Podcast
Questions and Answers
Which of the following is true about membrane transporters in pharmacokinetics?
Which of the following is true about membrane transporters in pharmacokinetics?
Which transporter is overexpressed in tumor cells after exposure to cytotoxic anticancer agents?
Which transporter is overexpressed in tumor cells after exposure to cytotoxic anticancer agents?
What is the consequence of decreased expression of influx transporters required for certain drugs to access the tumor?
What is the consequence of decreased expression of influx transporters required for certain drugs to access the tumor?
Which category of adverse drug responses is associated with decreased uptake or excretion at clearance organs?
Which category of adverse drug responses is associated with decreased uptake or excretion at clearance organs?
Signup and view all the answers
Which transporter is associated with resistance to antiviral nucleoside analogues when overexpressed?
Which transporter is associated with resistance to antiviral nucleoside analogues when overexpressed?
Signup and view all the answers
Which of the following is NOT a function of membrane transporters in pharmacokinetics?
Which of the following is NOT a function of membrane transporters in pharmacokinetics?
Signup and view all the answers
Which of the following drug classes is NOT associated with decreased uptake mediated by reduced expression of influx transporters?
Which of the following drug classes is NOT associated with decreased uptake mediated by reduced expression of influx transporters?
Signup and view all the answers
Which transporter is associated with resistance to antiviral nucleoside analogues when overexpressed?
Which transporter is associated with resistance to antiviral nucleoside analogues when overexpressed?
Signup and view all the answers
Which category of adverse drug responses is associated with increased efflux of hydrophobic drugs?
Which category of adverse drug responses is associated with increased efflux of hydrophobic drugs?
Signup and view all the answers
What is the consequence of reduced expression of influx transporters required for certain drugs to access the tumor?
What is the consequence of reduced expression of influx transporters required for certain drugs to access the tumor?
Signup and view all the answers
