In anaerobic conditions, what are the possible products of pyruvate metabolism?
In anaerobic conditions, what are the possible products of pyruvate metabolism?
What effect does phosphorylation have on the E1 subunit of pyruvate dehydrogenase?
What effect does phosphorylation have on the E1 subunit of pyruvate dehydrogenase?
Which molecule regulates the activity of pyruvate dehydrogenase phosphatase?
Which molecule regulates the activity of pyruvate dehydrogenase phosphatase?
What is the impact of NADH on pyruvate dehydrogenase function?
What is the impact of NADH on pyruvate dehydrogenase function?
Which of the following molecules activates the E1 subunit of pyruvate dehydrogenase?
Which of the following molecules activates the E1 subunit of pyruvate dehydrogenase?
How does acetyl-CoA influence pyruvate dehydrogenase?
How does acetyl-CoA influence pyruvate dehydrogenase?
What is the primary function of pyruvate carboxylase in gluconeogenesis?
What is the primary function of pyruvate carboxylase in gluconeogenesis?
Which enzyme is responsible for converting pyruvate to lactate anaerobically?
Which enzyme is responsible for converting pyruvate to lactate anaerobically?
What drives the conversion of 2-PG to PEP in glycolysis?
What drives the conversion of 2-PG to PEP in glycolysis?
Which process involves the formation of acetaldehyde from pyruvate?
Which process involves the formation of acetaldehyde from pyruvate?
Which step in glycolysis is considered committed and irreversible?
Which step in glycolysis is considered committed and irreversible?
What is the role of pyruvate decarboxylase in the context of pyruvate metabolism?
What is the role of pyruvate decarboxylase in the context of pyruvate metabolism?
What is the role of Mg2+ or Mn2+ in the third irreversible reaction of glycolysis?
What is the role of Mg2+ or Mn2+ in the third irreversible reaction of glycolysis?
Which enzyme is involved in the transamination of oxaloacetate into aspartate in pyruvate metabolism?
Which enzyme is involved in the transamination of oxaloacetate into aspartate in pyruvate metabolism?
Which molecule is generated at the end of the energy-yielding stage in glycolysis?
Which molecule is generated at the end of the energy-yielding stage in glycolysis?
What is the effect of product removal on the dehydration of 2-PG to PEP in glycolysis?
What is the effect of product removal on the dehydration of 2-PG to PEP in glycolysis?
What is the primary product of the catabolism of monosaccharides?
What is the primary product of the catabolism of monosaccharides?
Which enzyme catalyzes the conversion of pyruvate to acetyl-CoA?
Which enzyme catalyzes the conversion of pyruvate to acetyl-CoA?
Which process involves the synthesis of new glucose using pyruvate?
Which process involves the synthesis of new glucose using pyruvate?
In glycolysis, which molecule serves as the primary substrate for the subsequent step?
In glycolysis, which molecule serves as the primary substrate for the subsequent step?
What is the key role of pyruvate dehydrogenase in cellular metabolism?
What is the key role of pyruvate dehydrogenase in cellular metabolism?
Which molecule plays a critical cofactor role in many enzymatic reactions, where electrons transferred to it are used in subsequent reactions such as the electron transport chain?
Which molecule plays a critical cofactor role in many enzymatic reactions, where electrons transferred to it are used in subsequent reactions such as the electron transport chain?
In which step of glycolysis does the FIRST ATP molecule get generated through substrate-level phosphorylation?
In which step of glycolysis does the FIRST ATP molecule get generated through substrate-level phosphorylation?
Which enzyme catalyzes the isomerization of 2-phosphoglycerate to 3-phosphoglycerate in glycolysis?
Which enzyme catalyzes the isomerization of 2-phosphoglycerate to 3-phosphoglycerate in glycolysis?
Which molecule acts as an important regulator of hemoglobin and is formed as an intermediate in the reaction catalyzed by mutase?
Which molecule acts as an important regulator of hemoglobin and is formed as an intermediate in the reaction catalyzed by mutase?
What drives the conversion of 3-phosphoglycerate to 2-phosphoglycerate, according to the text?
What drives the conversion of 3-phosphoglycerate to 2-phosphoglycerate, according to the text?
Which enzyme is responsible for the conversion of oxaloacetate to phosphoenolpyruvate in gluconeogenesis?
Which enzyme is responsible for the conversion of oxaloacetate to phosphoenolpyruvate in gluconeogenesis?
Which enzyme is involved in the conversion of fructose-1,6-bisphosphate to fructose-6-phosphate in gluconeogenesis?
Which enzyme is involved in the conversion of fructose-1,6-bisphosphate to fructose-6-phosphate in gluconeogenesis?
Which enzyme is responsible for the conversion of glucose-6-phosphate to glucose in gluconeogenesis?
Which enzyme is responsible for the conversion of glucose-6-phosphate to glucose in gluconeogenesis?
Which of the following is a glucogenic precursor for gluconeogenesis?
Which of the following is a glucogenic precursor for gluconeogenesis?
Which enzyme catalyzes the conversion of pyruvate to oxaloacetate in gluconeogenesis?
Which enzyme catalyzes the conversion of pyruvate to oxaloacetate in gluconeogenesis?
Which enzyme consumes one ATP equivalent during the conversion of pyruvate to oxaloacetate?
Which enzyme consumes one ATP equivalent during the conversion of pyruvate to oxaloacetate?
The conversion of fructose-1,6-bisphosphate to fructose-6-phosphate is catalyzed by which enzyme in gluconeogenesis?
The conversion of fructose-1,6-bisphosphate to fructose-6-phosphate is catalyzed by which enzyme in gluconeogenesis?
