Megaloblastic Anemia: B12 and Folate Deficiencies
20 Questions
1 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

Which vitamin is involved in the conversion of Homocysteine to Methionine?

  • Vitamin D
  • Vitamin C
  • Vitamin B12 (correct)
  • Vitamin K

Which form of vitamin B12 is the main form in human plasma?

  • Methylcobalamin (correct)
  • Cyanocobalamin
  • Hydroxocobalamin
  • Deoxyadenosylcobalamin

What are the main forms of vitamin B12 in tissues?

  • Deoxyadenosylcobalamin (correct)
  • Cyanocobalamin
  • Hydroxocobalamin
  • Methylcobalamin

Which nutrient is essential for maintaining the active form of folate inside the cells?

<p>Vitamin B12 (D)</p> Signup and view all the answers

What is the main cause of megaloblastic anemia according to the given information?

<p>Vitamin B12 deficiency (C)</p> Signup and view all the answers

What is the most common cause of folate deficiency?

<p>Reduced intake in strict vegetarians (C)</p> Signup and view all the answers

Which condition is characterized by a combination of megaloblastic anemia, glossitis, and neuropathy?

<p>Pernicious anemia (A)</p> Signup and view all the answers

Which form of folic acid is the most important in body fluids?

<p>Methyltetrahydrofolate monoglutamate (A)</p> Signup and view all the answers

What is the main cause of cobalamin deficiency in the elderly?

<p>Gastrectomy (C)</p> Signup and view all the answers

Which blood cell abnormality is commonly seen in megaloblastic anemia?

<p>Normochromic, macrocytosis (C)</p> Signup and view all the answers

Which clinical feature is NOT associated with cobalamin deficiency?

<p>Sterility (A)</p> Signup and view all the answers

What is the most common cause of folate deficiency?

<p>Reduced intake (D)</p> Signup and view all the answers

What is the main form of vitamin B12 in human plasma?

<p>Cyanocobalamin (D)</p> Signup and view all the answers

Which condition is characterized by a combination of megaloblastic anemia, glossitis, and neuropathy?

<p>Pernicious anemia (B)</p> Signup and view all the answers

What is the best known megaloblastic anemia due to cobalamin deficiency?

<p>Pernicious anemia (B)</p> Signup and view all the answers

What is the main function of vitamin B12 in the conversion of Homocysteine to Methionine?

<p>Maintaining the active form of folate inside the cells (D)</p> Signup and view all the answers

Which form of vitamin B12 is primarily utilized in the treatment of B12 deficiency?

<p>Hydroxocobalamin (D)</p> Signup and view all the answers

What happens to Homocysteine when Vitamin B12 is not available to maintain the active form of folate?

<p>It accumulates and leads to cardiovascular diseases (D)</p> Signup and view all the answers

What is the main function of folate inside the cells that is important for DNA synthesis?

<p>Serving as a precursor for nucleotide synthesis (D)</p> Signup and view all the answers

Why is megaloblastic anemia characterized by distinctive abnormalities in blood and marrow?

<p>Impaired DNA synthesis affects the maturation of blood cells (A)</p> Signup and view all the answers

More Like This

Megaloblastic Anemia Overview
12 questions

Megaloblastic Anemia Overview

StimulatingResilience avatar
StimulatingResilience
Megaloblastic Anemia and Vitamin Deficiencies
20 questions
Megaloblastic Anemia
24 questions

Megaloblastic Anemia

UnboundMaracas avatar
UnboundMaracas
Use Quizgecko on...
Browser
Browser