Membrane Transport and Permeability Quiz

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Questions and Answers

What is the main factor that determines the rate of diffusion of a molecule across a membrane?

  • Presence of hydrophobic regions in the molecule
  • Temperature of the surrounding environment
  • Charge of the molecule
  • Size of the molecule and its association with water (correct)

What is the resting membrane potential primarily a result of?

  • Presence of negatively charged ions only
  • Active transport and passive diffusion (correct)
  • Concentration gradient of ions
  • Electrochemical gradient only

Which ion tends to diffuse out of the cell through potassium channels to reach equilibrium?

  • K+ (correct)
  • Na+
  • Cl-
  • Ca2+

What is the electrochemical gradient of a charged solute a combination of?

<p>Concentration gradient and charge of the solute (A)</p> Signup and view all the answers

How do proteins associate with the plasma membrane based on their topology?

<p>Bound by a covalently attached lipid chain (B)</p> Signup and view all the answers

Which ions result in a difference in electrical charge across the membrane to establish the resting membrane potential?

<p>[K⁺] and [Na⁺] (C)</p> Signup and view all the answers

Which factor contributes to making the interior of the cell more negative during resting membrane potential?

<p>[K⁺] diffusing out through potassium channels (C)</p> Signup and view all the answers

What type of molecules can easily pass through the lipid bilayer of the cell membrane?

<p>Nonpolar molecules (B)</p> Signup and view all the answers

What is the main function of transport proteins in the cell membrane?

<p>Facilitate the movement of specific molecules across the membrane (C)</p> Signup and view all the answers

What percentage of all membrane proteins are transport proteins?

<p>30% (D)</p> Signup and view all the answers

Why do cells need to transfer molecules and ions across their membranes?

<p>To maintain homeostasis (D)</p> Signup and view all the answers

Which part of the cell contains a liquid matrix surrounding organelles?

<p>Cytosol (ICF) (D)</p> Signup and view all the answers

What allows cells to maintain different solute concentrations in their cytosol compared to the extracellular fluid?

<p>Selective permeability of the plasma membrane (B)</p> Signup and view all the answers

What allows transport proteins in the cell membrane to be specific to certain molecules?

<p>'Lock-and-key' interactions with molecules (A)</p> Signup and view all the answers

What is the role of Na+/Ca2+ exchange inhibitors?

<p>Removing Ca2+ from plasma membranes (B)</p> Signup and view all the answers

Where is the NCKX2 Na+/Ca2+-K+ exchanger located?

<p>Neuronal cell membranes (D)</p> Signup and view all the answers

What cellular mechanisms does the Na+/Ca2+ exchanger (NCX) participate in?

<p>Exchanging Na+ for Ca2+ across the plasma membrane (D)</p> Signup and view all the answers

What is the main function of the Na+, K+-ATPase in animal cells?

<p>Balancing Na+ and K+ concentrations across the plasma membrane (B)</p> Signup and view all the answers

What are the key roles of NCKX2 Na+/Ca2+-K+ exchanger?

<p>Influencing synaptic plasticity (A)</p> Signup and view all the answers

Which organelle is NOT mentioned as a location where Ca2+ can be found in excitable cells?

<p>Golgi apparatus (C)</p> Signup and view all the answers

How does the NCKX2 Na+/Ca2+-K+ exchanger contribute to cognitive functions?

<p>By enhancing Ca2+ clearance in neuronal cells (D)</p> Signup and view all the answers

What types of sensations can the skin sense?

<p>Vibration, pressure, stretch, and touch (B)</p> Signup and view all the answers

How do leak channels differ from gated channels in terms of functionality?

<p>Gated channels require external stimuli to open (A)</p> Signup and view all the answers

What is the significance of the selectivity filter in K⁺ channels?

<p>It dehydrates ions to facilitate their passage (B)</p> Signup and view all the answers

Where are aquaporins abundant and what is their function there?

<p>Facilitate osmotic water flow in cells that secrete or reabsorb water (D)</p> Signup and view all the answers

How many isoforms of aquaporins have been identified in mammalian cells?

<p>10 (D)</p> Signup and view all the answers

What is the role of Anti-diuretic hormone (ADH) in relation to aquaporins?

<p>It increases the expression of aquaporins for water reabsorption (D)</p> Signup and view all the answers

How does Na⁺ size affect its passage through K⁺ channels?

<p>Na⁺ cannot be accommodated by the filter due to being smaller than K⁺ (B)</p> Signup and view all the answers

What happens to ions as they pass through the selectivity filter of K⁺ channels?

<p>They dehydrate and interact with carbonyl groups (B)</p> Signup and view all the answers

In which type of cells are aquaporins predominantly present?

<p>Cells that secrete or reabsorb high amounts of water (B)</p> Signup and view all the answers

Which type of membrane transport protein forms pores for specific solute transfer?

<p>Channels (D)</p> Signup and view all the answers

In which state of a transporter are the binding sites for solutes exposed to the inside of the cell?

<p>Inward-open state (B)</p> Signup and view all the answers

Which type of membrane transporter undergoes a series of conformational changes to transfer solutes across the membrane?

<p>Carriers (C)</p> Signup and view all the answers

What type of transport is always passive?

<p>Transport through channels (C)</p> Signup and view all the answers

Which type of membrane protein interacts more weakly with solutes compared to transporters?

<p>Channels (B)</p> Signup and view all the answers

Mechanosensitive channels convert ____________ stimuli to chemical or electrical signals.

<p>Mechanical (C)</p> Signup and view all the answers

Which type of transporter can transfer solutes passively or actively?

<p>Carriers (A)</p> Signup and view all the answers

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